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GENE NAME/ALIASES SPECIES CAT. CODE (plasmid)** IFNAR2 Human, mouse psirna42-(h/m)ifnar2 IKKε / IKBKE / IKK-i Human, mouse psirna42-(h/m)ikke IL1R1 / IL1RA Human psirna42-hil1r1 IPAF / CARD12 Human psirna42-hipaf IPS-1 / MAVS / VISA Human, mouse psirna42-(h/m)ips1 IRAK-1 Human, mouse psirna42-(h/m)irak1 IRAK-4 Human, mouse psirna42-(h/m)irak4 IRAK-M Human psirna42-hirakm IRF1 Human, mouse psirna42-(h/m)irf1 IRF3 Human, mouse psirna42-(h/m)irf3 IRF5 Human, mouse psirna42-(h/m)irf5 IRF7 Human, mouse psirna42-(h/m)irf7 IRF9 Human, mouse psirna42-(h/m)irf9 JAK1 / JAK1A Human, mouse psirna42-(h/m)jak1 KAISO / ZBTB33 Human psirna42-hkaiso KRAS Human, mouse psirna42-(h/m)kras Lamin Human psirna42-hlamin LGP2 / DHX58 Human, mouse psirna42-(h/m)lgp2 LRRFIP2 Human psirna42-hlrrfip2 MBL2 Human psirna42-hmbl2 MBD1 / PCM1 Human psirna42-hmbd1 MD2 NEW Human psirna42-hmd2 MDA-5 / IFIH1 Human, mouse psirna42-(h/m)mda5 MeCP2 Human psirna42-hmecp2 MEKK3 / MAP3K Human, mouse psirna42-(h/m)mekk3 Mincle / CLEC4E Human, mouse psirna42-(h/m)mincle MNDA / PYHIN3 NEW Human psirna42-hmnda MSK1 NEW Human, mouse psirna42-(h/m)msk1 MULAN / MUL1 Human, mouse psirna42-(h/m)mul1 MyD88 Human, mouse psirna42-(h/m)myd88 Naip5 / BIRC1E Mouse psirna42-mnaip5 NALP1 / CARD7 Human psirna42-hnalp1 NALP2 / PAN1 Human psirna42-hnalp2 NALP3 / NLRP3 Human, mouse psirna42-(h/m)nalp3 NALP11 / NLRP11 NEW Human psirna42-hnalp11 NALP12 / Monarch1 Human psirna42-hnalp12 NAP1 / AZI2 Human, mouse psirna42-(h/m)nap1 NOD1 / CARD4 Human, mouse psirna42-(h/m)nod1 NOD2 / CARD15 Human, mouse psirna42-(h/m)nod2 NOD9 / NLRX1 Human, mouse psirna42-(h/m)nod9 p53 Human, mouse psirna42-(h/m)p53 PACT / PRKRA Human, mouse psirna42-(h/m)pact Pannexin 1 / PANX1 Human, mouse psirna42-(h/m)panx1 Pellino 1 / PELI1 Human, mouse psirna42-(h/m)pellino1 Pellino 2 / PELI2 Human, mouse psirna42-(h/m)pellino2 Pellino 3 / PELI3 Human psirna42-hpellino3 PIN1 / DOB Human, mouse psirna42-(h/m)pin1 PKD1 / PRKD1 Human psirna42-hpkd1 PKR / EIFAK2 Human, mouse psirna42-(h/m)pkr RAC1 Human, mouse psirna42-(h/m)rac1 RAGE / AGER Human, mouse psirna42-(h/m)ager RIG-I / DDX58 Human, mouse psirna42-(h/m)rigi RIP1 / RIPK1 Human, mouse psirna42-(h/m)rip1 RIP2 / RIPK2 Human, mouse psirna42-(h/m)rip2 GENE NAME/ALIASES SPECIES CAT. CODE (plasmid)** RNF125 / TRAC-1 Human, mouse psirna42-(h/m)rnf125 RP105 / CD180 Human psirna42-hrp105 S100A8 Mouse psirna42-ms100a8 S100A9 Mouse psirna42-ms100a9 SARM1 Human psirna42-hsarm1 SHIP NEW Human psirna42-hship SIGIRR / TIR8 Mouse psirna42-msigirr SIGNR1 Mouse psirna42-msignr1 SIGNR2 Mouse psirna42-msignr2 SIGNR3 Mouse psirna42-msignr3 SIKE Human, mouse psirna42-(h/m)sike Smad3 Human psirna42-hsmad3 Smad4 Human psirna42-hsmad4 SOCS-1 Human, mouse psirna42-(h/m)socs1 SOCS-3 Human psirna42-hsocs3 ST2 / IL1RL1 / T2 Human psirna42-hst2 STAT1 / STAT91 Human, mouse psirna42-(h/m)stat1 STAT2 / STAT113 Human, mouse psirna42-(h/m)stat2 STAT3 / APRF Human psirna42-hstat3 STING NEW Human, mouse psirna42-(h/m)sting SUGT1 / SGT1 NEW Human psirna42-hsugt1 SUV39H1 / KMTIA Human psirna42-hsuv39h1 TAK1 / MAP3K7 Human, mouse psirna42-(h/m)tak1 TANK Human, mouse psirna42-(h/m)tank TBK1 Human, mouse psirna42-(h/m)tbk1 TBKBP1 / SINTBAD NEW Human psirna42-htbkbp1 TICAM1 / TRIF Human, mouse psirna42-(h/m)ticam1 TICAM2 / TRAM Human, mouse psirna42-(h/m)ticam2 TIFA Human, mouse psirna42-(h/m)tifa TIRAP / MAL Human, mouse psirna42-(h/m)tirap TLR1 / CD281 Human, mouse psirna42-(h/m)tlr1 TLR2 / CD282 Human, mouse psirna42-(h/m)tlr2 TLR3 / CD283 Human, mouse psirna42-(h/m)tlr3 TLR4 / CD284 Human, mouse psirna42-(h/m)tlr4 TLR5 Human, mouse psirna42-(h/m)tlr5 TLR6 / CD286 Human, mouse psirna42-(h/m)tlr6 TLR7 Human, mouse psirna42-(h/m)tlr7 TLR8 / CD288 Human, mouse psirna42-(h/m)tlr8 TLR9 / CD289 Human, mouse psirna42-(h/m)tlr9 TLR10 / CD290 Human psirna42-htlr10 TNFR1 / TNFRSF1A Human psirna42-htnfr1 TNFR2 / TNFRSF1B Human, mouse psirna42-(h/m)tnfr2 Tollip / IL-1RAcP1P Human psirna42-htollip TRADD Human, mouse psirna42-(h/m)tradd TRAF1 NEW Human psirna42-htraf1 TRAF3 / CAP-1 Human, mouse psirna42-(h/m)traf3 TRAF4 NEW Human, mouse psirna42-(h/m)traf4 TRAF6 / RNF85 Human, mouse psirna42-(h/m)traf6 TRAFD1 / FLN29 Human psirna42-htrafd1 Triad3A Human psirna42-htriad3a Tyk2 / JTK1 Human, mouse psirna42-(h/m)tyk2 UBP43 NEW Human, mouse psirna42-(h/m)ubp43 UNC93B1 Human, mouse psirna42-(h/m)unc93 VEGF Human, mouse psirna42-(h/m)vegf ** For the kit catalog code, replace psirna42 by ksirna42 www.invivogen.com/readymade-psirna 149 RNA INTERFERENCE 7
