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Influence of Maternal Prenatal Vitamin D Status on Infant Oral Health

Influence of Maternal Prenatal Vitamin D Status on Infant Oral Health

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70 years (66.9 nmol/L) than what is reported in this l<strong>on</strong>gitudinal cohort investigati<strong>on</strong>. 20 In<br />

general, vitamin D deficiency appears to be a growing c<strong>on</strong>cern am<strong>on</strong>g pregnant women<br />

in Canada as the ability to endogenously produce vitamin D is restricted to <strong>on</strong>ly a few<br />

m<strong>on</strong>ths during the summer. The need for vitamin D supplementati<strong>on</strong> is quite apparent. In<br />

additi<strong>on</strong>, these participants may have future increased risk for other chr<strong>on</strong>ic health<br />

c<strong>on</strong>diti<strong>on</strong>s. 21<br />

Many participants exhibited vitamin D levels c<strong>on</strong>sistent with vitamin D<br />

deficiency, depending <strong>on</strong> the different thresholds proposed. A recent recommendati<strong>on</strong> to<br />

adopt values < 80 nmol/L as evidence <str<strong>on</strong>g>of</str<strong>on</strong>g> vitamin D deficieny is based <strong>on</strong> the inverse<br />

relati<strong>on</strong>ship between 25(OH)D and parathyroid horm<strong>on</strong>e (PTH) levels; the threshold<br />

where PTH levels begin to plateau. When this threshold was applied to our participants,<br />

90% were found to have deficient c<strong>on</strong>centrati<strong>on</strong>s. This is somewhat alarming given the<br />

fact that the developing fetus is entirely dependent <strong>on</strong> maternal vitamin D c<strong>on</strong>centrati<strong>on</strong>s.<br />

However, even when the different thresholds for deficiency that appeared in Chapter 3<br />

were applied there were still a c<strong>on</strong>siderable proporti<strong>on</strong> <str<strong>on</strong>g>of</str<strong>on</strong>g> participants that had levels in<br />

the deficient range; 46.5% (≤ 40 nmol/L) and 35.0% (≤ 35 nmol/L).<br />

Questi<strong>on</strong>naire resp<strong>on</strong>ses relating to milk c<strong>on</strong>sumpti<strong>on</strong> were encouraging since it is<br />

vitamin D fortified. Half <str<strong>on</strong>g>of</str<strong>on</strong>g> those women recruited into this study were c<strong>on</strong>suming milk<br />

<strong>on</strong> a daily basis while another <strong>on</strong>e-third was drinking milk a few times per week. This is a<br />

positive sign c<strong>on</strong>sidering c<strong>on</strong>cerns over possible lactose intolerance in some Aboriginal<br />

populati<strong>on</strong>s. Milk is a good source <str<strong>on</strong>g>of</str<strong>on</strong>g> vitamin D for women residing in urban centres,<br />

where milk is generally affordable compared with extreme prices in the northern regi<strong>on</strong>s<br />

<str<strong>on</strong>g>of</str<strong>on</strong>g> Canada. 22 Apart from dietary supplements, milk use may be a good means <str<strong>on</strong>g>of</str<strong>on</strong>g> obtaining<br />

6-5

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