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Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...

Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...

Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...

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.pfstd ttdiei3 ol c.tizitu dd z'todiDi4<br />

pHl<br />

0j9r<br />

o-9956<br />

'fte 6ult5 (la!I. 3.83) <strong>of</strong> anlodip<strong>in</strong>q showed rhlr no <strong>in</strong>teredon dt oy pH lclels. The rry<br />

sF.iropnobtErcric valus <strong>of</strong> eririzjE rnd dlodipirc ar all pH l*ls @8ed b.rven 90l0l%<br />

md 95- 109%. rspecti!.ly md on HPLC rtuged belw@n 9t- l Ot "/o for bolh th€ dru8s.<br />

r.b|. 313<br />

In@E iM /6ulB oJdirizke vith an!.dip<strong>in</strong> on UV tpzcnoplotmtry dd<br />

EPLC<br />

PH9<br />

HDLC HPLC HPT' HPLC<br />

97.24 99.82, 98.45 91.20 98.82<br />

I5 91.20 9.25<br />

l0 98,15 t00.5) I00.3t 96.J4 t00 7l 93_62<br />

100 8.1 t00.?.1 93.19 r00.90<br />

94.42 t00.41<br />

98.48 93.33 93,51<br />

90 99.07 99.52 101.65 98.71 100.41 97.84<br />

95.16 t00.3t 9l.ill<br />

99.42 93.55 l0t.5l<br />

99.1| r00.31<br />

I5 99.11 93.t5 9n 89 t00.42 rol &<br />

t0 95.0E r00.9t 96.2t 9,78 r0o,7l<br />

99.20 96.54 97.49 93.92 t01.4 |<br />

97_t8 100.61 93_3J<br />

91.51 99.43<br />

99.85 94.71 100.08 100.89 99.85<br />

105 l{x)91 100.62 t0t.65 98,72 100.26 97.O1<br />

Cdniri!. ri.n NSAID'!<br />

98.54 100.37 96.88 100.86<br />

S<strong>in</strong>uhdtuow zleterkituioa <strong>of</strong>@tirlzltu ihyeMA@ <strong>of</strong>NSA|DS b, Rp- H.LC<br />

96

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