Contents - Max-Planck-Institut für Physik komplexer Systeme
Contents - Max-Planck-Institut für Physik komplexer Systeme
Contents - Max-Planck-Institut für Physik komplexer Systeme
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scalesrangingfromindividualhaircellstotheensembleofhaircellslinedupalongthebasilarmembrane<br />
toinvestigatethenatureofthecochlearamplifier.<br />
Perspectives. Theclosecollaborationbetweenthe mpipksandtheMPI-CBGhasinrecentyearsstimulatedmanynewresearchprojectsbetweenphysicsandbiology.Thegoalofthisresearchistodevelop<br />
quantitativeandtheoreticalapproachestounderstanddynamicprocessesincellsandtissues.Inorderto<br />
expandandfurtherdeveloptheseactivities,the<strong>Max</strong><strong>Planck</strong>SocietyiscurrentlyplanningtocreateaCenterforSystemsBiologyofCellsandTissuesinDresdenthatisjointlyoperatedbythetwoinstitutes.Itis<br />
plannedtohireadditionalresearchgroupleadersaswellasanewdirectoratMPI-CBG.Thenewcenter<br />
willintegratetheoreticalactivitieswithexperimentalists.Anovelresearchactivitythatwillbeattracted<br />
tothenewcenterisimageinformaticswhichcomplementstheexistingactivitiesbetweentheoretical<br />
physicsandbiology. Bycombiningexperimentalbiologywiththeoreticalphysicsandcomputerscience,<br />
theactivitiesinDresdenwillbesignificantlystrengthened.Thiswillalsoallowustomovetowardsnew<br />
challengessuchasthestudyofthedynamicsofcellsandtissuesinthreedimensions.<br />
Cooperations<br />
• <strong>Max</strong><strong>Planck</strong><strong>Institut</strong>eforMolecularCellBiologyandGenetics,Dresden<br />
– CollaborationwiththegroupsofJonathonHoward,AnthonyHymanandStephanGrilloncell<br />
division,cellularpatternformationanddynamics.<br />
– CollaborationwithSuzanneEatonandChristianDahmannonthedynamicorganizationof<br />
epithelia.<br />
– CollaborationwithAndyOatesonthesegmentationofvertebratesthroughoscillatingand<br />
spatio-temporalgeneexpressionpatterns.<br />
– CollaborationswithEwaPaluchonactivecellmechanicsandcelladhesion.<br />
– CollaborationwithMarinoZerialonthedynamicsofendosomaltransportandsignalingnetworksincells.<br />
– CollaborationwithStefanDiezonthecollectivebehaviorsofmolecularmotors.<br />
• <strong>Institut</strong>Curie,Paris<br />
– CollaborationwithJean-FrancoisJoannyandJacquesProstonthephysicsofactivegels,the<br />
dynamicsofthecytoskeletonandcelllocomotion.<br />
– CollaborationwithPascalMartinonthephysicsofmechanosensoryhaircells.<br />
• AMOLF,Amsterdam<br />
– CollaborationwithMarileenDogteromoncytoskeletaldynamics.<br />
• UniversityofGeneva<br />
– CollaborationwithMarcosGonzález-Gaitánonthedynamicsofmorphogensingrowingtissues<br />
andtheirroleingrowthcontrol.<br />
• StanfordUniversity,USA<br />
– CollaborationwithJulieTheriotonoscillationsincelllocomotion.<br />
ResearchGroup:StochasticProcessesinBiophysics<br />
(Head:Dr.BenjaminLindner)<br />
Inmanybiophysicalsystemswefaceafascinatingmixtureofnonlineardynamics,differentkindsoffluctuations,complexsignals,andadaptationprocessesinvolvingmultipletimescales.Inourgroupwestudyselectedproblemsfromneurobiologyandcellbiophysicsintheframeworkofstochasticnonlineardynamics.<br />
Besidesintensecomputersimulationsofsimplifiedbiophysicalmodels,wedevelopnovelanalytical<br />
approachesfortherespectivestatisticsofinteresttogaindeeperinsightsintotheunderlyingprocesses.<br />
Wehavetightcollaborationswithexperimentalcolleaguesandseekforapplicationsofouranalytical<br />
resultstohelpdesigningnewexperimentalparadigms.Specifically,weworkon:<br />
StochasticNeuralActivity. Thegenerationofactionpotentialsbyneurons(nervecells)isinherently<br />
1.8. DepartmentsandResearchGroups 15
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