Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...
Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...
Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...
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nutritiomlfrctos dd Fvenl dist* sl!l$ h6 now be@ !@cniz!d. Z<strong>in</strong>c is rcquiFd for<br />
ndy biologicsl turctioN imlnd<strong>in</strong>g DNA synthcais, kll divisiotr ed gde dpcssion. ll is<br />
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z<strong>in</strong>c is nad.d for @ll-n dial€d ilmuity. U601, d.ily EquiEne is l0lo l5 h& l0lo40<br />
% <strong>of</strong> the di.lary z<strong>in</strong>c is abe.bed ftom lhc arDll i.Gsti@, the absQtion appea to be<br />
Mi.r.d wirh nuiilionrl $ars [16l]. Absolprion <strong>of</strong> ntr ba b@ d€cEa.d wilh rhe<br />
fomalioD <strong>of</strong> <strong>in</strong>soluble mmpldB wilh phrlli. (@rcrlt, calciu, villln<strong>in</strong> D, prctc<strong>in</strong> dd<br />
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kidrcys h.v€ liul€ or no rcle <strong>in</strong> rcsulat<strong>in</strong>s the cont nt <strong>of</strong>zi@ <strong>in</strong> lhe body 0631.<br />
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eulc ed chrcnic clfdrs od halll dd dvimmo. CadniM is .ol d€gmdabl. <strong>in</strong> tutft<br />
dd will ths, on@ lelq$d lo rhe envirmen|, stay <strong>in</strong> cionstion. Nw elcss add lo $e<br />
alaady .xist<strong>in</strong>e d.posis <strong>of</strong> @dsim <strong>in</strong> rhc e.vircm.ni. Csdmim tud codniu conpobds<br />
m, @np@d !o other h€avy b.lals, relatilely MLr sluble. They N th€Efore also noE<br />
Dobile <strong>in</strong> €.s. soil, senerolly more bioavailabl. &d t€nd lo bi@mulat€. Chonic @dnim<br />
exposw produc.s a wi.l€ vdiely <strong>of</strong> &u. &d ctronic €fsrs <strong>in</strong> hdm. cadniw<br />
umulat.s <strong>in</strong> tlE humm body dd €sFcially <strong>in</strong> rhc tidn ts [164]. Cadrbim sulphid. ed<br />
cidniM sdd.tc had betr used for rh€ r,lsl,ndt <strong>of</strong> st<strong>in</strong> @ndition &d cy. iritclion,<br />
Gpetilcly 1165l A suficior @@E tid (200 l1r/s) dabasd ilE Lidney cell, Gultiry <strong>in</strong><br />
preximal ruhle i.juty and Fote<strong>in</strong>uia U66l- ln rh. GI te! rhe abGotplon <strong>of</strong> cldniE is<br />
poo', studies <strong>in</strong> $e laboFtory e<strong>in</strong>als <strong>in</strong>diqLd tht enenr <strong>of</strong> absorydon lo b€ only l.t%<br />
[167] md limit d sludies <strong>in</strong> M <strong>in</strong>dlcated d valu. <strong>of</strong> 6bout 5%. Appoximolely 50vo <strong>of</strong>$e<br />
toral body bu.den, aner dhtdbution is foud <strong>in</strong> lhe liver dd kidneys. Livei dd kidney<br />
cont <strong>in</strong>s n.tallolhion€n, which is <strong>in</strong>d@ible by .xposw $ cadsiM [68].<br />
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