Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...

3 Notst@idd .ttiJnfunmto,f dr.tt (NSAIDt)
Irre uLdo8enic popenies ofNSAIDs sr€h fto6 the fact rhat they ft orBei. &id!, which
@ initat. rhe gsEic nu@e and ale non th€n inhibiiory .frec& on prosLglddir
biosyntlElb. NSAIDS h8. ben @mi.lly tsilable lior decad.s ed e wll ttum to
Ed@ pah lDd innMado! [rr] cbD.ic us.s. of rh* drugs h|! b@ assidcd wnt
lhe poFnlity for sid€ .fi€cts such N gsboint$tiral idilalion ed slppE$ion of Enal
fiNlion in prn of the popularioi U 12- 1141.
Ns,lIDs 3.t.tuI Jq i"!@jN Ot11l
5-benayLa-sedtyl 2rhioDh.n.rc.lic &id. CxHuOls
of 260.3 & whit micrccryslrllii., insoluble in
we, n6ly eluble b don., .lohol rd
2{2,6iic!lr!pt ryl) ditul tq|e @ric
c l,Cl,NMq. mokcuLr eaghr ir 313- l.
h is 6indy y.llowish *hirc ro ligl'r b€ige.
viftdly odod.$, rluble ir wat r, alcohol,
f,dnyl al@hol diglrtly elubl. in &.1onn
iNlubL in .d6, chlobfdn ed dilut Gid.
(9 l. llbiplknylF.dic rid, 2 fl'|l)@.ncrhyl ed (!) 2.(2.
Aumbiph.nyl-4.y1)prpiaic
cDHlrFo. ool.culo wigh. is 2rl4.rg,
whne b dighdy yellop, cryr.ltirc
Powdr, exirl .r ! tuemt of tho two
optcal ism.ri irslublc in wrt r, ftely
sluble ii !l..lbl, .rner, aon.. m.rhmot Md
rid, CDH'P), Nhir.. .rysllin.
r'r'-f'-"
(2i&2-14{2-n.dtlpmpyD phdyupoFmic
powder or cdoudd .ry$ti Ptuticdly
irslubl. in Mt r, frly $l!bl. in
oeloe, m..heol .!d m.thyl.n
ohldirle, Il di.slves in dild€ &lulions oialt li
2-(2iniDcrhyl phoyl mjnol b@i.
eid odl N- (2,3-rylayl) rdlErilie eid
nolall& rci3hr is 241.1, el Ed
dnd whit oddl6 micetsdlinc
pow.r.r, en h4twpiq inslubk in
hyddides ad @boml4.
qrter, solubl. in olcohol, nerlyl ilcohol, spannsly iolubl. in dhn md
Meloxien i! 4-hydrcxy,2.hodyl,N{5,nelhyl-l.Srhiuol2-yD-2 H.1,2bgmrhiuiFlraboxmidcl,
liioxid.
havj4 l5l 8 noloLr eiShr Prldi.,lly Frri
iMlubl. in ldr, :lishrt $tubk in eroft,
2l