RNA INTERFERENCE 7 Custom-Made psiRNA InvivoGen provides a complete siRNA service to help you speed-up your gene silencing experiments. Just give us the accession number of your gene of interest and we will take care of all the steps, from helping you choose the target sequence on your gene to sequencing the resulting siRNA insert. InvivoGen provides a choice of plasmidic vectors to better suit your needs. ➥ Full Custom Service ➥ Your siRNA vector Ready-to-Use ➥ Cost-effective ➥ Rapid Processing Features and Benefits Choose your siRNA sequence You can either send us your siRNA sequence or, using the siRNA Wizard software, InvivoGen will select the best candidate siRNA sequence for your target gene. Choose your psiRNA Plasmid - psiRNA-h7SK (see page 144) - psiRNA-DUO (see page 145) Choose your selectable marker psiRNA plasmids are available with various selectable markers that confer antibiotic resistance in both E. coli and mammalian cells: - Blasticidin - Zeocin - Hygromycin - GFP::Zeo - Kanamycin / G418 Description Construction of custom-made psiRNA plasmids includes the following: - Selection of the siRNA sequence for the target gene - Synthesis of the siRNA insert oligonucleotides - Cloning of the annealed oligonucleotides in psiRNA - Sequencing of the siRNA insert Contents and Storage Custom-made psiRNA are provided as 20 µg of lyophilized DNA. They can also be provided as a kit that contains in addition - 20 µg of psiRNA-EGFP or psiRNA-LucGL3 as a control - 1 vial of LyoComp GT116 - 4 pouches of the corresponding Fast-Media ® Products are shipped at room temperature. Store at -20°C. 150 www.invivogen.com/custom-cloning Although the siRNA Wizard software can facilitate the selection of functional shRNAs, there is no guarantee that the resulting shRNA will be effective enough for your experiment. Thus it is usually recommended to select 3-5 candidate shRNAs. Furthermore, most journal article reviewers require that gene silencing results be confirmed with a second effective siRNA to a target before an article is accepted for publication. Orders of multiple psiRNA plasmids targeting the same gene will be eligible for a volume discount. PRODUCT QTY CAT. CODE Custom-made psiRNA 20 μg p-custom Custom-made psiRNA Kit 1 kit k-custom
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INNOVATION WITHIN REACH InvivoGen
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CONTENTS AT A GLANCE 1 CELL CULTURE
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4 CYTOKINE SIGNALING TABLE of CONTE
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Mycoplasma Detection & Elimination
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PlasmoTest Contents - HEK-Blue -2
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Primocin - The Antimicrobial Shiel
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SEAP Reporter Gene System Secreted
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HEK-Blue Detection - Real-Time Det
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Blasticidin S Description Blasticid
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LyoVec New formulation LyoVec is
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Poly-Arginine-HA Tagged Reprogrammi
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LENTI-Smart - Lentiviral Vector Pr
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Lentiviral Vector Production and Ce
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Antibody generation using pFUSE-CHI
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Engineering Fc regions for altered
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pBROAD & pWHERE - Optimized Vector
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pSELECT-Tag - Expression of a GFP-,
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pVIVO - Expression of Two Genes of
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pORF Description pORF plasmids feat
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Prom A-List - Human and Rodent Pro
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PROMOTER GENE TISSUE DISTRIBUTION S
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ChemiComp E. coli ChemiComp E. coli
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Fast-Media ® Preparation 1. Empty
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RIG-I-like Receptors 54 RLR & RLR-R
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Toll-Like Receptors Toll-Like Recep
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www.invivogen.com/innate-immunity 5
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IPAF and NAIP5 IPAF (NLRC4, CLAN/CA
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C-Type Lectin Receptors C-type lect
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pUNO pUNO-HA Toll-Like Receptors (T
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GENE NAME/ALIASES DESCRIPTION CAT.
