DRS2012 Bangkok Proceedings Vol 4 - Design Research Society

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A Critique of Design Methods in Synthetic Biological Design the definition of these units in its capacity to provide explanations to natural phenomena (Gánti 2007) (Rheinberger 2010). In design, challenging the units of a representation often prove to be more important than the designs themselves as the method of design can drive the products of design towards quite predictable outcomes which can immediately turn into design styles (Stiny 2008, Schumacher, 2010). Biological design not only provides a unique opportunity to rethink the units of the living and expand on how they can be chemically or biologically repurposed for different designs, but also introduces new logics of design that utilize rules and grammars of synthesis, flow, diffusion, and organization that can extend beyond the evolution-bound biological and component-based design paradigms. In today’s engineering, product design, graphic design, architecture, and research, we already witness a bottleneck of creative expression in the design of form and function through unitary methods. As we approach a new frontier in design, where synthetic artifacts will claim more everyday roles, it is becoming increasingly important to set more discursive research agendas that can shape the perception, use, and design of these new artifacts. References Alon, Uri. 2007. An introduction to systems biology: design principles of biological circuits. CRC Press. Antonelli, Paola. States of Design 07: Bio-design - Design - Domus. Domusweb.it. http://www.domusweb.it/en/design/states-of-design-07-bio-design-/. Cogdell, Christina. 2010. Eugenic Design: Streamlining America in the 1930s. University of Pennsylvania Press. Deplazes, Anna, and Markus Huppenbauer. 2009. “Synthetic organisms and living machines : Positioning the products of Synthetic Biology at the borderline between living and non-living matter.” Systems and Synthetic Biology 3 (1-4) (December): 55-63. doi:10.1007/s11693-009-9029-4. Endy, Drew. 2005. “Foundations for engineering biology.” Nature 438 (7067) (November 24): 449-453. doi:10.1038/nature04342. Gánti, Tibor. 2003. The principles of life. Oxford University Press, November 27. Gibson, Daniel G., Gwynedd A. Benders, Cynthia Andrews-Pfannkoch, Evgeniya A. Denisova, Holly Baden- Tillson, Jayshree Zaveri, Timothy B. Stockwell, et al. 2008. “Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome.” Science 319 (5867) (February 29): 1215 -1220. Jacob, François. 1974. The logic of living systems: a history of heredity. Allen Lane. Krohs, Ulrich, and Peter Kroes. 2009. Functions in biological and artificial worlds: comparative philosophical perspectives. MIT Press, March 31. Luisi, Pier Luigi, and Cristiano Chiarabelli. 2011. Chemical Synthetic Biology. John Wiley & Sons, May 31. Mead, Carver, and Lynn Conway. 1979. Introduction to VLSI Systems. Addison-Wesley Pub (Sd), December. Pearson, Helen. 2006. “Genetics: What is a gene?” Nature 441 (7092) (May 25): 398-401. doi:10.1038/441398a. Purnick, Priscilla E. M., and Ron Weiss. 2009. “The second wave of Synthetic Biology: from modules to systems.” Nat Rev Mol Cell Biol 10 (6) (June): 410-422. doi:10.1038/nrm2698. Rasmussen, Steen. 2009. Protocells: bridging nonliving and living matter. MIT Press. Rheinberger, Hans-Jörg. 1997. Toward a history of epistemic things: synthesizing proteins in the test tube. Stanford University Press. Rheinberger, Hans-Jorg, and Hans-Jörg Rheinberger. 2010. An Epistemology of the Concrete: Twentieth- Century Histories of Life. Duke University Press Books, September 6. Sia, Samuel K., et al. "An Integrated Approach to a Portable and Low-Cost Immunoassay for Resource-Poor Settings." Angewandte Chemie International Edition. 2004. Conference Proceedings 1851
1852 Conference Proceedings Orkan TELHAN Schumacher, Patrik S. 2011. The Autopoiesis of Architecture: A New Framework for Architecture. 1st ed. Wiley, January 18. Stiny, George. 2008. Shape: Talking about Seeing and Doing. The MIT Press, January 25. Szallasi, Zoltan, Jörg Stelling, and Vipul Periwal. 2010. System Modeling in Cellular Biology: From Concepts to Nuts and Bolts. The MIT Press, March 31. Wagler P.F., U. Tangen, T. Maeke, H.P. Mathis, J.S. McCaskill Smart Materials and Structures 2003, 12(5), 757-762.
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