Growth, Differentiation and Sexuality

Table. 16.1. (continued)
Fruiting Bodies in Ascomycetes 329
Organisms Gene Gene product Defect of mutants Reference
Podospora
anserina
Sordaria
macrospora
Aspergillus
nidulans
wc-2 GATA-like zinc finger No phototropism
Linden and Macino (1997),
transcription factor of perithecial beaks
Oda and Hasunuma (1997)
pp-1 Transcription factor
homeodomain, C2H2 zinc
finger, Ste12p homolog
No protoperithecia Li et al. (2005)
car1 Peroxisomal membrane Impaired karyogamy,
Berteaux-Lecellier et al.
protein
no ascospores
(1995)
cro1 Cytosolic protein
Impaired meiosis,
Berteaux-Lecellier et al.
with C2H2 zinc finger motif no ascospores
(1998)
AS4 Translation-elongation
factor EF-1α, eF1A
No ascospores,
no perithecia
Silar et al. (2001)
su1 Translation-termination Female-sterile,
Gagny and Silar (1998)
factor eRF3
no protoperithecia
su2 Translation-termination Female-sterile,
Gagny and Silar (1998)
factor eRF1
no protoperithecia
PaCox17 Chaperone targeting copper Delayed perithecial formation Stumpferl et al. (2004)
to cytochrome c
and reduced ascus formation
rmp1 No homology, functions Lethal or without mitochondrial Contamine et al. (2004)
in nucleus–mitochondria
cross-talk
targeting sequence, no ascospores
PaNox1 NADPH oxidase No perithecia Malagnac et al. (2004)
PaNox2 NADPH oxidase No ascospore germination Malagnac et al. (2004)
mod-A Proline-rich protein Female-sterile,
Barreau et al. (1998)
with SH3-binding motif no protoperithecia
mod-E Heat-shock protein HSP90 Sterile perithecia, no ascospores Loubradou et al. (1997)
mfp Hydrophobic peptide
pheromone
Male-sterile Coppin et al. (2005)
mfm
mod-D
Peptide pheromone
Gproteinαsubunit Male-sterile
Female-sterile,
no protoperithecia
Coppin et al. (2005)
Loubradou et al. (1999)
PaAsk1 MAPKKK, similar
to S. cerevisiae Bck1p
No perithecia Kicka and Silar (2004)
grisea Copper-activated
Female-sterile,
Osiewacz and
transcription factor, no protoperithecia
Nuber (1996),
ortholog of the yeast
Borghouts and
transcription factor MAC1
Osiewacz (1998)
fle1 Transcription factor, Fewer microconidia, more Coppin (2002)
C2H2 zinc finger
abundant protoperithecia
pah1 Transcription factor, Enhanced number of
Arnaise et al. (2001)
homeobox protein microconidia, delayed
protoperithecia development
ami1 Homolog of A. nidulans Male-sterile, delayed
Graia et al. (2000)
APS-A
fruiting-body formation
pro11 WD-repeat protein No perithecia Pöggeler and Kück (2004)
pro4 Leucine biosynthesis No perithecia Kück (2005)
acl1 Subunit of ATP-citrate-lyase No ascospores Nowrousian et al. (1999)
spo76 Chromosomal protein Impaired meiosis, few ascospores van Heemst et al. (1999)
pro1 C6 zinc finger transcription
factor
No perithecia Masloff et al. (1999)
trpB Tryptophane biosynthesis No cleistothecia Eckert et al. (1999, 2000)
hisB
tubB
Histidine biosynthesis
α-tubulin
No cleistothecia
No ascospores
Busch et al. (2001)
Kirk and Morris (1991)
uvsC DNA-repair enzyme
homolog of S. cerevisiae
RAD51
No karyogamy, no ascospores van Heemst et al. (1997)
lsdA No sequence similarity, No inhibition of cleistothecia Lee et al. (2001)
unknown function development under high salt
conditions