Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...

fY*.
iO
h
s I
...6., !t f,t
rvii rot-rcrYn nm
.4, U z.c c,4/ V c'*y' \t
r^ria .s\ tlL (fi
t
lr'^u,
14ris
,IrI!
roalff
2'C
tl
.
PtlotlIo'Ff
9
r-tr
I
0
tl
"_"oT
t8t{ , {ior
a.^fl
r'l
6 MdLe {art
i Spcnoscopic mthods
IE ain€rioni€ &tihi!Lnine cctirizine sd ib p@nt &[g hyd&xyzin a c&&M
@nF ad lw @i..d fd U.i! 3D rrirres rrd dr|mie. th. rm b6sic pK! ldues,
lhc mosl @@or @rfomlrioc for .a.h clatF! sFci* \Nft dlit milcd by molaul{
dlMica sinulationr &d €onnmd by NMR h6l!4cnG. Fo @tirizine, lh. re$lls
d.noBhr.d that tlE eitt ri6 qhicb v@ rh. pr.donimr spe.a6 d r,bsiologic.l pH
.xilred a foldcd @nfomlts, wh@a irl nomqtiouc sFcic! dtpl.y.d folded @nfom6
to