2011 (SBTE) 25th Annual Meeting Proceedings - International ...

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L.A. Silva. 2011. Local Effect of the Conceptus on Uterine Vascular Perfusion and Remodeling during Early Pregnancy in Mares - New Findings by Doppler Ultrasonography. Acta Scientiae Veterinariae. 39(Suppl 1): s123 - s134. 14 Gastal M.O., Gastal E.L., Kot,K. & Ginther O.J. 1996. Factors related to the time of fixation of the conceptus in mares. Theriogenology. 46(7): 1171-1180. 15 Ginther O.J. 1983. Mobility of the early equine conceptus. Theriogenology. 19(4): 603-611. 16 Ginther O.J. 1983. Fixation and orientation of the early equine conceptus. Theriogenology. 19(4): 613-623. 17 Ginther O.J. 1985. Dynamic physical interactions between the equine embryo and uterus. Equine Veterinary Journal. 3(Suppl 1): 41-47. 18 Ginther O.J. 1992. Reproductive biology of the mare, basic and applied aspects. 2nd edn. Cross Plains: Equiservices Publishing, pp.1-40 and 173-290. 19 Ginther O.J. 2007. Ultrasonic Imaging and Animal Reproduction: Color-Doppler Ultrasonography - Book 4. Cross Plains: Equiservices Publishing, 752p. 20 Ginther O.J., Gastal E.L., Gastal M.O. & Beg M.A. 2005. Regulation of circulating gonadotropins by the negative effects of ovarian hormones in mares. Biology of Reproduction. 73(2): 315-323. 21 Ginther O.J. & Silva L.A. 2006. Incidence and nature of disorientation of the embryo proper and spontaneous correction in mares. Journal of Equine Veterinary Science. 26: 249-256. 22 Ginther O.J. & Utt M.D. 2004. Doppler ultrasound in equine reproduction: principles, techniques, and potential. Journal of Equine Veterinary Science. 24: 516-526. 23 Girling J.E. & Rogers P.A.W. 2005. Recent advances in endometrial angiogenesis research. Angiogenesis. 8(2): 89-99. 24 Griffin P.G. & Ginther O.J. 1993. Effects of the embryo on uterine morphology and function in mares. Animal Reproduction Science. 31: 311-329. 25 Leith G.S. & Ginther O.J. 1984. Characterization of intrauterine mobility of the early conceptus. Theriogenology. 22(4): 401-408. 26 McDowell K.J., Sharp D.C., Grubaugh W., Thatcher W.W. & Wilcox C.J. 1988. Restricted conceptus mobility results in failure of pregnancy maintenance in mares. Biology of Reproduction. 39(2): 340-348. 27 Mclean J.M. 1987. Early embryo loss. The Lancet. 329: 1033-1034. 28 Mossman H.W. 1971. Orientation and site of attachment of the blastocyst: A comparative study. In: The Biology of the Blastocyst. Blandau R.J. (Ed). Chicago: Chicago Press, pp.27-48. 29 Mossman H.W. 1987. In: Vertebrate Fetal Membranes. New Brunswick: Rutgers University Press, pp.79-83. 30 Reynolds L.P., Magness R.R. & Ford S.P. 1984. Uterine blood flow during early pregnancy in ewes: interaction between the conceptus and the ovary bearing the corpus luteum. Journal of Animal Science. 58(2): 423-429. 31 Roberts R.M., Xie S. & Mathialagan N. 1996. Maternal recognition of pregnancy. Biology of Reproduction. 54: 294-302. 32 Sharp D.C. 2000. The early fetal life of the equine conceptus. Animal Reproduction Science. 60–61: 679-689. 33 Silva L.A., Gastal E.L., Beg M.A. & Ginther O.J. 2005. Changes in vascular perfusion of the endometrium in association with changes in location of the embryonic vesicle in mares. Biology of Reproduction. 72(3): 755-761. 34 Silva L.A. & Ginther O.J. 2006. An early endometrial vascular indicator of completed orientation of the embryo and the role of dorsal endometrial encroachment in mares. Biology of Reproduction. 74(2): 337-343. 35 Silva L.A. & Ginther O.J. 2010. Local effect of the conceptus on uterine vascular perfusion during early pregnancy in heifers. Reproduction. 139(2): 453-463. 36 Silva L.A., Klein C., Ealy A.D. & Sharp D.C. 2011. Conceptus-mediated endometrial vascular changes during early pregnancy in mares - An anatomic, histomorphometric and vascular endothelial growth factor-receptor system immunolocalization and gene expression study. Reproduction. [in press]. 37 Vanderwall D.K. 2008. Early Embryonic Loss in the Mare. Biology of Reproduction. 28: 691-702. 38 Weber J.A., Freeman D.A., Vanderwall D.K. & Woods G.L. 1991. Prostraglandin E 2 secretion by oviductal transportstage equine embryos. Biology of Reproduction. 45(4): 540-543. 39 Woods G.L., Baker C.B., Baldwin J.L., Ball B.A., Bilinski J., Cooper W.L., Ley W.B., Mank E.C. & Erb H.N. 1987. Early pregnancy loss in brood mares. Journal of Reproduction and Fertility. 35(Suppl 1): 455-459. www.ufrgs.br/actavet 39 (Suppl 1) s134
