14th ICID - Poster Abstracts - International Society for Infectious ...

When citing these abstracts please use the following reference:
Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number.
Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1
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Final Abstract Number: 76.005
Session: Emerging Infectious Diseases
Date: Friday, March 12, 2010
Time: 12:30-13:30
Room: Poster & Exhibition Area/Ground Level
Type: Poster Presentation
Tick-borne encephalitis virus in Mongolia
M. Khasnatinov 1 , D. Tserennorov 2 , P. Nymadavaa 3 , E. A. Tchaporgina 4 , T. Glushenkova 4 , E.
Arbatskaya 4 , J. Bataa 3 , D. Abmed 3 , G. A. Danchinova 4 , D. Otgonbaatar 2
1 SC FHHR SD RAMS, Irkutsk, Russian Federation, 2 National Center for Infectious diseases with
natural foci, Ulaanbaatar, Mongolia, 3 National Center for Infectious diseases, Ulaanbaatar,
Mongolia, 4 SC FHHR SD RAMS, Institute of Epidemiology and Microbiology, Irkutsk, Russian
Federation
Background: In Mongolia, Tick-Borne Encephalitis virus (TBEV) now causes approximately 20
cases of disease annually. The disease is registered at national level from 2001 and 75 cases
occurred from 2005 to 2008. We studied main ecological, epidemiological and genetic
characteristics of TBEV in Mongolia
Methods: Questing ticks were collected in forested regions of Northern Mongolia by flagging. The
amount of ticks per 1km was estimated and their species, gender and stage were identified by
morphology. Ticks and human serum samples were analyzed by ELISA, RT-PCR and
sequencing.
Results: The natural foci of TBE are spread in Northern part of Mongolia and linked to the Taiga
Ticks I. persulcatus distribution. The average tick abundance vary from 0,2 tick per km in Huvsgol
aimag to 43 ticks per km in Selenge aimag with the most numerous tick populations in Selenge
and Bulgan aimags. The average TBEV infection rate in ticks in Selenge aimag is 5,5% and in
Bulgan aimag - 4,4%. The rates of TBEV infection for Tuv, Hentii, Orkhon and Huvsgol aimags
are not established so far due to low Taiga tick abundance in these territories. Several popular
objects of pilgrimage, international tourism and recreation were studied to evaluate the risk of
human infection with TBEV and Amarbayasgalant monastery (Selenge aimag) was found to be of
high risk.
The serological survey among 965 residents of Selenge aimag revealed that average 6,2% of
people have the specific antibodies against TBEV.
The genetic characteristics of Mongolian TBEV from ticks and patient indicate that Far Eastern
and Siberian subtypes are common in Mongolia and viral populations are closely related to TBEV
from neighbor regions of Russia – Buryat Republic and Irkutsk Region Conclusion: Thus, the
highest risk of human infection with TBEV in Mongolia is the feature of Selenge and Bulgan
aimags (Fig. 2) and intensive measures of prophylaxis are necessary both for residents and for
tourists in those provinces. This project has been supported by Russian Fund for Basic Research,
grant 08-04-90206-Mong_a.
Figure 2. Prevalence of TBEV in Northern Mongolia and risk of infection for humans