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Table 3.1.1 Effect of ventilation tubes for preventionof recurrent acute otitis media (rAOM)AuthorYearReferenceCountryStudy designPatientpopulationInterventionControlCasselbrant et al1992[56]USARCTDouble-blindaccording tomedicationn=264Age: 7–35 monthsInclusion criterium:≥3 AOM in 6 months≥4 AOM in 12 monthsNo effusion at entryNo adenoidectomyAmoxicillin x 1: n=90Placebo for amoxicillin:n=88VT: n=86Le et al1991[54]USARCTRandomisationbetween earsn=44Age: 9–82 months(mean 20.4 months)Inclusion criterium:rAOM bilaterally>6 episodes/year or>4 episodes for childrenyounger than 1 yearVT: 44 earsMyringotomy: 22 earsControl: 22 earsAll had antibiotics 3months before surgeryGebhart1981[55]USARCT n=108Age: 6–36 monthsInclusion criterium:>3 AOM in 6 months56% also had SOMVT: n=58No VT: n=50AOM= Acute otitis media; ns = Not significant; RCT = Randomised controlled trial;SOM = Secretory otitis media; rAOM = Recurrent acute otitis media; VT = Ventilation tube86Rörbehandling vid inflammation i mellanörat