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pDUO - Gene Associations Features a
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pZERO-TLR & pDeNy - Dominant Negati
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293/TLR & 293/NOD Clones 293/TLR Cl
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Response of HEK-Blue hTLR2 cells t
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Ramos-Blue Cells - NF-kB/AP-1 Repo
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MEF Cells C3H/TLR4mut & C3H/WT MEFs
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Antibodies for Detection ANTIBODY D
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- NF-kB binding site: Nuclear facto
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PRODUCT ORIGIN/DESCRIPTION TLR2 Ago
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PRODUCT ORIGIN/DESCRIPTION TLR9 Ago
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PRODUCT ORIGIN/DESCRIPTION Dectin-1
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LPS-PG (Porphyromonas gingivalis) R
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• FLA-ST ultrapure was purified b
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1. Zhao H. et al., 2004. Contributi
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1. Hornung V. et al., 2006. 5'-Trip
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TLR/NOD Ligand Screening InvivoGen
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Signal Transduction Inhibitors Invi
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Pepinh-MYD - MyD88 inhibitory pepti
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1. Martinon F,. et al., 2002. The i
Page 100 and 101: Nigericin - NLRP3 Inflammasome Indu
Page 102 and 103: Autophagy is a pathway by which cyt
Page 104 and 105: 4 CYTOKINE SIGNALING Cytokine Genes
Page 106 and 107: Blue Cytokine Reporter Cells Blue
Page 108 and 109: HEK-Blue IFN-a/b Cells - Human Typ
Page 110 and 111: HEK-Blue IL-6 Cells - IL6 Reporter
Page 112 and 113: HEK-Blue IL-1b Cells - IL-1b Repor
Page 114 and 115: HEK-Blue IL-33/IL-1b Cells - IL-33
Page 116 and 117: HEK-Blue CD40L Cells - CD40L Repor
Page 118 and 119: 5 ANTIBODIES & VACCINATION Antibodi
Page 120 and 121: Antibody generation using pFUSE-CHI
Page 122 and 123: Immunoglobulin A The mucosal surfac
Page 124 and 125: IgA Detection and Quantification In
Page 126 and 127: IgG Antibodies InvivoGen offers a s
Page 128 and 129: Mediators? 1. Leroux-Roels G., 2010
Page 130 and 131: Poly(I:C) Synthetic double-stranded
Page 132 and 133: pVAC - Induction of Neutralizing An
Page 134 and 135: CpG-Free DNA CpGs and the Immune Re
Page 136 and 137: pCpGfree-basic & pCpGfree-promoter
Page 138 and 139: pCpGfree-siRNA & pCpGfree-siRNADUO
Page 140 and 141: Custom-Made CpG-Free Genes InvivoGe
Page 143 and 144: RNA INTERFERENCE 7 psiRNA System I
Page 145 and 146: RNA INTERFERENCE 7 psiRNA-h7SK - 7S
Page 147 and 148: RNA INTERFERENCE 7 psiTEST System
Page 149: RNA INTERFERENCE 7 Ready-Made psiRN
Page 153 and 154: INHIBITORS 8 Inhibitors PRODUCT DES
Page 155 and 156: INHIBITORS 8 Pattern Recognition Re
Page 157 and 158: INHIBITORS 8 Triptolide - NF-kB Inh
Page 159 and 160: INHIBITORS 8 Heat Shock Protein Inh
Page 161 and 162: 9 CUSTOM SERVICES TLR/NOD Ligand Sc
Page 163 and 164: CUSTOM SERVICES 9 Custom Cloning :
Page 165 and 166: CUSTOM SERVICES 9 Prices 164 TERMS
Page 167 and 168: 166 PRODUCT (QUANTITY) CAT. CODE PA
Page 173 and 174: A 17-AAG 17-AAGH2 17-AEP-GA 2-Amino
Page 175 and 176: - ODN 4084-F - ODN INH-1 - ODN INH-
Page 177 and 178: ARGENTINA Genbiotech S.R.L. Tel: +5
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