credits bmbl December 7 '06.doc - Central Michigan University

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Appendix D acceptance of the facility for use. Consult your facility engineer for testing and commissioning details. IV. PATHOGENS OF VETERINARY SIGNIFICANCE Some pathogens of livestock, poultry and fish may require special laboratory design, operation, and containment features. This may be BSL-3, BSL-3 plus enhancements or BSL-4 and for animals ABSL-2, ABSL-3 or BSL-3-Ag. The importation, possession, or use of the following agents is prohibited or restricted by law or by USDA regulations or administrative policies. This Appendix does not cover manipulation of diagnostic samples; however, if a foreign animal disease agent is suspected, samples should be immediately forwarded to a USDA diagnostic laboratory (The National Veterinary Services Laboratories, Ames, IA or the Foreign Animal Disease Diagnostic Laboratory, Plum Island, NY). A list of agents and their requirements follows. African horse sickness virus a,b a, b, c African swine fever virus Lumpy Akabane virus b Avian influenza virus Menangle a, b, c (highly pathogenic) Bacillus anthracis a, b Besnoitia besnoiti Bluetongue virus (exotic) a, b Borna disease virus Bovine infectious petechial fever agent Bovine spongiform encephalopathy prion b Brucella abortus a, b Brucella melitensis a, b Brucella suis a, b Burkholderia mallei/Pseudomonas mallei (Glanders) a, b Burkholderia pseudomallei a, b Louping ill virus a skin disease virus a, b, c Malignant catarrhal fever virus (exotic strains or alcelaphine herpesvirus type 1) b virus b Mycobacterium bovis Mycoplasma agalactiae Mycoplasma mycoides subsp. mycoides, (small a, b, c colony type) Mycoplasma capricolum a, b, c Nairobi sheep disease virus (Ganjam virus) Newcastle disease virus a, b, c (velogenic strains) Nipah virus a, b, d Peste des petits ruminants virus a, b, c (plague of small ruminants) a, b, c Rift Valley fever virus Rinderpest virus a, b, c Sheep pox virus a, b 370
Appendix D Camelpox virus b a, b, c Classical swine fever virus Swine Coccidioides immitis b Cochliomyia hominivorax (Screwworm) Coxiella burnetti (Q fever) b Ephemeral fever virus Ehrlichia (Cowdria) ruminantium (heartwater) b Eastern equine encephalitis virus a, b a, b, c, Foot and mouth disease virus Trypanosoma Francisella tularensis b Goat pox a, b Hemorrhagic disease of rabbits virus a, b, d Hendra virus Venezuelan Histoplasma (Zymonema) farciminosum Infectious salmon anemia virus Japanese encephalitis virus a, b Spring Viremia of Carp virus vesicular disease virus b Teschen disease virus a Theileria annulata Theileria lawrencei Theileria bovis Theileria hirci Trypanosoma brucei congolense Trypanosoma equiperdum (dourine) Trypanosoma evansi Trypanosoma vivax equine encephalomyelitis virus a, b Vesicular exanthema virus Vesicular stomatitis virus (exotic) a, b Wesselsbron disease virus Notes: a Export license required by Deptartment of Commerce (See http://www.bis.doc.gov/index.htm). b Agents regulated as Select Agents under the Bioterrorism Act of 2002. Possession of these agents requires registration with either the CDC or APHIS and a permit issued for interstate movement or importation by APHIS- VS. Most require BSL-3/ABSL-3 or higher containment (enhancements as described in this Appendix or on a case-by-case basis as determined by APHIS-VS). c Requires BSL-3-Ag containment for all work with the agent in loose-housed animals. d Requires BSL-4 containment for all work with the agent. A USDA/APHIS import or interstate movement permit is required to obtain any infectious agent of animals or plants that is regulated by USDA/APHIS. An import permit is also required to import any livestock or poultry product such as blood, serum, or other tissues. 371
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Biosafety in Microbiological and Bi
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SECTION VIII-H: Prion Diseases 299
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Forward Biosafety in Microbiologica
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Editors: L. Casey Chosewood, MD Dir
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Guest Editors: Matthew J. Arduino,
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Charles B. Millard, PhD Lieutenant
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Robert Bull Karen B. Byers Jane Cap
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Thomas L. Miller Douglas M. Moore M
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Robert Yarchoan Uri Yokel Lisa Youn
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Introduction laboratories chose not
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Introduction RISK CRITERIA FOR ESTA
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Introduction BMBL includes an impor
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Section II Biological Risk Assessme
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Biological Risk Assessment informat
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Biological Risk Assessment The NIH
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Biological Risk Assessment effectiv
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Biological Risk Assessment Third, m
