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Nutrition Interventions for Children with Special Health Care Needs

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Chapter 22 - Ketogenic Diet <strong>for</strong> Seizure Disorders<br />

Assessment Intervention Evaluation/Outcome<br />

Albumin, Prealbumin If albumin is low, increase protein intake. Albumin levels <strong>with</strong>in normal limits.<br />

• MD to determine if decrease in<br />

anticonvulsants is indicated<br />

AED (antiepileptic medication) levels Some anticonvulsants can have an increase in medication level when<br />

a state of ketosis is present.<br />

Normal AST and ALT levels<br />

Fat absorption/metabolism may be decreased in liver disease - KD<br />

can alter liver function due to high load of fat<br />

Aspartate aminotransferase (AST)<br />

• High AST and ALT may indicate the need to<br />

• decrease ratio<br />

Alanine aminotransferase (ALT)<br />

• Maintain normal hematocrit and<br />

hemoglobin.<br />

• Maintain adequate hydration,<br />

based on fluid needs in mLs per<br />

kilogram<br />

Complete blood count Close physician supervision is necessary to evaluate.<br />

• Provide iron supplement if anemic.<br />

• Elevated hemoglobin and hematocrit may indicate fluid<br />

deficit; obtain fluid intake history, tease out possible causes,<br />

recommend/re-teach family as appropriate<br />

• AM Ketones: consistent level,<br />

individualized <strong>for</strong> each child<br />

• PM Ketones: consistent level,<br />

individualized <strong>for</strong> each child<br />

• Discontinue once child has<br />

stabilized on the diet<br />

• Can be useful to check <strong>for</strong><br />

hyperketosis, and to check the<br />

effects of foods eaten that are<br />

not allowed on the diet (lower<br />

ketosis than usual).<br />

Ideally, urine ketones should be checked every morning and<br />

afternoon. If ketones are checked just once per day, then afternoon<br />

or evening is necessary. <strong>Care</strong>givers should log ketone levels daily<br />

along <strong>with</strong> seizure activity to help evaluate the success of the diet.<br />

Urine ketone levels<br />

• Checked at same time twice<br />

daily, useful at the beginning of<br />

the diet.<br />

• After initial start, only a good<br />

indicator of dehydration or<br />

hyperketosis in the context of<br />

decreased oral intake of fluids or<br />

food.<br />

252 <strong>Nutrition</strong> <strong>Interventions</strong> <strong>for</strong> <strong>Children</strong> With <strong>Special</strong> <strong>Health</strong> <strong>Care</strong> <strong>Needs</strong><br />

Consistent range depending on<br />

child’s response to the KD.<br />

Betahydroxybutyric Acid<br />

Large ketone body found in serum,<br />

considered the most reliable method<br />

<strong>for</strong> determining level of ketosis

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