N-(1,3-Dimethylbutyl)-N

OECD SIDS
N-(1,3-DIMETHYLBUTYL)-N´-PHENYL-1,4-PHENYLENEDIAMINE
5. TOXICITY ID: 793-24-8
DATE: 11.05.2005
27.08.2001 (61)
5.1.2 ACUTE INHALATION TOXICITY
5.1.3 ACUTE DERMAL TOXICITY
Type : LD50
Value : > 7940 mg/kg bw
Species : rabbit
Strain : New Zealand white
Sex : no data
Number of animals : 2
Vehicle : no data
Doses :
Method : other
Year : 1973
GLP : no data
Test substance : other TS: purity 95.7 %
Result : MORTALITY:
-Number of deaths at each dose: no deaths
CLINICAL SIGNS:
reduced appetite and activity for 3-7 days
NECROPSY FINDINGS:
viscera appeared normal
Test condition : ADMINISTRATION:
-Occlusion: semi-occlusive dressing to clipped intact skin
-Doses: 3160, 5010, 7940 mg/kg
-Removal of test substance: after 24 hours
EXAMINATIONS:
14 day post-observation period: clinical symptoms, autopsy
Reliability : (2) valid with restrictions
Study meets generally accepted scientific principles,
data from summary without detailed documentation, acceptable
for assessment
Flag : Critical study for SIDS endpoint
04.10.2001 (57)
Type : LDLo
Value : = 3160 - 5010 mg/kg bw
Species : rabbit
Strain : New Zealand white
Sex : female
Number of animals : 1
Vehicle :
Doses : 798, 1260, 2000, 3160, 5010, 7980 mg/kg bw
Method : other
Year : 1962
GLP : no data
Test substance : other TS: undiluted
Result : MORTALITY:
-Time of death: survival 10-11 d
-Number of deaths at each dose: 0/1, 0/1, 0/1, 0/1, 1/1, 1/1
94
UNEP PUBLICATIONS