Influence of Maternal Prenatal Vitamin D Status on Infant Oral Health

Implicated Risk
Factor
Factors associated
with low socioeconomic
status
(SES)
Developmental Defects <strong>of</strong> Enamel (DDE)
Primary Dentition
Permanent Dentition
Other (continued):
Enamel hypoplasia 80
The following section informally assesses the strength <strong>of</strong> the evidence <strong>of</strong> risk
factors with DDE according to the Canadian Guide to Clinical Preventive Health Care
from the Canadian Task Force on the Periodic Health Examination (Table 1.2-3).
Table 1.2-3 – Levels <strong>of</strong> Evidence according to the Canadian Guide to Clinical Preventive
Health Care 81
I Evidence from at least one properly randomized controlled trial
II-1
II-2
II-3
III
Evidence from well-designed controlled trials without randomization
Evidence from well-designed cohort or case-control studies
Evidence from comparisons between times or places with or without intervention
Opinions <strong>of</strong> respected authorities, based on clinical experience, descriptive
studies or reports <strong>of</strong> expert committees
Genetic Conditions
Genetic conditions are known to predispose both primary and permanent teeth to exhibit
enamel defects. 17,19 This includes amelogenesis imperfecta 17,19,20 , inherited conditions
whose manifestations include dental defects (e.g. ectodermal dysplasia 21 ), and tuberous
sclerosis 22 .
1.2-11