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Biological Risk Assessment 14. Oxma
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Principles of Biosafety Safety equi
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Principles of Biosafety Often an in
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Principles of Biosafety Four standa
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Principles of Biosafety 4. Centers
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Laboratory Biosafety Level Criteria
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Section V Vertebrate Animal Biosafe
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Vertebrate Animal Biosafety Level C
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TABLE 1 SUMMARY OF RECOMMENDED BIOS
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Principles of Laboratory Biosecurit
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Occupational Health and Immunoproph
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Agent Summary Statements - Bacteria
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• Section VIII-B: Fungal Agents A
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Agent Summary Statements - Fungal A
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• Section VIII-C: Parasitic Agent
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Agent Summary Statements - Parasiti
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• Section VIII-D: Rickettsial Age
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Agent Summary Statements - Ricketts
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Agent Summary Statements - Ricketts
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• Section VIII-E: Viral Agents Ag
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Agent Summary Statements - Viral Ag
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• Section VIII-G: Toxin Agents Se
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Agent Summary Statements - Toxins A
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• Section VIII-H: Prion Diseases
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Appendix A Proper maintenance of ca
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Appendix A declined. However, in ma
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Appendix A It is possible to exhaus
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Appendix A 4. The Class II, Type A2
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Appendix A prohibited. Furthermore,
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Appendix A plastic wrappers, pipett
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Page 321 and 322: Appendix A SECTION VI FACILITY AND
Page 323 and 324: Appendix A Development of Containme
Page 325 and 326: Appendix A C. Airflow Smoke Pattern
Page 327 and 328: Appendix A TABLES Table 1. Selectio
Page 329 and 330: Appendix A Table 3. Field Performan
Page 331 and 332: Appendix A FIGURES Figure 1. HEPA f
Page 333 and 334: Appendix A Figure 3. The Class II,
Page 335 and 336: Appendix A Figure 5B. The Class II,
Page 337 and 338: Appendix A Figure 8. The Class III
Page 339 and 340: Appendix A Figure 9B. The vertical
Page 341 and 342: Appendix A Figure 11. A typical lay
Page 343 and 344: Appendix A REFERENCES 1. Centers fo
Page 345 and 346: Appendix B Decontamination and Disi
Page 347 and 348: Appendix B surfaces are contaminate
Page 349 and 350: Appendix B TABLE 1 DESCENDING ORDER
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Page 353 and 354: Appendix B d The effectiveness of a
Page 355 and 356: Appendix C Transportation of Infect
Page 357 and 358: Appendix C 1600 Clifton Road, N.E.,
Page 359 and 360: Appendix C disease in humans or in
Page 361 and 362: Appendix C Biological specimen, Cat
Page 363 and 364: Appendix D Agriculture Pathogen Bio
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Page 367 and 368: Appendix D 14. Pathological inciner
Page 369: Appendix D Wastes and other materia
Page 373 and 374: Appendix D SPECIAL ISSUES The impor
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Page 377 and 378: Appendix D depression, anorexia, an
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Page 381 and 382: Appendix D five day period of conta
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Page 391 and 392: Appendix D Spring Viremia of Carp V
Page 393 and 394: Appendix D REFERENCES 1. Hess WR. A
Page 395 and 396: Appendix D 37. Alexander DJ. Newcas
Page 397 and 398: Appendix E Arthropod Containment Gu
Page 399 and 400: Appendix F Select Agents and Toxins
Page 401 and 402: Appendix G IPM issues and requireme
Page 403 and 404: Appendix H Working with Human, NHP
Page 405 and 406: Appendix I Guidelines for Work with
Page 407 and 408: decontaminated periodically, for ex
Page 409 and 410: 0.25N, and/or sodium hypochlorite (
Page 411 and 412: k Irradiation causes a dose-depende
Page 413 and 414: 7. Morin R, Kozlovac J. Biological
Page 415 and 416: Appendix J NIH Oversight of Researc
Page 417 and 418: Appendix K Resources for Informatio
Page 419 and 420: Appendix K E-mail: http://www2.gsu.
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Appendix K and http://www.who.int/c
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Appendix L HEPA High Efficiency Par
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