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ultrasound diagnosis of fatal anomalies

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MULTIPLE PREGNANCY

Fig. 15.11 Twin reversed arterial perfusion (TRAP

sequence). This demonstrates the site of communication

of the two fetal circulations on the

placental surface.

Fig. 15.12 Twin reversed arterial perfusion (TRAP

sequence). The placenta and fetus after abortion at

22 weeks of gestation.

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2

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4

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at short intervals is recommended. It is important

to exclude fetal hydrops and cardiac failure

in the “pump twin.” The following therapeutic

options are available: 1, administration of digitalis

to the mother; 2, amniotic fluid aspiration

to reduce polyhydramnios; 3, fetoscopic ligation

of the umbilical cord of the recipient twin. Administration

of indomethacin may also help in case

of hydramnios.

Procedure after birth: Intensive treatment of the

newborn is required, depending on the gestational

age and presence of cardiac insufficiency

or hydrops.

References

Borrell A, Pesarrodona A, Puerto B, Deulofeu P, Fuster JJ,

Fortuny A. Ultrasound diagnostic features of twin

reversed arterial perfusion sequence. Prenat Diagn

1990; 10: 443–8.

Gembruch U, Viski S, Bagamery K, Berg C, Germer U.

Twin reversed arterial perfusion sequence in twinto-twin

transfusion syndrome after the death of the

donor co-twin in the second trimester. Ultrasound

Obstet Gynecol 2001; 17: 153–6.

Mohanty C, Mishra OP, Singh CP, Das BK, Singla PN.

Acardiac anomaly spectrum. Teratology 2000; 62:

356–9.

Osborn P, Gross TL, Shah JJ, Ma L. Prenatal diagnosis of

fetal heart failure in twin reversed arterial perfusion

syndrome. Prenat Diagn 2000; 20: 615–7.

Sanjaghsaz H, Bayram MO, Qureshi F. Twin reversed

arterial perfusion sequence in conjoined, acardiac,

acephalic twins associated with a normal triplet: a

case report. J Reprod Med 1998; 43: 1046–50.

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