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INNATE IMMUNITY 3
Ready-Made psiRNA - shRNAs targeting PRR & Related Genes
RNA interference using small interfering RNA (siRNA) or short-hairpin RNA (shRNA) has become a common technique for gene silencing studies.
InvivoGen provides an extensive list of plasmid-based shRNAs that target genes involved in the innate immunity. These plasmid-based shRNAs, called
ready-made psiRNA, are useful to study the role of these target genes in innate immunity.
Description
Ready-made psiRNAs are psiRNA-h7SKGFPzeo-derived plasmids that express high amounts
of shRNAs through the human 7SK RNA Pol III promoter. They feature a GFP::Zeo fusion
gene which confers both reporter and antibiotic resistance activities allowing simple
monitoring of transfection efficiency and selection in both E. coli and mammalian cells.
Contents and Storage
Ready-made psiRNA plasmids are available alone or in a kit.
Each ready-made psiRNA plasmids is provided as 20 μg of lyophilized DNA.
Each ready-made psiRNA kit contains the following components:
- 20 μg of the ready-made psiRNA plasmid of your choice
- 20 μg of a control psiRNA plasmid targeting Luciferase GL3
- 1 vial of LyoComp GT116
- 4 pouches of Fast-Media ® Zeo
Products are shipped at room temperature. Store at -20°C.
GENE NAME SPECIES CAT.
CODE
Toll-Like Receptors (TLRs)
92
TLR1 h, m p 149
TLR2 h, m p 149
TLR3 h, m p 149
TLR4 h, m p 149
TLR5 h, m p 149
TLR6 h, m p 149
TLR7 h, m p 149
TLR8 h, m p 149
TLR9 h, m p 149
TLR10 h p 149
NOD-Like Receptors (NLRs)
IPAF / CARD12 h p 149
NAIP5 / BIRC1E m p 149
NALP1 / CARD7 h p 149
NALP2 h p 149
NALP3 / NLRP3 h, m p 149
NALP12 / Monarch1 h p 149
NOD1 / CARD4 h, m p 149
NOD2 / CARD15 h, m p 149
NOD9 / NLRX1 h, m p 149
RIG-I-Like Receptors (RLRs)
LGP2 / DHX58 h, m p 149
MDA5 / IFIH1 h, m p 149
RIG-I / DDX58 h, m p 149
Other Pathogen Sensors
AIM2 / IFI210 h, m p 148
CLEC9A h, m p 148
DAI / ZBP1 h p 148
DC-SIGN / CD209 h, m p 148
Dectin-1 h, m p 148
IFI16 NEW h, m p 148
GENE NAME SPECIES
Other Pathogen Sensors
MBL2 h p 149
SIGNR1 m p 149
SIGNR2 m p 149
SIGNR3 m p 149
CD14 h, m p 148
CD36 h, m p 148
MD2 NEW h p 149
BCL10 / CLAP h, m p 148
CARD9 h, m p 148
CD44 h, m p 148
DDX3 / DDX3X h p 148
FADD / MORT1 h, m p 148
IKKε / IKBKE / IKK-i h, m p 149
IRAK-1 h, m p 149
IRAK-4 h, m p 149
LRRFIP2 h p 149
NAP1 / AZI2 h, m p 149
Pellino1 / PELI1 h p 149
Pellino2 / PELI2 h p 149
CAT.
CODE
Adaptors
ASC / CARD5 h, m p 148
Cardinal / CARD8 h p 148
IPS-1 / MAVS / VISA h, m p 149
MyD88 h, m p 149
RAC1 h, m p 149
SARM1 h p 149
TICAM1 / TRIF h, m p 149
TICAM2 / TRAM h, m p 149
TIRAP / Mal
Co-receptors
h, m p 149
Signaling Effectors
www.invivogen.com/readymade-psirna
GENE NAME
Signaling Effectors
SPECIES
Pellino3 / PELI3 h, p 149
PKD1 / PKRD1 h p 149
PKR / EIF2AK2 h, m p 149
PRKRA / PACT h, m p 149
RIP1 / RIPK1 h, m p 149
RIP2 / RIPK2 h, m p 149
STING NEW h, m p 149
SUGT1 NEW h p 149
TAK1 / MAP3K7 h, m p 149
TANK h, m p 149
TBK1 / NAK h, m p 149
TRADD h, m p 149
TRAF3 / CAP-1 h, m p 149
TRAF6 / RNF85
Signaling Inhibitors
h, m p 149
A20 / TNFAIP3 h, m p 148
ATF3 h p 148
Bcl-3 h, m p 148
DAK h, m p 148
DUBA m p 148
FLII / Fliih h p 148
IRAK-M h p 149
MULAN / Dublin h, m p 149
PIN1 / DOB h, m p 149
RNF125 / TRAC-1 h, m p 149
RP105 / CD180 h p 149
SIGIRR / TIR8 m p 149
SIKE h, m p 149
ST2 / IL1RL1 / T1 h p 149
Tollip / IL-1RAcPIP h p 149
TRAFD1 / FLN29 h p 149
Triad3A h p 149
CAT.
CODE