(19) 대한민국특허청(KR) (12) 공개특허공보(A) - Questel

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도면46 서 열 목 록 Smith, Jeffrey T.L. Schatzman, Randall C. Litton, Mark J. Latham, John SEQUENCE LISTING ANTAGONISTS OF IL-6 TO PREVENT OR TREAT CACHEXIA, WEAKNESS, FATIGUE, AND/OR FEVER 67858.707002 PCT/US2009/006273 - 254 - 공개특허 10-2011-0091780
2009-11-24 61/117,861 2008-11-25 61/117,839 2008-11-25 61/117,811 2008-11-25 12/502,581 2009-07-14 12/399,156 2009-03-06 12/391,717 2009-02-24 12/366,567 2009-02-05 728 PatentIn version 3.5 1 183 PRT Homo sapiens 1 Val Pro Pro Gly Glu Asp Ser Lys Asp Val Ala Ala Pro His Arg Gln 1 5 10 15 Pro Leu Thr Ser Ser Glu Arg Ile Asp Lys Gln Ile Arg Tyr Ile Leu 20 25 30 Asp Gly Ile Ser Ala Leu Arg Lys Glu Thr Cys Asn Lys Ser Asn Met 35 40 45 Cys Glu Ser Ser Lys Glu Ala Leu Ala Glu Asn Asn Leu Asn Leu Pro 50 55 60 Lys Met Ala Glu Lys Asp Gly Cys Phe Gln Ser Gly Phe Asn Glu Glu 65 70 75 80 Thr Cys Leu Val Lys Ile Ile Thr Gly Leu Leu Glu Phe Glu Val Tyr - 255 - 공개특허 10-2011-0091780
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(51) Int. Cl. (19) 대한민국특
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특허청구의 범위 청구항 1
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것을 특징으로 하는 방법.
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공개특허 10-2011-0091780 속질
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청구항 35 청구항 1에 있어
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으로 하는 방법. 청구항 55
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[0003] [0004] [0005] [0006] [0007]
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[0019] [0020] [0021] [0022] [0023]
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[0029] [0030] [0031] [0032] [0033]
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[0042] [0043] [0044] [0045] [0046]
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[0059] [0060] [0061] [0062] [0063]
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[0080] [0081] [0082] [0083] [0084]
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[0110] [0111] [0112] [0113] [0114]
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[0125] [0126] [0127] [0128] [0129]
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[0143] [0144] [0145] [0146] [0147]
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[0156] [0157] [0158] [0159] [0160]
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[0168] [0169] [0170] [0171] [0172]
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[0192] [0193] [0194] [0195] [0196]
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[0218] [0219] [0220] [0221] [0222]
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[0246] [0247] [0248] [0249] [0250]
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[0270] [0271] [0272] [0273] [0274]
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[0296] [0297] [0298] [0299] [0300]
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[0324] [0325] [0326] [0327] [0328]
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[0349] [0350] [0351] [0352] [0353]
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[0375] [0376] [0377] [0378] [0379]
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[0402] [0403] [0404] [0405] [0406]
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[0428] [0429] [0430] [0431] [0432]
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[0455] [0456] [0457] [0458] [0459]
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[0480] [0481] [0482] [0483] [0484]
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[0505] [0506] [0507] [0508] [0509]
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[0533] [0534] [0535] [0536] [0537]
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[0558] [0559] [0560] [0561] [0562]
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[0578] [0579] [0580] [0581] [0582]
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[0623] [0624] [0625] [0626] [0627]
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[0675] [0676] [0677] [0678] [0679]
