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Nutrition Interventions for Children with Special Health Care Needs

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Chapter 5 - Medication-Nutrient Interactions<br />

Table 5-1: Medication—Nutrient Interactions<br />

Assessment Intervention Evaluation/Outcome<br />

See the intervention below <strong>for</strong> each type of medication<br />

In addition to the <strong>Nutrition</strong> Assessment<br />

described in Chapter 1, complete the<br />

assessment indicated below<br />

ANTICONVULSANTS Examples: Any of the following alone or in combination <strong>with</strong> other anticonvulsants: phenobarbital; phenytoin (Dilantin);<br />

carbamazepine (Tegretol); primidone (Mysoline); valproic acid (Depakene/Depakate)<br />

Dietary intake of all nutrients<br />

is adequate<br />

If intake of any nutrient is less than the DRI/RDA:<br />

• Counsel caregiver/patient about food sources of nutrients<br />

• Recommend multivitamin/mineral supplement at DRI/RDA levels<br />

• Monitor <strong>for</strong> weight changes<br />

Assess diet <strong>for</strong> overall nutrient intake.<br />

Check specifically vitamin D, folic acid,<br />

other B vitamins, vitamin C, Vitamin K,<br />

and calcium<br />

Monitor <strong>for</strong> weight gain, weight loss,<br />

diarrhea, and constipation<br />

Assess indicators of bone mineralization:<br />

Indicators of bone<br />

mineralization are <strong>with</strong>in<br />

normal limits<br />

If vitamin D is low, supplement <strong>with</strong> pharmacologic doses of vitamin D3<br />

until it is well <strong>with</strong>in normal limits<br />

While pharmacologic doses of vitamin D are being given, monitor <strong>for</strong><br />

vitamin D toxicity weekly or bimonthly by checking serum Ca level (High<br />

serum Ca may indicate vitamin D toxicity)<br />

• Serum 25 (OH) vitamin D<br />

• Serum calcium (Ca)<br />

• Serum phosphorus (P)<br />

• Serum alkaline phosphatase (Alk<br />

Phos)<br />

64 <strong>Nutrition</strong> <strong>Interventions</strong> <strong>for</strong> <strong>Children</strong> With <strong>Special</strong> <strong>Health</strong> <strong>Care</strong> <strong>Needs</strong><br />

If vitamin D is normal, give up to 2000 IU/day of vitamin D to maintain<br />

stores<br />

If Ca or P is low, and vitamin D is normal, supplement <strong>with</strong> Ca or P. If Ca or<br />

P is low and vitamin D is low, insure DRI levels of Ca and P while vitamin<br />

D is being repleted<br />

If serum Ca, P, and Alk Phos are normal, re-assess 1-2 times per year<br />

STIMULANTS Examples: methylphenidate (Ritalin); dextroamphetamine (Dexedrine, Adderall); pemoline (Cylert)<br />

Dietary intake of all nutrients<br />

is adequate<br />

If diet is low in any nutrient, counsel appropriately. Instruct caregiver(s)<br />

to offer meals be<strong>for</strong>e giving the medication and later in the day when the<br />

medication action is minimal or absent. Collaborate <strong>with</strong> school to make<br />

sure child gets meal or snack be<strong>for</strong>e medication at school, if appropriate<br />

(see Chapter 12)<br />

Assess dietary intake when medication<br />

first prescribed

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