N-(1,3-Dimethylbutyl)-N
N-(1,3-Dimethylbutyl)-N
N-(1,3-Dimethylbutyl)-N
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OECD SIDS<br />
N-(1,3-DIMETHYLBUTYL)-N´-PHENYL-1,4-PHENYLENEDIAMINE<br />
5. TOXICITY ID: 793-24-8<br />
DATE: 11.05.2005<br />
Number of animals : 6<br />
Vehicle :<br />
PDII :<br />
Result : not irritating<br />
Classification :<br />
Method : other<br />
Year : 1973<br />
GLP : no data<br />
Test substance : other TS: purity 95.7 %<br />
Result : AVERAGE SCORE<br />
0.0/8.0<br />
Test condition : TEST ANIMALS:<br />
-Strain: New Zealand albino<br />
-Sex: Male/female<br />
-Number of animals: 6<br />
ADMINISTRATION/EXPOSURE<br />
-Preparation of test substance: undiluted<br />
-Area of exposure: no data<br />
-Occlusion: semiocclusive<br />
-Postexposure period: 7 d<br />
-Removal of test substance: after 24 hours<br />
EXAMINATIONS<br />
-Scoring system: Federal Hazardous Substance Act 21 CFR, §<br />
191.11 (1964)<br />
-Examination time points: no data<br />
Reliability : (2) valid with restrictions<br />
Study meets generally accepted scientific principles,<br />
data from summary without detailed documentation, acceptable<br />
for assessment<br />
Flag : Critical study for SIDS endpoint<br />
04.10.2001 (57)<br />
Species : rabbit<br />
Concentration : .5 other: mg (undiluted)<br />
Exposure : no data<br />
Exposure time :<br />
Number of animals : 6<br />
Vehicle :<br />
PDII : 3.3<br />
Result : moderately irritating<br />
Classification :<br />
Method : Draize Test<br />
Year : 1977<br />
GLP : no data<br />
Test substance : no data<br />
Result : Primary cutaneous irritation index:<br />
3.3; classified as medium irritant potential<br />
REVERSIBILITY:<br />
yes<br />
OTHER EFFECTS:<br />
no skin necrosis<br />
Test condition : TEST ANIMALS:<br />
-Strain: New Zealand<br />
-Sex: female<br />
-Weight at study initiation: 2.4-2.7 kg<br />
UNEP PUBLICATIONS 97