scaricalo in formato PDF - labogen srl
scaricalo in formato PDF - labogen srl
scaricalo in formato PDF - labogen srl
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ANTIBODIES & VACCINATION 5<br />
124<br />
IgA Antibodies<br />
InvivoGen provides human IgA antibodies that have been generated by recomb<strong>in</strong>ant DNA technology. These IgA antibodies are chimeric monoclonal<br />
antibodies composed of the constant doma<strong>in</strong>s of the human IgA2 molecule and variable regions of different orig<strong>in</strong>s. They have been selected for<br />
their ability to efficiently neutralize the biological activity of selected cytok<strong>in</strong>es and Toll-Like Receptors. The neutraliz<strong>in</strong>g activity of these IgA<br />
antibodies was determ<strong>in</strong>ed us<strong>in</strong>g InvivoGen’s HEK-Blue reporter cells. Some of these IgA antibodies can also be used for flow cytometry.<br />
ANTIBODY REACTIVITY APPLICATIONS QUANTITY CATALOG CODE<br />
Anti-Cytok<strong>in</strong>e IgAs<br />
Anti-hCD40L-hIgA2 Human CD40L Neutralization 100 μg maba-hcd40l<br />
Anti-hIFNa-hIgA2 Human IFN-a Neutralization, FC 100 μg maba-hifna<br />
Anti-hIFNg-hIgA2 Human IFN-g Neutralization 100 μg maba-hifng<br />
Anti-hIL-1b-hIgA2 Human IL-1b Neutralization 100 μg maba-hil1b<br />
Anti-hIL-4-hIgA2 Human IL-4 Neutralization 100 μg maba-hil4<br />
Anti-hIL-6-hIgA2 Human IL-6 Neutralization, FC 100 μg maba-hil6<br />
Anti-hIL-10-hIgA2 Human IL-10 Neutralization 100 μg maba-hil10<br />
Anti-hIL-13-hIgA2 Human IL-13 Neutralization, FC 100 μg maba-hil13<br />
Anti-hIL-18-hIgA2 Human IL-18 Neutralization 100 μg maba-hil18<br />
Anti-hTGFb-hIgA2 Human TGF-b Neutralization 100 μg maba-htgfb<br />
Anti-hTNFa-hIgA2 Human TNF-a Neutralization, FC 100 μg htnfa-mab7<br />
Anti-TLR IgAs<br />
Anti-hCD14-hIgA2 Human CD14 Neutralization of TLR2 and TLR4 , FC 100 μg maba-hcd14<br />
Anti-hTLR2-hIgA2 Human TLR2 Neutralization, FC 100 μg maba2-htlr2<br />
Anti-hTLR3-hIgA2 Human TLR3 FC 100 μg maba-htlr3<br />
Anti-hTLR4-hIgA2 Human TLR4 Neutralization, FC 100 μg maba-htlr4<br />
Anti-hTLR5-hIgA2 Human TLR5 Neutralization, FC 100 μg maba2-htlr5<br />
Control IgA<br />
IgA2 Isotype Control Human IgA2 Control 100 μg maba2-ctrl<br />
Contents and Storage<br />
Each IgA antibody is provided lyophilized from a 0.2 μm filtered solution <strong>in</strong> PBS. Product should be reconstituted <strong>in</strong> sterile water. Lyophilized antibodies are<br />
stable at least six months when stored at -20ºC. Reconstituted IgAs are stable 1 month when stored at 4ºC and 6 months when aliquoted and stored at -<br />
20ºC.<br />
Anti-Human IgA Secondary Antibodies<br />
InvivoGen provides F(ab’)2 fragment secondary antibodies, to avoid<br />
non-specific b<strong>in</strong>d<strong>in</strong>g through Fc receptors, that react with human IgA.<br />
These goat antibodies are conjugated with fluoresce<strong>in</strong> (FITC) or biot<strong>in</strong><br />
for immunodetection or cell sort<strong>in</strong>g applications.<br />
Secondary anti-human IgA antibodies are supplied <strong>in</strong> 1 ml PBS/NaN3.<br />
Store at 4ºC.<br />
www.<strong>in</strong>vivogen.com/iga-antibody<br />
PRODUCT QTY CAT. CODE<br />
Goat F(ab’)2 Anti-Human IgA - Biot<strong>in</strong> 500 μg chiga-biot<br />
Goat F(ab’)2 Anti-Human IgA - FITC 500 μg chiga-fitc<br />
Goat F(ab’)2 IgG Isotype Control - FITC 100 tests cgig-fitc