Influence of Maternal Prenatal Vitamin D Status on Infant Oral Health

Table 3.6– <strong>Prenatal</strong> serum concentrations <strong>of</strong> metabolites <strong>of</strong> interest
Assay Range <strong>of</strong> Normal * Number Mean ±
S.D.
25(OH)D
(nmol/L)
35 – 105 (winter)
37 – 200 (summer)
Range
Median
200 48.1 ± 24.4 4.7 – 145 43.0
Calcium
(mmol/L)
2.10 – 2.60 198 2.25 ± 0.10 2.01 – 2.57 2.24
Phosphate
(mmol/L)
1.29 – 2.26 ( 16 years)
200 1.15 ± 0.19 0.69 – 2.28 1.16
Alkaline
Phosphatase
(U/L)
59 – 422 (≤ 17 years)
30 – 120 (> 17 years)
200 97.9 ± 51.8 34.0 – 372.0 80.0
* Department <strong>of</strong> Biochemistry and Genetics Laboratory reference values
Table 3.7 – Distribution <strong>of</strong> participants by vitamin D thresholds
25(OH)D Threshold Number <strong>of</strong> Participants Valid %
< 25 nmol/L 29 14.5
≤ 35 nmol/L 70 35.0
< 37.5 nmol/L 79 39.5
≤ 40 nmol/L 93 46.5
< 80 nmol/L 180 90.0
Infant Questionnaire
135 infants returned with their mother or primary caregiver for the second phase <strong>of</strong> this
prospective study. Overall, 64.3% (n=133) <strong>of</strong> the cohort was maintained while 74
women, along with their infant(s) were lost to follow-up. Two <strong>of</strong> the mothers continuing
in the study had twins, thus 135 infants participated in this phase <strong>of</strong> the investigation. The
average age was 16.1 ± 7.4 months and ranged from 11 to 46 months. The median age
3-10