N-(1,3-Dimethylbutyl)-N
N-(1,3-Dimethylbutyl)-N
N-(1,3-Dimethylbutyl)-N
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OECD SIDS<br />
N-(1,3-DIMETHYLBUTYL)-N´-PHENYL-1,4-PHENYLENEDIAMINE<br />
5. TOXICITY ID: 793-24-8<br />
DATE: 11.05.2005<br />
Year : 1976<br />
GLP : no data<br />
Test substance : no data<br />
Reliability : (4) not assignable<br />
Cited from BUA report no 208 (1996)<br />
No further information available<br />
28.08.2001 (90)<br />
Type : Cytogenetic assay<br />
System of testing : Chinese hamster ovary cells (CHO)<br />
Test concentration : no data<br />
Cycotoxic concentr. : no data<br />
Metabolic activation : no data<br />
Result : negative<br />
Method : other<br />
Year : 1987<br />
GLP : no data<br />
Test substance : no data<br />
Reliability : (4) not assignable<br />
Documentation insufficient for assessment<br />
Only results were given<br />
28.08.2001 (91)<br />
Type : Cytogenetic assay<br />
System of testing : Chinese hamster ovary cells (CHO)<br />
Test concentration : up to 15 ug/ml<br />
Cycotoxic concentr. : no data<br />
Metabolic activation : with and without<br />
Result :<br />
Method : other<br />
Year : 1987<br />
GLP : no data<br />
Test substance : no data<br />
Result : without S-9 mix: negative<br />
with S-9 mix: Increased aberration rates were occasionally<br />
induced at 5-15 ug/ml (preparatory times of 6-24 hrs).<br />
However, these effects were not concentration-dependent and<br />
were always linked to drastic cytotoxicity, so that the<br />
overall result was equivocal.<br />
Reliability : (4) not assignable<br />
Cited from BUA report no 208 (1996)<br />
No further information available<br />
28.08.2001 (92)<br />
Type : Mouse lymphoma assay<br />
System of testing : L5178Y TK mouse lymphoma cells<br />
Test concentration : up to 4 ug/ml (without S-9 mix); up to 33 ug/ml (with S-9 mix)<br />
Cycotoxic concentr. : no data<br />
Metabolic activation : with and without<br />
Result : negative<br />
Method : other<br />
Year : 1976<br />
GLP : no data<br />
Test substance : no data<br />
Reliability : (4) not assignable<br />
Cited from BUA report no 208 (1996)<br />
UNEP PUBLICATIONS 119