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PRODUCT ORIGIN/DESCRIPTION TLR9 Agonists ODN 1668 FITC FITC-labeled CpG ODN - mouse specific, type B EndoFit 10 ng - 10 μg/ml 50 μg tlrl-1668f p 86 ODN 1826 Stimulatory CpG ODN Type B Mouse specific EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg ODN 1826 control Negative control for ODN 1826 EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg www.invivogen.com/innate-immunity-pamps tlrl-1826 tlrl-1826-1 tlrl-1826-5 tlrl-1826c tlrl-1826c-1 tlrl-1826c-5 ODN 1826 Biotin Biotinylated CpG ODN - mouse specific, type B EndoFit 10 ng - 10 μg/ml 50 μg tlrl-1826b p 86 ODN 1826 FITC FITC-labeled CpG ODN - mouse specific, type B EndoFit 10 ng - 10 μg/ml 50 μg tlrl-1826f p 86 ODN 2006 Stimulatory CpG ODN Type B Human specific EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg ODN 2006 control Negative control for ODN 2006 EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg tlrl-2006 tlrl-2006-1 tlrl-2006-5 tlrl-2006c tlrl-2006c-1 tlrl-2006c-5 ODN 2006 Biotin Biotinylated CpG ODN - human specific, type B EndoFit 10 ng - 10 μg/ml 50 μg tlrl-2006b p 86 ODN 2006 FITC FITC-labeled CpG ODN - human specific, type B EndoFit 10 ng - 10 μg/ml 50 μg tlrl-2006f p 86 ODN 2006-G5 Stimulatory CpG ODN Type B Human specific ODN 2007 Stimulatory CpG ODN Type B Bovine / porcine EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg ODN 2007 control Negative control for ODN 2007 EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg ODN 2216 Stimulatory CpG ODN Type A Human specific EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg ODN 2216 control Negative control for ODN 2216 EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg tlrl-2006g5 tlrl-2006g5-1 tlrl-2006g5-5 tlrl-2007 tlrl-2007-1 tlrl-2007-5 tlrl-2007c tlrl-2007c-1 tlrl-2007c-5 tlrl-2216 tlrl-2216-1 tlrl-2216-5 tlrl-2216c tlrl-2216c-1 tlrl-2216c-5 ODN 2216 Biotin Biotinylated CpG ODN - human specific, type A EndoFit 10 ng - 10 μg/ml 50 μg tlrl-2216b p 86 ODN 2216 FITC FITC-labeled CpG ODN - human specific, type A EndoFit 10 ng - 10 μg/ml 50 μg tlrl-2216f p 86 ODN 2336 Stimulatory CpG ODN Type A Human specific EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg ODN 2336 control Negative control for ODN 2336 EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg tlrl-2336 tlrl-2336-1 tlrl-2336-5 tlrl-2336c tlrl-2336c-1 tlrl-2336c-5 ODN 2336 FITC FITC-labeled CpG ODN - human specific, type A EndoFit 10 ng - 10 μg/ml 50 μg tlrl-2336f p 86 ODN 2395 Stimulatory CpG ODN Type C Human / mouse EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg ODN 2395 control Negative control for ODN 2395 EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg tlrl-2395 tlrl-2395-1 tlrl-2395-5 tlrl-2395c tlrl-2395c-1 tlrl-2395c-5 ODN 2395 FITC FITC-labeled CpG ODN - human specific, type C EndoFit 10 ng - 10 μg/ml 50 μg tlrl-2395f p 86 ODN M362 Stimulatory CpG ODN Type C Human / mouse ENDOTOXIN LEVELS WORKING CONCENTRATION QTY EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg ODN M362 control Negative control for ODN M362 EndoFit 5 μM (10 μg/ml) 200 μg 1 mg 5 mg CATALOG CODE tlrl-m362 tlrl-m362-1 tlrl-m362-5 tlrl-m362c tlrl-m362c-1 tlrl-m362c-5 ODN M362 FITC FITC-labeled CpG ODN - human specific, type C EndoFit 10 ng - 10 μg/ml 50 μg tlrl-m362f p 86 INFO p 86 p 86 p 86 p 86 p 86 p 86 p 86 p 86 p 86 p 86 p 86 p 86 p 86 p 86 p 86 79 INNATE IMMUNITY 3
