Docetaxel with prednisone or prednisolone for the treatment of ...
Docetaxel with prednisone or prednisolone for the treatment of ...
Docetaxel with prednisone or prednisolone for the treatment of ...
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Study details and Participant details Intervention details Results Conclusion and<br />
design comments<br />
51 who did not have post-baseline QoL assessments tended<br />
to have a po<strong>or</strong>er perf<strong>or</strong>mance status and lower QOL at<br />
baseline<br />
Differencea p-Value<br />
Blinding<br />
Outcome<br />
assess<strong>or</strong>: No<br />
Carer: No<br />
Patient: No<br />
Success<br />
assessed: NA<br />
80% Follow-up:<br />
Yes<br />
FLIC: total –4.34 0.12<br />
Symptom distress: total 0.05 0.96<br />
Sexual and urological function: total 0.08 0.89<br />
Problems in daily life –1.25 0.20<br />
Impact <strong>of</strong> pain –1.87 0.38<br />
FLIC: physical well–being –1.90 0.29<br />
FLIC: emotional state –1.42 0.04<br />
FLIC: family disruption –0.93 0.02<br />
FLIC: pain from cancer 0.35 0.26<br />
FLIC: pain interferes –0.18 0.43<br />
Symptom distress: pain, how <strong>of</strong>ten –0.30 0.06<br />
Symptom distress: pain, how severe –0.28 0.03<br />
Symptom distress: appetite 0.08 0.59<br />
Symptom distress: fatigue –0.06 0.68<br />
© Queen’s Printer and Controller <strong>of</strong> HMSO 2007. All rights reserved.<br />
a Negative values favour I, positive values favour C.<br />
Discontinuations: Not rep<strong>or</strong>ted<br />
Number <strong>of</strong> cycles: median <strong>of</strong> 5 cycles <strong>of</strong> mitoxantrone<br />
Health Technology Assessment 2007; Vol. 11: No. 2<br />
151