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[0707] 표 1 - 71 - 공개특허 10
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[0709] [0710] [0711] [0712] [0713]
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[0723] [0724] [0725] [0726] [0727]
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[0738] [0739] [0740] [0741] [0742]
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[0752] [0753] [0754] [0755] [0756]
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[0772] [0773] [0774] [0775] [0776]
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[0793] [0794] [0795] [0796] [0797]
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[0815] [0816] [0817] [0818] [0819]
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[0836] [0837] [0838] [0839] [0840]
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[0858] [0859] [0860] [0861] [0862]
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[0881] [0882] [0883] [0884] [0885]
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[0903] [0904] [0905] [0906] [0907]
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[0926] [0927] [0928] [0929] [0930]
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[0948] [0949] [0950] [0951] [0952]
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[0969] [0970] [0971] [0972] [0973]
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[0992] [0993] [0994] [0995] [0996]
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[1014] [1015] [1016] [1017] [1018]
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[1023] [1024] 을 지칭한다. 이
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[1032] [1033] [1034] [1035] [1036]
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[1052] [1053] [1054] [1055] [1056]
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[1074] [1075] [1076] [1077] [1078]
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[1112] [1113] [1114] [1115] [1116]
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[1146] [1147] [1148] [1149] [1150]
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[1163] [1164] [1165] [1166] [1167]
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[1179] [1180] [1181] [1182] [1183]
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[1197] [1198] trained male runners,
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[1199] [1200] 8; Lange, A., et al,
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[1201] interleukin-6 monoclonal ant
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[1202] [1203] [1204] [1205] [1206]
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[1210] [1211] [1212] [1213] [1214]
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의 웰(well) 중에서 9개가 항
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[1238] [1239] [1240] [1241] [1242]
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[1255] [1256] [1257] [1258] [1259]
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[1491] [1492] [1493] [1494] [1495]
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[1849] [1850] [1851] [1852] [1853]
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[1910] [1911] [1912] [1913] [1914]
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[1971] [1972] [1973] [1974] [1975]
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[2031] [2032] [2033] [2034] [2035]
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[2275] [2276] [2277] [2278] [2279]
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[2335] [2336] [2337] [2338] [2339]
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[2395] [2396] [2397] [2398] [2399]
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[2637] [2638] [2639] [2640] [2641]
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도면 도면1 - 201 - 공개특허
Page 203 and 204: 도면3 - 203 - 공개특허 10-201
Page 205 and 206: 도면5 - 205 - 공개특허 10-201
Page 207 and 208: 도면7 - 207 - 공개특허 10-201
Page 209 and 210: 도면9 - 209 - 공개특허 10-201
