Dédicaces - Faculté de Médecine et de Pharmacie de Fès

SUMMARY
The laryngeal cancer is a common tumor in men, but still rare among women.
Our work is a retrospective study from January 2003 to December 2007, it involves
11 cases of larynx cancer in women followed in our department of ENT at the
hospital OMAR DRISSI of Fez.
The mean age of our patients was 51 years, review of past medical historypointed
out 3cases of important passive smoking with an average of 10 packs-years, no
case of active smoking had been noted. The notion of exposure to smoke from
burning wood is found in 5 patients, all our patients are of rural origin.
The average duration between the onset of clinical signs and consultation was 9
months. Dysphonia was the revealing clinical sign in 9 patients over 11, it’ is often
associated with the evolution course of dyspnea. Dysphagia as telling sign is found
in only two cases. All patients have benefited from endoscopy with biopsy, which
confirmed the diagnosis of epidermoid carcinoma in most cases (10/11). Imagery
allowed us to assess the extension, wich pointed out an advanced stages in most
cases (Stade4 (a): 6 patients ).
The treatment consisted of a radio-surgical combination in 7 cases, surgery alone in
one case, an exclusive radiotherapy in two cases, and an association
radiochemothérapy in one case.
The course was marked by a carcinological loco-regional control in 6 cases, one
patient presented a tumor recurrence and two patients were lost of sight. We
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