ABSTRACTS from 16th International COnference on ... - CRRT Online

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Nishimura R, Ornato JP, Page RL, Riegel B. ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction-Executive Summary A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction) Developed in Collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol. 2007 Aug 14;50(7):652-726. 8. Katholi RE, Woods WT, Jr., Taylor GJ, et al: Oxygen free radicals and contrast induced nephropathy. Am J Kidney Dis 32:64-71,1998 9. ACT Investigators. Acetylcysteine for prevention of renal outcomes in patients undergoing coronary and peripheral vascular angiography: main results <strong>from</strong> the randomized Acetylcysteine for Contrast-induced nephropathy Trial (ACT). Circulation. 2011 Sep 13;124(11):1250-9. Epub 2011 Aug 22. PubMed PMID: 21859972. 33
Distant Organ Responses in AKI Hamid Rabb MD 5:15-5:30 Wednesday, February 15 Educational Objectives: 1. Describe scope of the clinical problem of distant organ dysfunction during AKI 2. Present the evidence supporting kidney-distant organ cross-talk in acute kidney injury 3. Describe newly recognized mechanisms and pathways that underlie this syndrome Content Description: Acute lung injury (ALI) requiring mechanical ventilation is commonly associated with AKI, and lung dysfunction is highly correlated with death in the patient with AKI. Astute clinicians have recognized that pulmonary symptoms occur frequently with renal failure, and that the degree of pulmonary dysfunction appears to exceed that purely attributable to fluid overload. Despite the close clinical linkage of ALI and AKI, there is little mechanistic information regarding how these organs interact in the critically ill patient. Recent data has unveiled a role for inflammatory mediators and electrolyte transporter abnormalities in accentuating the vicious cycle of kidneylung injury. Furthermore, injurious lung ventilation strategies likely predispose the kidney to additional insults by amplifying inflammatory and pro-apoptotic pathways. AKI also has a direct effect on brain function as well as effects on liver and heart. An improved understanding of the mechanisms and pathways that mediate AKI induced distant organ dysfunction is important so that we can develop dialysis as well as other strategies to improve the high morbidity and mortality during AKI. Suggested Reading: 1. Kramer A, Postler G, Salhab K, Mendez C, Carey L, Rabb H. Renal ischemia/reperfusion leads to macrophage-mediated increase in pulmonary vascular permeability. Kidney Int 55:2362-7, 1999 2. Pannu N, Mehta RL Mechanical ventilation and renal function: an area for concern? Am J Kidney Dis 39:616-24, 2002 3. Imai Y, Parodo J, Kajikawa O, de Perrot M, Fischer S, Edwards V, Cutz E, Liu M, Keshavjee S, Martin TR, Marshall JC, Ranieri VM, Slutsky AS . Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA 289:2104-12, 2003 4. Hoke TS, Douglas IS, Klein CL, He Z, Fang W, Thurman JM, Tao Y, Dursun B, Voelkel NF, Edelstein CL, Faubel S. Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury. J Am Soc Nephrol 18: 155-64, 2007. 5. Liu M, Liang Y, Chigurupati S, Lathia JD, Pletnikov M, Sun Z, Crow M, Ross CA, Mattson MP, Rabb H. Acute kidney injury leads to inflammation and functional changes in the brain. J Am Soc Nephrol 19:1360-70, 2008 6. Hassoun HT, Lie ML, Grigoryev DN, Liu M, Tuder RM, Rabb H. Kidney ischemia-reperfusion injury induces caspase-dependent pulmonary apoptosis. Am J Physiol Renal. 297:F125-37, 2009 7. Golab F, Kadkhodaee M, Zahmatkesh M, Hedayati M, Arab H, Schuster R, Zahedi K, Lentsch AB, Soleimani M. Ischemic and non-ischemic acute kidney injury cause hepatic damage. Kidney Int 75:783-92, 2009 8. Grams M, Rabb H. The distant organ effects of acute kidney injury. Kidney Int Aug 3(epub), 2011 34
Page 2 and 3: CRRT 2012 SEVENTEENTH INTERNATIONAL
Page 4 and 5: FACULTY DISCLOSURES CRRT 2012 Facul
Page 6 and 7: CRRT 2012 ORGANIZING COMMITTEE USA
Page 8 and 9: CRRT 2012 FACULTY Patrick Honoré,
Page 10 and 11: ACKNOWLEDGEMENTS CRRT 2012 ACKNOWLE
Page 12 and 13: PLENARY SESSIONS CRRT 2012 PROGRAM/
Page 18 and 19: WORKSHOPS CRRT 2012 PROGRAM/INDEX T
Page 20 and 21: WORKSHOPS CRRT 2012 PROGRAM/INDEX W
Page 22 and 23: POSTER ABSTRACTS C
Page 24 and 25: POSTER ABSTRACTS C
Page 26 and 27: NURSING FORUM LUNCHEON Communicatio
Page 28 and 29: Nutritional Support in ICU Patients
Page 30 and 31: Educational Objectives: The Endothe
Page 32 and 33: SPECIAL LECTURE Engineering Critica
Page 36 and 37: Do Vasoactive Drugs and Fluids Impr
Page 38 and 39: Blood Transfusions are Important fo
Page 40 and 41: Thinking Outside of the Box: A Nove
Page 42 and 43: Nursing Forum 2 Luncheon Benchmarki
Page 44 and 45: 4. Mori K, Lee HT, Rapoport D, Drex
Page 46 and 47: Differential Diagnosis of AKI: Can
Page 48 and 49: Myocardial Stunning and Brain Edema
Page 50 and 51: 4. Udy A, Roberts JA, Lipman J. Wha
Page 52 and 53: CRRT and ECMO: Techniques and Outco
Page 54 and 55: Management of Severe Heart Failure:
Page 56 and 57: Avoiding Anticoagulation for CRRT:
Page 58 and 59: Improving Outcomes from</st
Page 60 and 61: The Changing Face of AKI: Snapshots
Page 62 and 63: Alkaline Phosphatase Peter Pickkers
Page 64 and 65: creatinine (Cr) was measured using
Page 66 and 67: Surveillance and Early Recognition
Page 68 and 69: therapy admitted to general intensi
Page 70 and 71: A01 Assessing the Microcirculation
Page 72 and 73: A01 Assessing the Microcirculation
Page 74 and 75: C03 Critical Care Pharmacology: Vas
Page 76 and 77: D04 Biomarkers 1: Principles and Ap
Page 78 and 79: 6. Ferguson JW, Dover AR, Chia S, C
Page 80 and 81: G07 Fluids and Solutions in the Cri
Page 82 and 83: A09 Vascular Access /Membrane and C
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A09 Vascular Access /Membrane and C
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C11 Critical Care Management: Nutri
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D12 Biomarkers 2: Application in AK
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Educational Objectives: E13 Liver a
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G15 Fluids and Solutions in the Cri
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Educational Objectives: 1) Discuss
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B18 Fluid Management Ravindra L. Me
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C19 Acid Base and Electrolyte Probl
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D20 Extracorporeal Techniques for S
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the mediatordelivery hypothesis. In
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F22 Ensuring Patient Safety and Qua
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H24 Patient Centered Care in the IC
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B26 Starting and Stopping RRT for A
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C27 Acid Base and Electrolyte Probl
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D28 Extracorporeal Techniques for S
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E29 Heart Failure and Cardio-Renal
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F30 Ensuring Patient Safety and Qua
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H32 Withdrawing & Withholding Suppo
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Patel SS, Holley JL. Withholding an
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