ABSTRACTS from 16th International COnference on ... - CRRT Online

<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT,
SAN DIEGO, FEB 14-17, 2012
correction of serum sodium may result in
the development of osmotic
demyelination, typically noted at rates of
correction that exceed 12 mmol per liter
in 24 hrs or 19 mmol per liter in 48
hours. {Adrogue, 2 #322} In this study,
we examined the effect of dialysis
intensity on the rate of rise in serum
sodium in patients with acute kidney
injury initiated on continuous
venovenous hemodialysis (CVVHD).
Methods: Retrospective study of 35
critically ill patients with acute kidney
injury and serum sodium less than 13
mmol/L at initiation of CVVHD.
Results: Mean age was 64±13 years; 2
(56%) were male and 16 (44%) had
baseline kidney disease. APACHE II
score on ICU admission was 2±1, 23
(64%) were on mechanical ventilation
and 2 (56%) were on vasopressor
support. Serum sodium at time of
CVVHD initiation was 125±4 mmol/L,
creatinine 4.6±2 mg/dl, and BUN 91±32.
In simple linear regression model, a 1
ml/kg/hr increase in dialysis dose
(assessed by effluent rate) was
associated with 4.5 mmol/L increase in
serum sodium over twenty four hours
(p=.9). Gender or baseline weight did
not alter the above parameter estimate or
the p value in a multivariable model.
Conclusion: CVVHD can correct low
serum sodium levels in a safe, effective,
and controlled manner. Each 1 ml/kg/hr
increase in dialysis intensity results in a
4.5 mmol/L rise in serum sodium.
3. Acute Kidney Injury; The
Experience From The Other Side
Of The World
Che Rosle D, Farez Safhan Mn, Mohd
Ramli S, Norasmiza Am, Azrel Shahreez
Ag, Khairul Anuar H
<strong>International</strong> Islamic University
Malaysia, Hospital Tengku Ampuan
Afzan, Kuantan, Malaysia
Introduction: AKI is commonly
diagnosed and the mortality rate was
extremely high. At least a third of AKI
patients required dialysis however,
CRRT is not widely available especially
in under-developed countries. Hence,
conventional hemodialysis was the only
available option. Objectives: To define
the clinical approach and determine the
outcomes of our AKI patients. Method:
This is a single centre, sub-urban
satellite hospital's experience in the
management of AKI patients. The 3-
days mortality rate and renal outcomes
were estimated and prognostic factors
associated with clinical outcomes were
also identified. Results: 75 patients were
reviewed and their mean age was 52.9
+/- 14.5 years-old. Two-third were males
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