Growth, Differentiation and Sexuality

300 R. Debuchy and B.G. Turgeon
Fig. 15.3. Comparative organization of the MAT locus in
eight Euascomycete species. Analyses are reported for P.
anserina (LG I, supercontig G, 69,500 to 92,000), C. globosum
(LG not determined, supercontig 1.3, bases 3,980,000 to
4,001,000 and supercontig 1.2, bases 4,630,000 to 4,665,000),
N. crassa (LG I, contig 3.86 and 3.87), G. zeae (LG not determined,
contig 1.359 and 1.358), M. grisea (LG III, contig
2.596, 2.597 and 2.600), and E. nidulans (LG VI, contig 1.49
and LG III, contig 1.80). Gene positions are indicated by
arrowed boxes with gene name inside. Below each box is
the gene number, asreferredtobythesequencingproject,
when available. For C. globosum, the number under the box
indicates the percentage of identity at the amino-acid level
with the P. anserina putative homolog. Arrowed boxes with
thick lines indicate C. globosum genes that have no P. anserina
counterparts. Distances and gene sizes are not to scale;
large genome sequences containing genes not relevant to
the comparison have been omitted, and are symbolized by
breaks in the line between genes. The number of genes
present in the break can be inferred from the gene number
adjacent to the break. Gene names refer to the GenBank
name or to a gene encoding a protein showing best similaritytotheputativegeneproductfollowingBlastpanalysis
(Altschul et al. 1997). When no significant similarity was
found, but a conserved domain was found, this domain was
used for identifying the gene. Gene products with no similarity
in Swissprot, nor with any identified domain, are in-
dicatedashypotheticalprotein(hyp. prot.). Aa_trans Transmembrane
amino-acid transporter domain, APC5 similar
to anaphase promoting factor component 5 of S. pombe
(accession no. Q9P4W7), ATG3 similar to autophagocytosis
protein of S. cerevisiae (accession no. P40344), ATPase
cation transport ATPase domain, BGL1 beta glucosidase
homolog (accession number AAB82946.1), cox13 similar to
cytochrome c oxydase polypeptide VIa, mitochondrial precursor,
of S. pombe (accession no. O74471), CWF24 similar
to cell cycle control protein of S. pombe (accession number
Q9P6R8), APN2 similar to DNA (apurinic and apyrimidinic
site) lyase 2 of S. cerevisiae (accession no. P38207),
GAP1 GTPase activating protein homolog (accession no.
AAB82943.1), HMG high-mobility-group domain, endo exo
endo_exo_phos domain, ORF1 similar to S. cerevisiae ORF
YLR456W (accession no. U22383), palI similar to palI of
E. nidulans (accession no. CAA07588), P450 similar to trichodiene
oxygenase of Fusarium sporotrichioides (accession
no. Q12612), PKS similar to conidial yellow pigment
biosynthesis polyketide synthase of E. nidulans (accession
no. Q03149), SLA2 similar to SLA2 transmembrane protein
of S. cerevisae (accession no. P33338), S/T kinase similar to
serine/threonine protein kinase involved in the regulation
of DNA repair in S. pombe (accession no. P40235), SYG1 similar
to SYG1 protein of S. cerevisiae (accession no. P40528),
Tf2p similar to retrotransposable element TF2p 155-kDa
protein type1 of S. pombe (accession no. Q05654)