Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...
Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...
Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...
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Irr &nltri.al nsim for feotidirc .t stomh pH i,c. I sd 4 w fou[d 10 b.266 m<br />
vh.@, .t blood ad <strong>in</strong>t4t<strong>in</strong>li pH it wB !r 284 m. S<strong>in</strong>c. th. spccr! <strong>of</strong> f.sotidirc did nor<br />
<strong>in</strong>tcrfdc wilh thc ru<strong>in</strong>. <strong>of</strong> cdnizirc<br />
h@e 3imllllEoa cqulrion w6<br />
.p!li.d to qutit t thc rrc dru$ <strong>in</strong><br />
th. mixtuF. Th. .pilotr vdB lr@<br />
€lcol.t d a pBdt d <strong>in</strong> rh. rdL<br />
1.36,<br />
pHl t6t0o QN 761.6<br />
l3t0() 3I4I 625.51<br />
16350 755t.91 1718 l|lt.56<br />
pH9 l6rr0 7157_99 5565 186.59<br />
T.!h ljt<br />
na I W q*bopletoNtr dd EPLC<br />
tl PH<br />
HPLC HPI.C HPt' HPLC<br />
9E,n 10t.9 t00,2 99,,1t l0t.? tm.7 tott<br />
It 96_51 9.52 91.52 t0t,7 t01,3 9E.54 91.5,t<br />
JO t02.0 9t.05 t00,6 98,J' t00.4<br />
Ll n.25 10t.3 91.12 9.tl 98_n to2t<br />
r@.6 9,23 98.31 9n7 9t.75<br />
15 t00.5 t00.2 I0t.9 93.t9 99.t! 98A2<br />
90 9.28 l0t.l 94,61 t00,3 9t,57 100.3 99.55<br />
t05 r(x).8 100.4 r0t.l ,9E3 9E,t2 100.7 I00.3<br />
r20 t00.! t0t,4 roo.5 (x).O 9.0t t00.7 91.25<br />
0 9,,52 100.7 tot.9 .12<br />
It 94.67 100,8 9tt 9t.09 t0t,6 9t.6t t00.6<br />
30 9,12 l0o,l 9t.u, t00,8 9t.12 t00.8<br />
99.24 9.12 91.4! 99.65 l0!.t<br />
6o t00,6 98.?l 100.., 9.t0 99t8<br />
97,00 9t.l! 98.,16 rm_8 I00.7 !00.1 99,2t 99l0<br />
98.2t 100.2 t00.8 t0t-7 tt.52 t00.7<br />
105 l03J t00.5 t0o,? t00.t roo_t<br />
t2o 100.1 I00.3 100,3 tl.il5 99,71 I(x}JI t0t_8<br />
Ihe <strong>in</strong> dcti6 sfu(|i$ p.rfodiFd on W spoctup[otomcrry .nd HPLC (r!bt. 3.]r) ddty<br />
irdiorcddr.tceri.iz<strong>in</strong> w!v.il.bt.upio97-104%<strong>in</strong>.Id!.buflcrn di@.Inrh.e.<br />
hy t[. wailalility <strong>of</strong> fo&otidir. E fould io h. 96- 103% by ul<strong>in</strong>g borb rb. t chdqrcs.<br />
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