Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...

For cctirizin€ th€ o/dv.jlability ieged berwan 120.96182.11 % sd I15.62-191.?3 % by
UV spebophotoneter ed H?LC Esp€ctiv.ly, Thc % avanatiliq ofmcbn@ ir pr.se
of ccti.irift dsased 10 c aignif@t qr.!! N.ihlilirt of c.ririAft @ 2_06{6.2e W
lJv-vi3ible stFtophoromacry and 42.6t68.49.a bJ HILC.
I.bl.3J05
tr4 t9
HPI' HPt,c
t0o.t2 91_Zl .r9.39
I5 91tl t2_6 88.15 36.71 6l.tl aJ6
30 57.11 l5 34 39. t9
27.47 56.23
19i 35.49 102.5 65.67
2.11 33.11 64.67 78 88
2.25 63.9t 7t.tt
105 63.It
r20
100 10008 96,59
l5 2.9 I10.99 l0l24 110.25 1t2.55
30 t30.16 79.33 103.07 |]0.62 ll6.2l
t2t.t1 tu.32 105.13 I6t.5?
\t2.17 l.l4.tJ t24.t6 I09.21 l1t_62
7t 113.6 ltt.78 115.84 t06.41 141.3
I14,06 r40.88 t26.62 1t0.87
r05 I17.63 178 6 112.88 143.9 149.32
t20 t20 96 I9l.7l t2t.75 ll5 62 l82.rt
Inl @lion nudi6 s@ fsnhd supponed by th.modynmic d!t!. lt ws obsd.d ftom
themodyMi€ dal, thai sponhrcous qcrio. have ocared be$e€n NSAIDS ad etirizine,
6 dl itr. Cibbs Ge o65, vdu6 \'@ fo6d 10 b€ rcg.tivc.In s simild ey, helI 6nLnr
vdB *w .lso fould to b. eg.tiv., *I|icn shoved rh.r @hdd fotuio! is duc b
cb.l.li@. En$oDy val6 for all de ini.*ti@s *w fourd ro b. positiw qc.pr for
b.loxicM in pH 4 at all thrc. r€mFEtc. N.gaiive €ntopy v.luca of meloxi.m indic.red
doror eepbr mnpl€x forrutio. due lo hydrcgc. bondiq dd ch.larion.
107