Page 211 and 212: 도면10b - 211 - 공개특허 10-2
Page 213 and 214: 도면10d - 213 - 공개특허 10-2
Page 215 and 216: 도면11 - 215 - 공개특허 10-20
Page 217 and 218: 도면13 - 217 - 공개특허 10-20
Page 219 and 220: 도면15 - 219 - 공개특허 10-20
Page 221 and 222: 도면17 - 221 - 공개특허 10-20
Page 223 and 224: 도면19 - 223 - 공개특허 10-20
Page 225 and 226: 도면21 - 225 - 공개특허 10-20
Page 227 and 228: 도면23 - 227 - 공개특허 10-20
Page 229 and 230: 도면25 - 229 - 공개특허 10-20
Page 231 and 232: 도면26b - 231 - 공개특허 10-2
Page 233 and 234: 도면28 - 233 - 공개특허 10-20
Page 235 and 236: 도면30 - 235 - 공개특허 10-20
Page 237 and 238: 도면32 - 237 - 공개특허 10-20
Page 239 and 240: 도면34a - 239 - 공개특허 10-2
Page 241 and 242: 도면35a - 241 - 공개특허 10-2
Page 243 and 244: 도면36a - 243 - 공개특허 10-2
Page 245 and 246: 도면37a - 245 - 공개특허 10-2
Page 247 and 248: 도면38 도면39 - 247 - 공개특
Page 249 and 250: 도면41 - 249 - 공개특허 10-20
Page 251 and 252: 도면43 - 251 - 공개특허 10-20
Page 253: 도면45 - 253 - 공개특허 10-20
Page 257 and 258: 100 105 110 Gly Tyr Ser Leu Arg Asn
Page 259 and 260: PRT Oryctolagus cuniculus 8 Ile I
Page 261 and 262: 48 DNA Oryctolagus cuniculus 16
Page 263 and 264: Asp Phe Ala Thr Tyr Tyr Cys Gln Gln
Page 265 and 266: 1 5 10 24 7 PRT Oryctolagus cun
Page 267 and 268: DNA Oryctolagus cuniculus 31 cagg
Page 269 and 270: 38 Met Glu Thr Gly Leu Arg Trp Leu
Page 271 and 272: 45 496 DNA Oryctolagus cuniculus
Page 273 and 274: PRT Oryctolagus cuniculus 53 Met
Page 275 and 276: Gly Ala Ser Thr Leu Asp Ser 1 5 57
Page 277 and 278: 21 DNA Oryctolagus cuniculus 64
Page 279 and 280: Gly Thr Pro Leu Thr Leu Thr Cys Thr
Page 281 and 282: acatttgccc aagtgctgac ccagactcca tc
Page 283 and 284: Leu Pro Gly Ala Thr Phe Ala Ala Val
Page 285 and 286: 89 Leu Gly Gly Tyr Asp Asp Asp Ala
Page 287 and 288: caggcatcca aactggcatc t 21 97 33
Page 289 and 290: Trp Ile Gly Met Ile Tyr Gly Ser Asp
Page 291 and 292: tcatcgcggt tcaaaggcag tggatctggg ac
Page 293 and 294: Gly Met Ile Tyr Gly Ser Asp Glu Thr
Page 295 and 296: 122 Met Asp Thr Arg Ala Pro Thr Gln
Page 297 and 298: 1 5 128 16 PRT Oryctolagus cuni
Page 299 and 300: Oryctolagus cuniculus 136 tacatttg
Page 301 and 302: 1 5 142 11 PRT Oryctolagus cuni
Page 303 and 304: 150 33 DNA Oryctolagus cuniculus
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Arg Gly Gly Tyr Ala Ser Gly Gly Tyr
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aaggggctgg agtggatcgg atacatttgg ag
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Met Glu Thr Gly Leu Arg Trp Leu Leu
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gtcaccatca attgccagtc cagtcagagt gt
Page 313 and 314:
50 55 60 Pro Pro Lys Leu Leu Ile Ty
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Gly 193 11 PRT Oryctolagus cuni
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201 gggatttatt ctgataataa ttattatgc
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1 5 207 6 PRT Oryctolagus cunic
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18 DNA Oryctolagus cuniculus 215
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220 Gln Ala Ser Gln Ser Val Ser Ser
Page 325 and 326:
DNA Oryctolagus cuniculus 228 cag
Page 327 and 328:
35 40 45 Ser Tyr Trp Met Cys Trp Va
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ggtgattgtt atgct 375 243 357 DNA
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Leu Thr Ile Thr Asp Val Gln Cys Asp
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1 5 10 258 369 DNA Oryctolagus
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Met Asp Thr Arg Ala Pro Thr Gln Leu
Page 337 and 338:
1 5 272 16 PRT Oryctolagus cuni
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DNA Oryctolagus cuniculus 280 gtc
Page 341 and 342:
Leu Ala Ser Thr Leu Ala Ser 1 5 28
Page 343 and 344:
ctggcatcta ctctggcatc t 21 294 30
Page 345 and 346:
Arg Thr Ser Asp Ile Phe Tyr Tyr Arg
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ccgacaaccg aggacacggc cacctatttc tg
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Val Gln Cys Gln Ser Val Glu Glu Ser