INNATE IMMUNITY 3 ODN 2088 Inhibitory ODN, mouse preferred EndoFit 50 nM - 1 μM 200 μg 1 mg ODN 2088 control Negative control for ODN 2088 EndoFit 50 nM - 1 μM 200 μg 1 mg tlrl-2088 tlrl-2088-1 tlrl-2088c tlrl-2088c-1 ODN 4084-F NEW Class B inhibitory ODN EndoFit 50 nM - 1 μM 200 μg tlrl-4084 p 87 ODN INH-1 NEW Class R inhibitory ODN EndoFit 50 nM - 1 μM 200 μg tlrl-inh1 p 87 ODN INH-47 NEW Negative control for ODN INH-1 EndoFit 50 nM - 1 μM 200 μg tlrl-inh47 p 87 ODN TTAGGG Inhibitory ODN, human preferred EndoFit 50 nM - 1 μM 200 μg tlrl-ttag p 87 1 mg tlrl-ttag-1 80 PRODUCT ORIGIN/DESCRIPTION TLR9 Agonists ENDOTOXIN LEVELS ODN TTAGGG control Negative control for ODN TTAGGG EndoFit 50 nM - 1 μM 200 μg 1 mg tlrl-ttagc tlrl-ttagc-1 G-ODN Inhibitory guanosine-rich ODN EndoFit 50 nM - 1 μM 200 μg tlrl-godn p 87 MDP Muramyldipeptide (L-D isoform, active) EndoFit 10 ng - 10 μg/ml 5 mg tlrl-mdp p 87 MDP control Muramyldipeptide (D-D isoform, inactive) EndoFit 10 ng - 10 μg/ml 5 mg tlrl-mdpc p 88 MDP Biotin Biotinylated Muramyldipeptide EndoFit 100 ng - 10 μg/ml 500 μg tlrl-bmdp p 88 MDP FITC FITC-labeled Muramyldipeptide EndoFit 10 ng - 10 μg/ml 500 μg tlrl-fmdp p 88 MDP Rhodamine Rhodamine-labeled Muramyldipeptide EndoFit 100 ng - 10 μg/ml 500 μg tlrl-rmdp p 88 L18-MDP Muramyldipeptide with a C18 fatty acid chain EndoFit 1 - 100 ng/ml 1 mg tlrl-lmdp p 88 N-Glycolyl-MDP N-glycolylated muramyldipeptide EndoFit 100 ng - 10 μg/ml 5 mg tlrl-gmdp p 88 Murabutide Synthetic derivative of muramyldipeptide EndoFit 10 ng - 1 μg/ml 5 mg tlrl-mbt p 88 Murabutide control Murabutide analog (D isoform, inactive) EndoFit C12-iE-DAP Acylated derivative of iE-DAP EndoFit 10 ng - 1 μg/ml 5 mg tlrl-mbtc p 88 1 ng - 1 μg/ml 1 mg tlrl-c12dap p 87 iE-DAP D-g-Glu-mDAP EndoFit 1 - 100 μg/ml 5 mg tlrl-dap p 87 iE-Lys iE-DAP negative control EndoFit 1 - 100 μg/ml 5 mg tlrl-lys p 87 Tri-DAP L-Ala-g-D-Glu-mDAP EndoFit 100 ng - 10 μg/ml 1 mg tlrl-tdap p 88 Tri-Lys Tri-DAP negative control EndoFit NOD1 Agonists NOD2 Agonists 100 ng - 10 μg/ml 1 mg tlrl-tlys p 88 www.invivogen.com/innate-immunity-pamps WORKING CONCENTRATION QTY CATALOG CODE pCpG Giant CpG-free dcm - giant plasmid EndoFit 5 - 10 μg/ml 1 mg tlrl-cpgg p 86 Salmon sperm DNA TLR9 negative control EndoFit TLR9 Antagonists 5 - 100 μg/ml 50 mg tlrl-sdef p 86 NOD1/2 Agonists M-TriDAP MurNAc-L-Ala-g-D-Glu-mDAP EndoFit 1 - 100 μg/ml 1 mg tlrl-mtd p 88 PGN-ECndi ultrapure Insoluble peptidoglycan from E. coli K12 EndoFit 1 - 5 μg/ml 5 mg tlrl-kipgn p 88 PGN-ECndss ultrapure Soluble sonicated peptidoglycan from E. coli K12 EndoFit 1 - 5 μg/ml 1 mg tlrl-ksspgn p 88 PGN-SAndi ultrapure Insoluble peptidoglycan from S. aureus EndoFit 1 - 