14th ICID - Poster Abstracts - International Society for Infectious ...

When citing these abstracts please use the following reference:
Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number.
Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1
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Final Abstract Number: 76.030
Session: Emerging Infectious Diseases
Date: Friday, March 12, 2010
Time: 12:30-13:30
Room: Poster & Exhibition Area/Ground Level
Type: Poster Presentation
Dengue fever in a Southeastern region of Brazil. Ten years period (1997-2007) clinical and
epidemiological retrospective study.
V. Ribeiro 1 , R. Angerami 2 , M. Resende 1 , M. H. Pavan 1 , E. Hoehne 3 , V. Souza 4 , C. Souza 4 , M.
Souza 4 , M. Wonhrathi 4 , S. Cadogan 4 , F. Aoki 1
1 Discilpine of Infectious Diseases, State Univeristy of Campinas, Campinas, SP, Brazil,
2 Campinas, SP, Brazil, 3 Department of Preventive Medicine, State University of Campinas ,
Campinas, SP, Brazil, 4 Department of Health of Sumaré, Sumaré, SP, Brazil
Background: Dengue is viral endemic/epidemic mosquito-borne disease, with worldwide
distribution, and with increasing incidence in many tropical countries. Clinically, ranges from
asymptomatic or mild cases to severe forms. It is estimated that annually more than 50 millions of
infections, 500.000 cases of dengue hemorrhagic fever (DHF), and 22.000 deaths occurs
worldwide. In Brazil, where more than 60% of notified cases of dengue in the American continent
occurs and there are circulating the serotypes 1 (DEN1), 2 (DEN2), and 3 (DEN3), there have
been seen annually successive epidemics and an increasing number of hemorrhagic dengue
fever cases.
Methods: Retrospective study based on data collected from epidemiological files of confirmed
dengue cases notified during epidemics occurred in the municipality of Sumaré, São Paulo State,
Brazil, in the period between 1997 and 2007.
Results: There were analyzed a total of 4818 cases (56% female; median age 31 years [range 0-
89 years]); of them, 4028 (83.6%) were notified during an epidemic in 2007.A reduced number of
studied cases were distributed in the other years: 1997 (1.1%); 2002 (5.2%); 2003(2.3%);
2005(0.8%); 2006(6.9%).The most frequent clinical signs were fever (97%), headache(94%),
myalgia(87%), malaise(85%), ocular pain(78%), nausea/vomiting(69%), arthralgia(68%),
rash(42%), diarrhea(36%). Petechiae(10%), epistaxis(6%), gingival hemorrhage(3%),
hematuria(1%), vaginal bleeding(1%), gastrointestinal bleeding(0,37%) were the spontaneous
hemorrhagic phenomena observed; tourniquet test was positive in 9% of examined cases.
Among the warning signs associated with severity, abdominal pain(33%), arterial
hypotension(4%), hepatomegaly with pain(2%), and neurological manifestations(2%) were the
most observed. The majority of cases (99.17%) were classified as dengue classic; while a small
proportion of dengue hemorrhagic fever [DHF] (0.13%) and dengue with complications (0.13%),
there was not observed dengue shock syndrome [SSD] cases.
Conclusion: Since its reemergence in the beginning of 1980’s, dengue remains one of the most
important public health problem in Brazil. In the present study the number of DHF was not
significant. One possible explanation could be associated to the difficulty of fulfill the WHO
criteria. As observed in the present study, during an epidemic as occurred in 2007 the increased
number of symptomatic suspected cases usually impacts markedly in the whole health
system.