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gtcaccatca actgccagtc cagtcagagt gt
Page 353 and 354:
50 55 60 Pro Pro Lys Leu Leu Ile Ty
Page 355 and 356:
Ile Ile Ser Ser Ser Gly Ser Thr Tyr
Page 357 and 358:
Oryctolagus cuniculus 345 gggggtgc
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Oryctolagus cuniculus 350 Gln Gln
Page 361 and 362:
358 caacagggtt atagtagtag ttatgttga
Page 363 and 364:
13 PRT Oryctolagus cuniculus 364
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caaatgacca gtctgacagc cgcggacacg gc
Page 367 and 368:
Val Gln Cys Gln Ser Leu Glu Glu Ser
Page 369 and 370:
gtcaccatca agtgccaggc cagtcagagc at
Page 371 and 372:
Gly Gln Pro Pro Lys Leu Leu Ile Tyr
Page 373 and 374:
1 5 10 15 Gly 401 14 PRT Orycto
Page 375 and 376:
DNA Oryctolagus cuniculus 409 gaa
Page 377 and 378:
Gln Cys Thr Tyr Gly Thr Ile Ser Ile
Page 379 and 380:
423 15 DNA Oryctolagus cuniculus
Page 381 and 382:
Gln Ala Ser Glu Asp Ile Glu Ser Tyr
Page 383 and 384:
caggccagtg aggacattga aagctatcta gc
Page 385 and 386:
Trp Ile Gly Phe Ile Asn Thr Gly Gly
Page 387 and 388:
451 atggagactg ggctgcgctg gcttctcct
Page 389 and 390:
459 126 PRT Oryctolagus cuniculu
Page 391 and 392:
Oryctolagus cuniculus 466 atggacac
Page 393 and 394:
20 25 30 Val Ser Ala Ala Val Gly Gl
Page 395 and 396:
Oryctolagus cuniculus 480 Ile Ile
Page 397 and 398:
Page 399 and 400:
Oryctolagus cuniculus 494 Gln Gln
Page 401 and 402:
502 caacagggtg ctactgtgta tgatattga
Page 403 and 404:
Oryctolagus cuniculus 508 Gln Ala
Page 405 and 406:
Oryctolagus cuniculus 516 caggccag
Page 407 and 408:
Asn Tyr Tyr Ile Gln Trp Val Arg Gln
Page 409 and 410:
DNA Oryctolagus cuniculus 531 atg
Page 411 and 412:
Gln Gly Tyr Tyr Ser Gly Val Ile Asn
Page 413 and 414:
366 DNA Oryctolagus cuniculus 54
Page 415 and 416:
1 5 10 15 Leu Pro Gly Ala Arg Cys A
Page 417 and 418:
17 PRT Oryctolagus cuniculus 560
Page 419 and 420:
DNA Oryctolagus cuniculus 568 tac
Page 421 and 422:
Ser Ala Ser Thr Leu Ala Ser 1 5 57
Page 423 and 424:
Page 425 and 426:
20 25 30 Phe Pro Glu Pro Val Thr Va
Page 427 and 428:
590 15 PRT Homo sapiens 590 Val
Page 429 and 430:
599 Ile Arg Tyr Ile Leu Asp Gly Ile
Page 431 and 432:
609 15 PRT Homo sapiens 609 Glu
Page 433 and 434:
Homo sapiens 618 Lys Ile Ile Thr G
Page 435 and 436:
1 5 10 15 628 15 PRT Homo sapie
Page 437 and 438:
PRT Homo sapiens 637 Thr Asn Ala
Page 439 and 440:
1 5 10 15 647 111 PRT Oryctolag
Page 441 and 442:
35 40 45 Tyr Lys Ala Ser Ser Leu Gl
Page 443 and 444:
Arg 654 97 PRT Homo sapiens 65
Page 445 and 446:
120 PRT Artificial sequence Huma
Page 447 and 448:
Val Ser Ala Ala Val Gly Gly Thr Val
Page 449 and 450:
Ser Leu Arg Leu Ser Cys Ala Ala Ser
Page 451 and 452:
Ser Leu Arg Leu Ser Cys Ala Ala Ser
Page 453 and 454:
Arg Val Thr Ile Thr Cys Gln Ala Ser
Page 455 and 456:
85 90 95 Leu Lys Met Thr Ser Leu Th
Page 457 and 458:
65 70 75 80 Ala Lys Gly Arg Phe Thr
Page 459 and 460:
50 55 60 Glu Trp Ile Gly Phe Ile Th
Page 461 and 462:
35 40 45 Ser Tyr Ala Met Ser Trp Va
Page 463 and 464:
20 25 30 Gly Thr Pro Leu Thr Leu Th
Page 465 and 466:
Met Glu Thr Gly Leu Arg Trp Leu Leu
Page 467 and 468:
Leu Gly Cys Leu Val Lys Asp Tyr Phe
Page 469 and 470:
Leu Gly Cys Leu Val Lys Asp Tyr Phe
Page 471 and 472:
Arg Glu Ala Lys Val Gln Trp Lys Val
Page 473 and 474:
700 360 DNA Oryctolagus cuniculu
Page 475 and 476:
Oryctolagus cuniculus 703 gaggtgca
Page 477 and 478:
Ser Arg Thr Pro Glu Val Thr Cys Val
Page 479 and 480:
115 120 125 Arg Thr Val Ala Ala Pro
Page 481 and 482:
100 105 110 Cys Ala Arg Asp Asp Ser
Page 483 and 484:
Asp Asp Phe Ala Thr Tyr Tyr Cys Gln
Page 485 and 486:
Gly 719 330 PRT Artificial Sequ
Page 487 and 488:
721 gcctatgata tgacccagac tccagcctc
Page 489 and 490:
20 25 30 Ser Asp Thr Ser Tyr Val Se
Page 491 and 492:
Tyr Arg Ala Glu Arg Ser Lys Thr Phe
Page 493 and 494:
225 230 235 240 Lys Leu Thr Trp Thr
Page 495:
725 730 735 Ser Arg Pro Ser Ile Ser
show all

(19) 대한민국특허청(KR) (12) 공개특허공보(A) - Questel

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