5 μg/ml 5 mg tlrl-sipgn p 88 RIG-I/MDA-5 and CDS Agonists 5’ppp-dsRNA NEW 5’triphosphate blunt-end double-stranded RNA EndoFit 300 ng - 1 μg/ml 25 μg 100 μg 5’ppp-dsRNA Control NEW 5’triphosphate blunt-end double-stranded RNA EndoFit 300 ng - 1 μg/ml 25 μg 100 μg Poly(dA:dT) Naked NEW Poly(dA-dT)•poly(dT-dA) EndoFit 1 - 5 μg/ml 200 μg 1 mg tlrl-3prna tlrl-3prna-100 tlrl-3prnac tlrl-3prnac-100 tlrl-patn tlrl-patn-1 Poly(dA:dT)/LyoVec Poly(dA-dT)•poly(dT-dA)/LyoVec complexes EndoFit 1 - 5 μg/ml 100 μg tlrl-patc p 88 Poly(dG:dC) Naked NEW Poly(dG-dC)•poly(dG-dC) EndoFit 1 - 5 μg/ml 200 μg tlrl-pgcn p 88 Poly(dG:dC)/LyoVec NEW Poly(dG-dC)•poly(dG-dC)/LyoVec complexes EndoFit 1 - 5 μg/ml 100 μg tlrl-pgcc p 88 Poly(I:C) (HMW)/LyoVec Poly(I:C) (HMW)/LyoVec complexes EndoFit 100 ng - 1 μg/ml 100 μg tlrl-piclv p 88 1 mg tlrl-piclv-10 Poly(I:C) (LMW)/LyoVec Poly(I:C) (LMW)/LyoVec complexes EndoFit 100 ng - 1 μg/ml 100 μg tlrl-picwlv p 88 1 mg tlrl-picwlv-10 INFO p 87 p 87 p 87 p 88 p 88 p 88
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INNOVATION WITHIN REACH InvivoGen
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CONTENTS AT A GLANCE 1 CELL CULTURE
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4 CYTOKINE SIGNALING TABLE of CONTE
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Mycoplasma Detection & Elimination
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PlasmoTest Contents - HEK-Blue -2
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Primocin - The Antimicrobial Shiel
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SEAP Reporter Gene System Secreted
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HEK-Blue Detection - Real-Time Det
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Blasticidin S Description Blasticid
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LyoVec New formulation LyoVec is
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Poly-Arginine-HA Tagged Reprogrammi
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LENTI-Smart - Lentiviral Vector Pr
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Lentiviral Vector Production and Ce
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Antibody generation using pFUSE-CHI
Page 30 and 31: Engineering Fc regions for altered
Page 32 and 33: pBROAD & pWHERE - Optimized Vector
Page 34 and 35: pSELECT-Tag - Expression of a GFP-,
Page 36 and 37: pVIVO - Expression of Two Genes of
Page 38 and 39: pORF Description pORF plasmids feat
Page 40 and 41: Prom A-List - Human and Rodent Pro
Page 42 and 43: PROMOTER GENE TISSUE DISTRIBUTION S
Page 44 and 45: ChemiComp E. coli ChemiComp E. coli
Page 46 and 47: Fast-Media ® Preparation 1. Empty
Page 48 and 49: RIG-I-like Receptors 54 RLR & RLR-R
Page 50 and 51: Toll-Like Receptors Toll-Like Recep
Page 52 and 53: www.invivogen.com/innate-immunity 5
Page 54 and 55: IPAF and NAIP5 IPAF (NLRC4, CLAN/CA
Page 56 and 57: C-Type Lectin Receptors C-type lect
Page 58 and 59: pUNO pUNO-HA Toll-Like Receptors (T
Page 60 and 61: GENE NAME/ALIASES DESCRIPTION CAT.
