scaricalo in formato PDF - labogen srl

Recommendations

Info

Mediators? 1. Leroux-Roels G., 2010. Unmet needs in modern vaccinology adjuvants to imporve the immune response. Vaccine. 28S(3):C25-3. 2. Li H. et al., 2008. Cutting edge: Inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J Immunol. 181(1):17-21. 3. Marrack P. et al., 2009. Towards an understanding of the adjuvant action of aluminium. Nat Rev Immunol. 9(4):287-93. 4. Ott G. et al., 1995. MF59. Design and evaluation of a safe and potent adjuvant for human vaccines. Pharm Biotechnol 6: 277-96. 5. Steinhagen F. et al., 2010. TLR-based immune adjuvants. Vaccine [Epub ahead of print]. 6. Mbow ML. et al., 2010. New adjuvants for human vaccines. Curr Opin Immunol. 22(3):411-6. 7. Didierlaurent A. ,et al., 2009. AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity. J Immunol 183(10): 6186-97. 8. Coffman R. et al., 2010. Vaccine adjuvants: Putting innate immunity to work. Immunity 33(4):492-503. 9. Huleatt J. et al., 2007.Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity. Vaccine 25(4): 763-75. 10. Mizel S. & Bates JT., 2010. Flagellin as an adjuvant: Cellular mechanisms and potential. J Immunol. 175(10):5677- 82. 11. Kobayashi H. et al., 1999. Immunostimulatory DNA pre-priming: a novel approach for prolonged Th1-biased immunity. Cell Immunol 198(1): 69-75. 12. Tighe H. et al., 2000. Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity. J Allergy Clin Immunol 106: 124-34. 13. Girardin S. et al., 2003. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem. 278(11):8869- 72. 14. Siegrist C. et al., 2004. Co-administration of CpG oligonucleotides enhances the late affinity maturation process of human anti-hepatitis B vaccine response. Vaccine 23(5): 615-22. 15. Kim S. et al., 2000. Effect of immunological adjuvant combinations on the antibody and T-cell response to vaccination with MUC1-KLH and GD3-KLH conjugates. Vaccine 19: 530-7. www.invivogen.com/vaccine-adjuvants 127 ANTIBODIES & VACCINATION 5
ANTIBODIES & VACCINATION 5 Vaccine Adjuvants NEW InvivoGen provides different classes of vaccine adjuvants that are either already approved for use in human vaccination, such as alum, or under investigation such as the TLR agonists gardiquimod and CpG oligonucleotides. InvivoGen adjuvants are VacciGrade (preclinical grade). They are prepared under strict aseptic conditions and tested for the presence of endotoxins. They are sterile and their endotoxin level is
Page 2 and 3:
INNOVATION WITHIN REACH InvivoGen
Page 4 and 5:
CONTENTS AT A GLANCE 1 CELL CULTURE
Page 6 and 7:
4 CYTOKINE SIGNALING TABLE of CONTE
Page 8 and 9:
Mycoplasma Detection & Elimination
Page 10 and 11:
PlasmoTest Contents - HEK-Blue -2
Page 12 and 13:
Primocin - The Antimicrobial Shiel
Page 14 and 15:
SEAP Reporter Gene System Secreted
Page 16 and 17:
HEK-Blue Detection - Real-Time Det
Page 18 and 19:
Blasticidin S Description Blasticid
Page 20 and 21:
LyoVec New formulation LyoVec is
Page 22 and 23:
Poly-Arginine-HA Tagged Reprogrammi
Page 24 and 25:
LENTI-Smart - Lentiviral Vector Pr
Page 26 and 27:
Lentiviral Vector Production and Ce
Page 28 and 29:
Antibody generation using pFUSE-CHI
Page 30 and 31:
Engineering Fc regions for altered
Page 32 and 33:
pBROAD & pWHERE - Optimized Vector
Page 34 and 35:
pSELECT-Tag - Expression of a GFP-,
Page 36 and 37:
pVIVO - Expression of Two Genes of
Page 38 and 39:
pORF Description pORF plasmids feat
Page 40 and 41:
Prom A-List - Human and Rodent Pro
Page 42 and 43:
