N-(1,3-Dimethylbutyl)-N

OECD SIDS
N-(1,3-DIMETHYLBUTYL)-N´-PHENYL-1,4-PHENYLENEDIAMINE
5. TOXICITY ID: 793-24-8
DATE: 11.05.2005
-Observation period: 1, 4, 24, 48, 72, 120 h
Reliability : (2) valid with restrictions
Study meets generally accepted scientific principles,
data from summary without detailed documentation, acceptable
for assessment
Flag : Critical study for SIDS endpoint
04.10.2001 (56)
Species : rabbit
Concentration : undiluted
Dose : .1 ml
Exposure time :
Comment : no data
Number of animals : 6
Vehicle : none
Result : slightly irritating
Classification :
Method : other: see ME
Year : 1973
GLP : no data
Test substance : other TS: purity 95.7 %
Method : 0.1 ml was placed into the conjunctival sac, observation
period 7 days, scoring in accordance with the Federal
Hazardous Substance Act, 21 CFR, paragraph 191.12 (1964)
Result : AVERAGE SCORE:
1.2/110
Test condition : TEST ANIMALS:
-Strain: New Zealand albino
-Sex: male/female
ADMINISTRATION/EXPOSURE:
-Postexposure period: 7 d
EXAMINATIONS:
-Scoring system: Federal Hazardous Substance Act 21 CFR, §
191.11 (1964)
Reliability : (2) valid with restrictions
Study meets generally accepted scientific principles,
data from summary without detailed documentation, acceptable
for assessment
Flag : Critical study for SIDS endpoint
04.10.2001 (57)
5.3 SENSITIZATION
Type : Guinea pig maximization test
Species : guinea pig
Concentration : 1 st : Induction .5 % intracutaneous
2 nd : Challenge .05 % open epicutaneous
3 rd : Challenge .5 % open epicutaneous
Number of animals : 20
Vehicle : other: olive oil and petrolatum
Result : sensitizing
Classification :
Method : other: according to Magnusson & Kligman (1969)
Year : 1977
GLP : no data
Test substance : no data
UNEP PUBLICATIONS 99