Page 62 and 63: pDUO - Gene Associations Features a
Page 64 and 65: pZERO-TLR & pDeNy - Dominant Negati
Page 66 and 67: 293/TLR & 293/NOD Clones 293/TLR Cl
Page 68 and 69: Response of HEK-Blue hTLR2 cells t
Page 70 and 71: Ramos-Blue Cells - NF-kB/AP-1 Repo
Page 72 and 73: MEF Cells C3H/TLR4mut & C3H/WT MEFs
Page 74 and 75: Antibodies for Detection ANTIBODY D
Page 76 and 77: - NF-kB binding site: Nuclear facto
Page 78 and 79: PRODUCT ORIGIN/DESCRIPTION TLR2 Ago
Page 82 and 83: PRODUCT ORIGIN/DESCRIPTION Dectin-1
Page 84 and 85: LPS-PG (Porphyromonas gingivalis) R
Page 86 and 87: • FLA-ST ultrapure was purified b
Page 88 and 89: 1. Zhao H. et al., 2004. Contributi
Page 90 and 91: 1. Hornung V. et al., 2006. 5'-Trip
Page 92 and 93: TLR/NOD Ligand Screening InvivoGen
Page 94 and 95: Signal Transduction Inhibitors Invi
Page 96 and 97: Pepinh-MYD - MyD88 inhibitory pepti
Page 98 and 99: 1. Martinon F,. et al., 2002. The i
Page 100 and 101: Nigericin - NLRP3 Inflammasome Indu
Page 102 and 103: Autophagy is a pathway by which cyt
Page 104 and 105: 4 CYTOKINE SIGNALING Cytokine Genes
Page 106 and 107: Blue Cytokine Reporter Cells Blue
Page 108 and 109: HEK-Blue IFN-a/b Cells - Human Typ
Page 110 and 111: HEK-Blue IL-6 Cells - IL6 Reporter
Page 112 and 113: HEK-Blue IL-1b Cells - IL-1b Repor
Page 114 and 115: HEK-Blue IL-33/IL-1b Cells - IL-33
Page 116 and 117: HEK-Blue CD40L Cells - CD40L Repor
Page 118 and 119: 5 ANTIBODIES & VACCINATION Antibodi
Page 120 and 121: Antibody generation using pFUSE-CHI
Page 122 and 123: Immunoglobulin A The mucosal surfac
Page 124 and 125: IgA Detection and Quantification In
Page 126 and 127: IgG Antibodies InvivoGen offers a s
Page 128 and 129: Mediators? 1. Leroux-Roels G., 2010
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Poly(I:C) Synthetic double-stranded
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pVAC - Induction of Neutralizing An
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CpG-Free DNA CpGs and the Immune Re
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pCpGfree-basic & pCpGfree-promoter
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pCpGfree-siRNA & pCpGfree-siRNADUO
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Custom-Made CpG-Free Genes InvivoGe
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RNA INTERFERENCE 7 psiRNA System I
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RNA INTERFERENCE 7 psiRNA-h7SK - 7S
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RNA INTERFERENCE 7 psiTEST System
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RNA INTERFERENCE 7 Ready-Made psiRN
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RNA INTERFERENCE 7 Custom-Made psiR
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INHIBITORS 8 Inhibitors PRODUCT DES
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INHIBITORS 8 Pattern Recognition Re
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INHIBITORS 8 Triptolide - NF-kB Inh
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INHIBITORS 8 Heat Shock Protein Inh
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9 CUSTOM SERVICES TLR/NOD Ligand Sc
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CUSTOM SERVICES 9 Custom Cloning :
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CUSTOM SERVICES 9 Prices 164 TERMS
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166 PRODUCT (QUANTITY) CAT. CODE PA
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A 17-AAG 17-AAGH2 17-AEP-GA 2-Amino
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- ODN 4084-F - ODN INH-1 - ODN INH-
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ARGENTINA Genbiotech S.R.L. Tel: +5
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