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INHIBITORS 8
Inhibitors
PRODUCT DESCRIPTION
Pattern Recognition Receptor (PRR) Signaling Inhibitors
BX795 TBK1/IKKε and PDK1 inhibitor 10 nM - 1 μM 5 mg tlrl-bx7 p 154
Chloroquine Endosomal acidification inhibitor 10 μM 250 mg tlrl-chq p 154
CLI-095 TLR4 signaling inhibitor 50 nM - 1 μM 1 mg tlrl-cli95 p 154
Cyclosporin A NEW Calcineurin inhibitor 50 nM - 1.5 μM 100 mg tlrl-cyca p 154
Gefitinib (Iressa) NEW RIP2 tyrosine kinase inhibitor 10 μM 10 mg tlrl-gef p 154
OxPAPC TLR2 and TLR4 inhibitor 30 μg/ml 1 mg tlrl-oxp1 p 154
Pepinh-MYD MyD88 inhibitory peptide 5 - 100 μM 2 mg tlrl-pimyd p 154
Pepinh-TRIF TRIF inhibitory peptide 5 - 100 μM 2 mg tlrl-pitrif p 154
Polymyxin B LPS-induced TLR4 activation inhibitor 10 μg/ml 100 mg tlrl-pmb p 154
Rapamycin (Sirolimus) mTOR inhibitor 10-100 nM 5 mg tlrl-rap p 154
Z-VAD-FMK Pan-caspase Inhibitor 10 μg/ml (20 μM) 1 mg tlrl-vad p 154
Cytokine Receptor Inhibitor
SB431542 TGF-b receptor inhibitor 2 μM 5 mg inh-sb43 p 155
Ion Channel Inhibitors
Bafilomycin A1 V-ATPase inhibitor 0.1 - 1 μM 10 μg tlrl-baf p 155
Glybenclamide (glyburide) ATP-dependent K+ channel inhibitor 25 μg/ml 1 g tlrl-gly p 155
Nuclear Export Inhibitor
WORKING
CONCENTRATION
QUANTITY
CATALOG
CODE
Leptomycin B NEW Nuclear export inhibitor 50 - 200 nM 5 μg tlrl-lep p 155
NF-kB Activation Inhibitors
Bay11-7082 IkB-a inhibitor 1 - 10 μM 10 mg tlrl-b82 p 155
Celastrol NF-kB inhibitor 2.5 - 10 μM 1 mg ant-cls p 155
Triptolide NF-kB activation inhibitor 10 - 100 nM 1 mg ant-tpl p 156
Mitogen-Activated Protein (MAP) Kinase Inhibitors
PD98059 MAP kinase kinase inhibitor 50 - 100 μM 10 mg tlrl-pd98 p 156
PD0325901 MEK inhibitor 0.5 μM 2 mg inh-pd32 p 156
SB203580 p38 MAP kinase inhibitor 1 - 20 μM 5 mg tlrl-sb20 p 156
SP600125 JNK inhibitor 10 - 500 μM 10 mg tlrl-sp60 p 156
U0126 MEK1-MEK2 inhibitor 10 - 50 μM 5 mg tlrl-u0126 p 156
Phosphatidylinositol 3-Kinase Inhibitors
3-Methyladenine PI3K inhibitor 5 mM 50 mg tlrl-3ma p 156
LY294002 PI3K inhibitor 50 - 100 μM 5 mg tlrl-ly29 p 156
Wortmannin PI3K inhibitor 0.1 - 2.5 μM 5 mg tlrl-wtm p 156
152 www.invivogen.com/inhibitors
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