14th ICID - Poster Abstracts - International Society for Infectious ...

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When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 84.017 Session: Virology and Viral Infections (Non-HIV) Date: Friday, March 12, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation The study of epidemiological data of varicella and its complications in Albanian children H. Hoxha 1 , E. Kallfa-Foto 1 , G. Lito 1 , R. Petrela 1 , A. Simaku 2 1 University Hospital Center Mother Theresa Tirana, Albania, Tirana, Albania, 2 Institute Public Health, Tirana, Albania Background: Varicella is a serious diseases especially for its complications and even death,may occur in healthy children. Complication have been estimated at a rate of 29.2 per 10000.The serious problem of varicella are reduced after introduced of the vaccine against varicella. The aims of this study was to show epidemiological data ,risk factors and complications of varicella in the Albanian children. Methods: This was a retrospective study and in this study were included 68 children aged 0 to 14 years old admitted in University Hospital Center during January 2004 to December 2008.Epidemiological data analysed were: sex , age,origin,length of hospitalization,risk factors and complications. Results: The mean length of hospitalization was 5.2 days. Age-group most affected was 1-6 years old with 30 cases or 44.12%,followed by children aged 7-14 years old with 22 cases or 32.3%.47 cases or 69.1% were male and there were no difference for origin.We observed this complications : bacterial overinfections: 22 cases or 32.36%(skin and soft tissue infectious caused by S.aureus and S. pyogenes) 4 oteoarthritis,neurological complications : 6 cerebellitis,2 encephalitis,3 status epilepticus, 1 neuritis, 12 varicella pneumonia,1 hepatitis, 1 thrombocytopenic purpura ,1 hemolitic anemia. 18 cases or26.45% under one years old presented enteritis.Acyclovir was used in 26 cases or 38.2%.(mainly complicated). We observed risk factors in 8 cases or (11.8%) as : 3 leucemia ,5 atopic dermatitis. Conclusion: Varicella still remains a frequent infection of childhood ,which often is followed by serious complications. The results of this study can contribute to evaluating the options for varicella vaccination.
When citing these abstracts please use the following reference: Author(s) of abstract. Title of abstract [abstract]. Int J Infect Dis 2010;14S1: Abstract number. Please note that the official publication of the International Journal of Infectious Diseases 2010, Volume 14, Supplement 1 is available electronically on http://www.sciencedirect.com Final Abstract Number: 84.018 Session: Virology and Viral Infections (Non-HIV) Date: Friday, March 12, 2010 Time: 12:30-13:30 Room: Poster & Exhibition Area/Ground Level Type: Poster Presentation Latent manifestations in the US Congenital Rubella Syndrome (CRS) Population N. Armstrong Molloy College, Rockville Centre, ny, USA Background: Since rubella and congenital rubella syndrome (CRS) have not been globally eradicated and populations who do not vaccinate continue to persist, increasing knowledge about adults with CRS remains of great importance. This study investigated the latent CRS manifestations of 174 adults with CRS in the United States, born before 1987 Methods: Cross sectional design. In this study, Helen Keller National Center’s (HKNC) registry was used to identify individuals born with CRS in the United States. Established through an Act of Congress, HKNC is mandated to maintain a national registry of persons who are deaf-blind. The national database, located at HKNC in New York contains personal (race, marital status, residential status, education and employment) and medical (etiology, diagnostic and comorbidities) information on more than 10, 000 deaf-blind individuals with birth dates ranging from 1930-present. According to HKNC, there are approximately 1000 deaf blind individuals 21 and older who are listed as having CRS (HKNC, 2006). According to the CDC, this cohort is the result of the 1963-1965 rubella epidemic. In addition, the registry lists 113 CRS children, ages birth to 21. Results: The survey reported the prevalence of medical disorders including diabetes, cardiac and thyroid dysfunction and glaucoma. Additionally, psychological symptoms such as autistic-like behavior, mood disorder and aggressive behavior were reported Conclusion: CRS is characterized by multiple defects, particularly to the heart, eyes, ears and brain. In utero, the rubella-virus can damage the immune system and vessels which is a harmful starting point for several diseases once the CRS-individual ages. CRS individuals are developing both new medical and psychological symptoms as they age. However, there has been very little information written about this phenomenon, although late onset medical problems have been documented, particularly in the Australian Rubella population born in the 1940s. The results of this study are helpful in understanding both medical and psychological symptoms of the CRS adults, and anticipate potential diseases and behaviors.
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