N-(1,3-Dimethylbutyl)-N

OECD SIDS
N-(1,3-DIMETHYLBUTYL)-N´-PHENYL-1,4-PHENYLENEDIAMINE
4. ECOTOXICITY ID: 793-24-8
DATE: 11.05.2005
Unit : mg/l
EC50 : 420
Method : ISO 8192 "Test for inhibition of oxygen consumption by activated sludge"
Year : 1984
GLP : no
Test substance : other TS: technical grade 6PPD
Reliability : (4) not assignable
Original reference not available
04.11.2004 (55)
4.5.1 CHRONIC TOXICITY TO FISH
4.5.2 CHRONIC TOXICITY TO AQUATIC INVERTEBRATES
4.6.1 TOXICITY TO SEDIMENT DWELLING ORGANISMS
4.6.2 TOXICITY TO TERRESTRIAL PLANTS
Species : Lactuca sativa (Dicotyledon)
Endpoint : growth
Exposure period : 14 day(s)
Unit : mg/l
EC50 : ca. .5 calculated
Method : other: calculation
Year : 1993
GLP :
Test substance : other TS: various chloroanilines and other compounds, but not 6PPD
Method : OECD Guide-line 208 was used to derive QSAR, which was used to
calculate phytotoxicity of 6PPD. 6PPD was not measured.
Remark : Lactuca sativa Ravel R2
Result : The 14 d EC50 of Lactuca sativa was measured for various chloroanilines
and other compounds, but not with 6PPD. An equation for the calculation of
the EC was derived (log EC50 = -0.46 log Kow + 2.38 [µmol/l]), which was
used to calculate the EC50 of 6PPD (Log kow = 4.68) to be about 0.5 mg/l.
Test condition : - 10 Seeds per tray. Trays covered with glass plates. Temperature 21 °C,
photoperiod 16 h light / 8 h dark, light intensity 6500 lux, humidity 40 - 80 %
- 6PPD was not tested but wide range of other chloroanilines and other
compounds
- The authors derived an equation for the QSAR for the relationship
between log EC50 (µmol/l) and the log Kow:
EC50 = -0.46 log Kow + 2.38 [µmol/l]
- Using this equation (Log kow = 4.68), the EC50 was calculated to be
about 0.5 mg/l
Reliability : (2) valid with restrictions
Accepted calculation method
05.11.2004
4.6.3 TOXICITY TO SOIL DWELLING ORGANISMS
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