PROMOTER GENE TISSUE DISTRIBUTION S
Page 44 and 45:
ChemiComp E. coli ChemiComp E. coli
Page 46 and 47:
Fast-Media ® Preparation 1. Empty
Page 48 and 49:
RIG-I-like Receptors 54 RLR & RLR-R
Page 50 and 51:
Toll-Like Receptors Toll-Like Recep
Page 52 and 53:
www.invivogen.com/innate-immunity 5
Page 54 and 55:
IPAF and NAIP5 IPAF (NLRC4, CLAN/CA
Page 56 and 57:
C-Type Lectin Receptors C-type lect
Page 58 and 59:
pUNO pUNO-HA Toll-Like Receptors (T
Page 60 and 61:
GENE NAME/ALIASES DESCRIPTION CAT.
Page 62 and 63:
pDUO - Gene Associations Features a
Page 64 and 65:
pZERO-TLR & pDeNy - Dominant Negati
Page 66 and 67:
293/TLR & 293/NOD Clones 293/TLR Cl
Page 68 and 69:
Response of HEK-Blue hTLR2 cells t
Page 70 and 71:
Ramos-Blue Cells - NF-kB/AP-1 Repo
Page 72 and 73:
MEF Cells C3H/TLR4mut & C3H/WT MEFs
Page 74 and 75:
Antibodies for Detection ANTIBODY D
Page 76 and 77:
- NF-kB binding site: Nuclear facto
Page 78 and 79: PRODUCT ORIGIN/DESCRIPTION TLR2 Ago
Page 80 and 81: PRODUCT ORIGIN/DESCRIPTION TLR9 Ago
Page 82 and 83: PRODUCT ORIGIN/DESCRIPTION Dectin-1
Page 84 and 85: LPS-PG (Porphyromonas gingivalis) R
Page 86 and 87: • FLA-ST ultrapure was purified b
Page 88 and 89: 1. Zhao H. et al., 2004. Contributi
Page 90 and 91: 1. Hornung V. et al., 2006. 5'-Trip
Page 92 and 93: TLR/NOD Ligand Screening InvivoGen
Page 94 and 95: Signal Transduction Inhibitors Invi
Page 96 and 97: Pepinh-MYD - MyD88 inhibitory pepti
Page 98 and 99: 1. Martinon F,. et al., 2002. The i
Page 100 and 101: Nigericin - NLRP3 Inflammasome Indu
Page 102 and 103: Autophagy is a pathway by which cyt
Page 104 and 105: 4 CYTOKINE SIGNALING Cytokine Genes
Page 106 and 107: Blue Cytokine Reporter Cells Blue
Page 108 and 109: HEK-Blue IFN-a/b Cells - Human Typ
Page 110 and 111: HEK-Blue IL-6 Cells - IL6 Reporter
Page 112 and 113: HEK-Blue IL-1b Cells - IL-1b Repor
Page 114 and 115: HEK-Blue IL-33/IL-1b Cells - IL-33
Page 116 and 117: HEK-Blue CD40L Cells - CD40L Repor
Page 118 and 119: 5 ANTIBODIES & VACCINATION Antibodi
Page 120 and 121: Antibody generation using pFUSE-CHI
Page 122 and 123: Immunoglobulin A The mucosal surfac
Page 124 and 125: IgA Detection and Quantification In
Page 126 and 127: IgG Antibodies InvivoGen offers a s
Page 130 and 131: Poly(I:C) Synthetic double-stranded
Page 132 and 133: pVAC - Induction of Neutralizing An
Page 134 and 135: CpG-Free DNA CpGs and the Immune Re
Page 136 and 137: pCpGfree-basic & pCpGfree-promoter
Page 138 and 139: pCpGfree-siRNA & pCpGfree-siRNADUO
Page 140 and 141: Custom-Made CpG-Free Genes InvivoGe
Page 143 and 144: RNA INTERFERENCE 7 psiRNA System I
Page 145 and 146: RNA INTERFERENCE 7 psiRNA-h7SK - 7S
Page 147 and 148: RNA INTERFERENCE 7 psiTEST System
Page 149 and 150: RNA INTERFERENCE 7 Ready-Made psiRN
Page 151 and 152: RNA INTERFERENCE 7 Custom-Made psiR
Page 153 and 154: INHIBITORS 8 Inhibitors PRODUCT DES
Page 155 and 156: INHIBITORS 8 Pattern Recognition Re
Page 157 and 158: INHIBITORS 8 Triptolide - NF-kB Inh
Page 159 and 160: INHIBITORS 8 Heat Shock Protein Inh
Page 161 and 162: 9 CUSTOM SERVICES TLR/NOD Ligand Sc
Page 163 and 164: CUSTOM SERVICES 9 Custom Cloning :
Page 165 and 166: CUSTOM SERVICES 9 Prices 164 TERMS
Page 167 and 168: 166 PRODUCT (QUANTITY) CAT. CODE PA
Page 173 and 174: A 17-AAG 17-AAGH2 17-AEP-GA 2-Amino
Page 175 and 176: - ODN 4084-F - ODN INH-1 - ODN INH-
Page 177 and 178: ARGENTINA Genbiotech S.R.L. Tel: +5
show all

scaricalo in formato PDF - labogen srl

Create successful ePaper yourself

Delete template?

Save as template?