Clw@terizclon of tL*Mi. ,1cid in Di&tu',t Pho@dicd Dotuge Fw.d tn ...

Hist.oc./melabolic s}t'dmne, which confen a p.diculdly high nsk of cardiovdculd d.aih.
CeIMlly.tiab€1e e.llitu c.mt b. culd bui only @!iroll.d. Curutly &ailablc glucG
lowing a8ats v..y @triddally i! th.n .bil y ro rldu e mic@lbdindi4 Tbe
sullbnyluo sppq to hav. cflet on nidoalbuinuia expEsed d udndy
alhmidcMtirim Etio, *trile iltc rhi@lidiclioG b.ve sic@ e$dr on rhis isk f&bi
in pa'all.l qilh dEn ef.cts or iGulir 6isl.@ {rtq.
NtDDLk yl6t d l* itudiN 11911
NN- dim.lhylimidodiqrbonimidio dimide, I,l -dim.rhylbraumid.r
C.HrClNjj FEly slublc in rlc.,
tlighdy elubl. in .Lohol, Fdielly
inelubl. in &.tonc .nd in m.rhyl.n.
ohlorid., m.ltin8 poinl is 222 - 226
l-[a-[2'ft 5+hl@2{rhdybd"iyl)dnino]anylp66ylFulphonyll-3-
.ycloh.xyluEr, crHrclNrors; wnn.
or dmosl *hit, ciysrlllire pdwd.r,
pncriolly iNoluble in w!l.., sparingly
$lublc in m.tftylec cnbiL, stghly
slubL in .LdDl dd s.rlml.
isoquinolyl)chyll
D E&ltLl ...1 tre .LEdt!
c'HjNrOlS; *hit. or rlmo{
shia po[d.r, pdci€lly iMlublc in
(96%) &d ir h.rh.!ol, elubL
i d!':i:C
rTr--
uLr ; dighdy $luble in ethool
i. .@rc, fi*ly slubl. in
Mindls esenli{l 10 hcdtb @ inrclv€d in Fifotuing r&ious fiNlioE in body. thcy re
oslly adhinil&Ed, s wll alonS wilh ditreHt food ddnk or 6 drugs, Tl|n defici.ncr oi
ex6 My lad ro vsrioE dilrub'l6 b body. Irs. N .bout l?-20 (d.pdding oi dE
$t@) niffids @Nn|a .ssd.l ro hl||@.utrition.
Mircds e genmlly clssified ar Major or b.N nimr.k de ond rcfeftd b a 6&ntial
niadis rquir€d in mouls ol l0{ bg or mrc ps d!t. nE$ @ catcim. chlorid€,
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