M.M. Franc anco, A. Pellegr ellegrin, R.A. Figueir igueiredo edo, et al. 2011. The Innovation Network in Animal Reproduction: EMBRAPA’s Experience in Organizing a Research Project on Reprodutive... Acta Scientiae Veterinariae. 39(Suppl 1): s135 - s138. Acta Scientiae Veterinariae, 2011. 39(Suppl 1): s135 - s138. ISSN 1679-9216 (Online) The Innovation Net etwor ork in Animal Repr eproduc duction: EMBRAP APA’s s Exper erienc ience e in Organizing a Research Project on Reproductive Biotechnology Maurício Machain Franco, Aiesca Pellegrin, Ricardo Alamino Figueiredo, Alexandre Rossetto Garcia, Luiz Sergio Almeida Camargo, Hymerson Costa Azevedo & João Henrique Moreira Viana ABSTRACT Background: In 2007 a broad Network project was proposed, aiming to organize in a more efficient way the different research and development actions related to new reproductive technologies in Embrapa. The initial proposal focused to develop new technological solutions to increase Brazilian livestock competitiveness; generate basic knowledge to support development of new technologies; to promote genetic improvement and evaluate dairy and beef animal models for the different ecosystems, to improve laboratorial infrastructure and promote capacity building; and to promote equal development of the technologies for the different livestock species. The final proposal, titled “Innovation Network in Animal Reproduction” was approved for the period 2008-2012. Review: The Network Project includes research activities in animal reproduction and in the interfaces of reproduction and animal health, nutrition, and genetics. A consortium of 12 of the Embrapa units, 14 Universities, 2 International Research Centers and 5 private companies are engaged in the project. The main structure follows the general guidelines of the Embrapa´s standard of network projects, being organized in 10 thematic Component Projects (CPs): CP1- Activities related to the organization of the Network, as the coordination of the CPs, financial management, promotion of meetings and workshops, and compilation of results and evaluations; CP2 – Development and evaluation of new technologies for the sanitary control of semen, oocytes, and embryos; CP3- Evaluation of nutritional strategies to improve reproductive efficiency; CP4- Development N of methods to improve the quality and quantity of gametes used in assisted reproductive technologies; CP5- Development of in vivo and in vitro embryo production systems; CP6- Establishment of protocols for the isolation, culture and maintenance of cell lines aiming the production of animal clones; CP7- Establishment of alternative protocols to the production of transgenic or intragenic animals; CP8- Identification, selection, use and conservation of genetic resources; CP9- Validation and monitoring of technologies; CP10- Technological innovation. Conclusions: The establishment of the network allowed the organization of Embrapa’s different ongoing research actions in animal reproduction in a large and multidisciplinary project. As consequences, there was a larger interaction among the different research groups of the company and external partners. The proposal of collaborative research improved the scientific production of the group and also the development of products, processes, and technical information to the private sector. The technology transference and capacity building activities were strategically reorganized in line with the scope of the Network Project. A last consequence of the network was the possibility of applying for consortium research funding opportunities. The group also expects to improve scientific collaboration and to increase the relevance of R&D projects in animal reproduction, to improve the interplay with the government agencies in charge of the establishment of laws and rules for reproductive biotechnology used in livestock, and to improve their capacity of identifying and measuring the impact of the new technologies in the different livestock production systems. Keywords: Network research, embryo technologies, R&D projects. Brazilian Agricultural Research Corporation. CORRESPONDENCE: J.H.M. Viana [jhmviana@cnpgl.embrapa.br - FAX: +55 (32) 3249- 4701]. Rua Eugênio do Nascimento n. 610, Dom Bosco. CEP 36038-330 Juiz de Fora, MG, Brazil. s135
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