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CSEM Scientific and Technical Report 2008

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The <strong>CSEM</strong> Electrical Impedance Tomography (EIT) Demonstrator<br />

J. X. Brunner, S. H. Böhm, P. O. Gaggero<br />

EIT has been known for more than 20 years but, in spite of early successes, has not found its way into clinical practice. The main reasons are<br />

cumbersome use <strong>and</strong> the associated poor signal to noise ratio. Both issues are being addressed <strong>and</strong> feasibility is shown in a demonstrator.<br />

Mechanically ventilated intensive care patients with acute lung<br />

failure (75 per 100’000 population) have a mortality rate of 40<br />

to 50%. The lives of many of these patients could be saved by<br />

appropriately adjusting the ventilator if adequate monitoring<br />

were available. Electrical Impedance Tomography (EIT) could<br />

become the key for the dynamic determination of these<br />

optimal settings, as has been shown in first clinical studies [1] .<br />

EIT allows continuous creation of cross-sectional images of<br />

the human body, providing for the monitoring of key body<br />

functions non-invasively <strong>and</strong> without side-effects in real-time.<br />

In contrast to existing technology such as X-ray, CT, MRI or<br />

PET, EIT neither needs ionizing radiation nor bulky <strong>and</strong><br />

expensive equipment. Potentially, an EIT system costs at<br />

least 100 times less than conventional 2D imaging systems.<br />

EIT provides images of body functions such as the local flow<br />

of blood or air rather than just snapshots of body anatomy <strong>and</strong><br />

composition. EIT images can be used in the Intensive Care<br />

Unit (ICU), in emergency medicine <strong>and</strong> at home.<br />

EIT uses 32 electrodes around the chest to inject small<br />

amounts of electrical current <strong>and</strong> to measure the result of<br />

these injections as voltage distributions at the body surface.<br />

The current is very small <strong>and</strong> safe (below 10 mA at around<br />

100 kHz), <strong>and</strong> cannot be felt by the patient. The measured<br />

values are converted into pictures of local conductivities,<br />

which are representative of body tissues <strong>and</strong> fluids, allowing<br />

the real-time monitoring of blood perfusion <strong>and</strong> breathing.<br />

Unfortunately, the EIT electrode assembly is cumbersome <strong>and</strong><br />

difficult to use (Figure 1). <strong>CSEM</strong> is therefore developing an<br />

electrode belt assembly <strong>and</strong> analysis system with the<br />

following components: 32 skin-electrodes with integrated<br />

impedance converters (E-Nodes), chest b<strong>and</strong> with integrated<br />

E-Nodes, data bus around the chest to communicate among<br />

the E-Nodes, a Field Programmable Gate Array FPGA to drive<br />

the E-Nodes <strong>and</strong> demodulate the signals for transfer via<br />

ETHERNET to a connected PC, <strong>and</strong> a PC based image<br />

construction <strong>and</strong> display unit. The E-Nodes apply an AC<br />

current (50 kHz up to 200 kHz), measure voltages in the range<br />

of 0.1 mV to 5 V (absolute <strong>and</strong> relative), provide a program to<br />

switch between current source <strong>and</strong> voltage measurement, <strong>and</strong><br />

apply this program relative to the position around the chest.<br />

The intended use is for intensive care <strong>and</strong> emergency patients<br />

who need mechanical ventilation. Thus, the following<br />

requirements apply:<br />

• Suitable for female & male ICU patients, independent of<br />

body position (supine, prone, upright)<br />

• Permit EIT monitoring for hours up to weeks, will not<br />

impede nursing <strong>and</strong> physiotherapy<br />

• Will not create skin lesions (decubitus), will not restrict<br />

breathing movements<br />

• Applicable in

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