14th ICID - Poster Abstracts - International Society for Infectious ...

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When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 80.006 Session: Pediatric and Perinatal Infections Date: Friday, March 12, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation Epidemiological data of infectious disease for 10 years in PICU F. Zavalani 1 , I. bujari 2 , A. koja 2 , I. bakalli 2 , E. kola 2 , E. Kallfa 2 , S. sallabanda 2 , R. Petrela 2 , R. Lluka 2 , E. celaj 2 1 University hospital center "Mother Theresa", Tirana, AL, Albania, 2 University Hospital Centre "Mother Theresa", Tirana, AL, Albania Background: This is a retrospective study to present the epidemiologic data of the infants hospitalized with infectious diseases in PICU during 1999-2008. Methods: In this study are included 2128 infants from 1 month -14yrs. Admittance criters are based in anamnestic data, clinic situation (valuation of vital signs). The data interpretion is made in report with the kind of infection, with the age, sex, place and mortality. Results: 2128 hospitalized infants with infectious disease in P I C U form 44.39% of all hospitalizations According to the kind of infection, the lower respiratory tract infections take the main place with 1086 cases (51.03 %), infectious diarrhea with 459 cases (21.56%), central nervous system infections with 239 cases (11.23%), septic shock with 89 cases (4.18%), bacterial meningitis with 74 cases (3.47%), upper respiratory tract infections with 66 cases (3.1%), hyperacute sepsis (meningocoxemia) with 47 cases(2.2%), leishmania with 19 cases (0.89%), heart infections (endocarditis, myocarditis, pericarditis) with 12 cases (0.56%), urosepsis with 10 cases (0.46%), skin infections (celulitis, dermatitis) with 10 cases (0.46%), pertussis with 6 cases(0.28 %), varicella with 5 cases (0.23%), tuberculous meningitis with 3 cases (0.14 %),tetanosis with 2 cases (0.093%), salmonella typhi with 1 case (0.046 %). According the age, hospitalized infants are fotmd by: 1 month-1 yrs with 1405 cases (66.02%), 1- 5yrs with 425 cases (19.97%), 5-14 yrs with 298 cases (14.003%). According the sex predominate males with 1198 cases(56.3%) and females with 930 cases(43.7%). According the place, city’s hospitalization (teamwise with suburb) are 1162 cases (54.6%) and from village 966 cases (45.4%). Mortality of infectious diseases is 124 cases (5.827%) where the main place is taken by lower respiratory tract infectious deaths. Conclusion: Infectious diseases take a main place in 1month-1yrs infant morbidity (66.02%).Mortality is with a high percentage of 5.827 %, where the first place is taken by lower respiratory tract infectious diseases with cardiopathia with 87 cases(4.088%).
When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 80.007 Session: Pediatric and Perinatal Infections Date: Friday, March 12, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation The feasibility of rectal artesunate as pre-referral treatment for severe malaria in under fives at community level in rural Uganda J. Rujumba 1 , E. A. Mworozi 1 , B. A. Mpeka 2 , T. Lutalo 2 , R. Azairwe 3 1 Makerere University College of Health Sciences, Kampala, Uganda, 2 Ministry of Health, kampala, Uganda, 3 WHO- Uganda Country Office, kampala, Uganda Background: Malaria is the leading cause of child mortality especially in under five children. It is responsible for 1-2million deaths and 300-500million clinical cases worldwide annually (WHO 2003); 90% of the cases are in sub-Saharan Africa and majority are children under five. Most deaths result from delayed treatment due to various causes. Treatment of severe malaria requires parenteral drugs and skilled personnel yet peripheral health facilities are poorly equipped for this. Timely efficacious treatment at community can “buy” time for patients to reach health facilities. Artemisinin derivatives have been shown to cause rapid reduction of parasite load and resolution of clinical malaria symptoms. We conducted a study to design and evaluate systems for effective community based treatment of severe malaria in under-fives in 2 rural Ugandan districts using rectal Artesunate as pre-referral treatment. Methods: Randomized community trial carried out from 2004-2007. Study phases were formative, development of IEC materials, selection and training of drug distributors, deployment and monitoring of study drug. Results: Acceptability of Rectal Artesunate in treatment of severe malaria in under-five children at community level was high. A total of 1502 children with severe malaria were recruited and referred. A total of 1469/1502 (98%) of treated children recovered, 33(2 %) died mainly due to severe anaemia. Conclusion: Majority (98%) of the treated children with severe malaria recovered. Use of rectal Artesunate at community level reduced mortality due to severe malaria in under-fives and community delivery systems for Rectal Artesunate are feasible and should be scaled-up in rural areas where accessibility to parental and anti malarial therapy is not feasible.
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