Fulltext - SBU

Table 3.4.1 Effects of prophylaxis with otic drops on otorrhea.AuthorYearReferenceCountryStudydesignPopulationInterventionControlGiles et al2007[140]USARCTSingleblindn=207Age: 4.5 months–4 years72% 1 year or less with OM85% 2 years or less withOMrAOM 61%SOM 29.5%Ciprodex (ciprofloxacin0.3%+dexamethasone0.1%) 4 drops x 2 for5 days: n=103 (198 ears)No treatment: n=104(200 ears)Poetker et al2006[121]USARCTrandomisedbetween earsSingleblindn=306Age: 5–146 months(mean 22.7 months)SOM or rAOMFLOX (ofloxacin oticdrops): n=99COS (neomycin-sulfate +polymyxin B otic drops):n=91No treatment: n=873 days (if dry middle ear)10 days if SOMKocaturk et al2005[126]TurkeyRCTSingleblindn=280Age: mean 5.8 years(3–9 years)SOM >8 weeksrAOM >6 in 6 monthsNaCl irrigation before VT:n=70Oral ampicillin for 5 days:n=70Ofloxacin ear drops for5 days: n=70Hearing loss and noinfections at surgeryNo treatment: n=70150Rörbehandling vid inflammation i mellanörat