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Influence of Maternal Prenatal Vitamin D Status on Infant Oral Health

Influence of Maternal Prenatal Vitamin D Status on Infant Oral Health

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time <str<strong>on</strong>g>of</str<strong>on</strong>g> recruitment was 4.0 ± 2.2 pers<strong>on</strong>s. Most (92.2%) had not completed high school<br />

and <strong>on</strong>ly 2.3% had pursued some post-sec<strong>on</strong>dary educati<strong>on</strong>.<br />

Serum Results<br />

Serum analysis c<strong>on</strong>stituted an essential comp<strong>on</strong>ent <str<strong>on</strong>g>of</str<strong>on</strong>g> this study. Enrolled participants<br />

had serum samples drawn during pregnancy to assess circulating levels <str<strong>on</strong>g>of</str<strong>on</strong>g> 25(OH)D<br />

(nmol/L), total calcium (mmol/L), inorganic phosphorus (mmol/L), and alkaline<br />

phosphatase (U/L). Complete laboratory results were available for a total <str<strong>on</strong>g>of</str<strong>on</strong>g> 200 <str<strong>on</strong>g>of</str<strong>on</strong>g> the<br />

women enrolled into this study. Thus, results from seven women were missing. Some<br />

samples were lost due to delays in sending samples to the Department <str<strong>on</strong>g>of</str<strong>on</strong>g> Biochemistry<br />

and Genetics Laboratory or a missed venipuncture (Table 3.5). However, serum<br />

25(OH)D was the main metabolite <str<strong>on</strong>g>of</str<strong>on</strong>g> interest and results were available for 200 <str<strong>on</strong>g>of</str<strong>on</strong>g> the<br />

women enrolled into the study.<br />

All reports were sent to <strong>on</strong>e <str<strong>on</strong>g>of</str<strong>on</strong>g> the co-investigators (Dr. Michael M<str<strong>on</strong>g>of</str<strong>on</strong>g>fatt) rather<br />

than to the principal investigator in order to ensure that the primary investigator was<br />

blinded to the 25(OH)D status <str<strong>on</strong>g>of</str<strong>on</strong>g> the mother. This was important so as not to bias or<br />

influence the future dental examinati<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> the infant at 12 m<strong>on</strong>ths <str<strong>on</strong>g>of</str<strong>on</strong>g> age.<br />

3-8

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