credits bmbl December 7 '06.doc - Central Michigan University

Table of Contents
Biosafety in Microbiological and Biomedical Laboratories (BMBL)
5th Edition
Title Page 1
Table of Contents 2
Forward 5
SECTION I: Introduction 18
SECTION II: Biological Risk Assessment 25
TABLE 1. Classification of Infectious Microorganisms
By Risk Group 26
SECTION III: Principles of Biosafety 36
SECTION IV: Laboratory Biosafety Level Criteria 44
Table 1. Summary of Recommended Biosafety Levels for
Infectious Agents 74
SECTION V: Vertebrate Animal Biosafety Level Criteria, for
Vivarium Research Facilities 75
Table 1. Summary of Recommended Biosafety Levels for
Activities in Which Experimentally or Naturally
Infected Vertebrate Animals Are Used. 119
SECTION VI: Principles of Laboratory Biosecurity 120
SECTION VII: Occupational Health and Immunoprophylaxis 130
SECTION VIII: Agent Summary Statements 138
SECTION VIII-A: Bacterial Agents 138
SECTION VIII-B: Fungal Agents 185
SECTION VIII-C: Parasitic Agents 197
SECTION VIII-D: Rickettsial Agents 209
SECTION VIII-E: Viral Agents 215
SECTION VIII-F: Arboviruses and Related Zoonotic Viruses 244
Table 2. Explanation of Symbols Used in Table 2 to
Define Basis for Assignment of Viruses to Biosafety
Levels 246
Table 3. Vaccine Strains of BSL-3 AND -4 Viruses
That May Be Handled AS BSL-2 247
Table 1. Alphabetic Listing of 597 Arboviruses and
Hemorrhagic Fever Viruses 261
SECTION VIII-G: Toxin Agents 285