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<str<strong>on</strong>g>ABSTRACTS</str<strong>on</strong>g> FROM 17 TH INTERNATIONAL CONFERENCE ON <strong>CRRT</strong>,<br />

SAN DIEGO, FEB 14-17, 2012<br />

kg), were treated over 3 m<strong>on</strong>ths <str<strong>on</strong>g>from</str<strong>on</strong>g><br />

June 29 to December 211. 8 patients<br />

were treated with CVVH and 2 with<br />

CVVHDF. Four patients had an<br />

admitting diagnosis of sepsis, four<br />

patients had liver failure, <strong>on</strong>e patient had<br />

respiratory distress post b<strong>on</strong>e marrow<br />

transplantati<strong>on</strong> and the tenth patient had<br />

Langerhans Histocytosis. Effectiveness<br />

of treatment was measured by negative<br />

fluid balance, fall in plasma<br />

urea/creatinine/amm<strong>on</strong>ia/organic acids,<br />

circuit life, circuit pressures. Eight<br />

patients had a peripherally inserted<br />

double lumen vascular access device and<br />

two patients were c<strong>on</strong>nected to an Extra<br />

Corporeal Membrane Oxygenati<strong>on</strong><br />

(ECMO) circuit. 52 treatment sessi<strong>on</strong>s<br />

were performed over 61 patient-days<br />

(range 1-26 sessi<strong>on</strong>s, mean 5.2, with 1-<br />

27 days of treatment, mean 6.1 days per<br />

patient). Heparin was used as<br />

anticoagulant for all patients, however,<br />

<strong>on</strong>e patient was changed to citrate.<br />

Blood flow was 2.5 – 6.1 ml/kg/min.<br />

CVVH with prefilter replacement fluid<br />

was standard. Effluent was 2% of blood<br />

flow. Negative or neutral fluid balance<br />

was always achieved and plasma<br />

creatinine, urea, amm<strong>on</strong>ia and organic<br />

acid values fell to steady-state within 3<br />

hours. Access pressure, filter pressure,<br />

venous return pressure and transmembrane<br />

pressure were always within<br />

acceptable ranges. Reas<strong>on</strong>s for changing<br />

circuits included routine change at 72<br />

hours, filter clotting with rising TMP or<br />

cessati<strong>on</strong> of treatment to facilitate a scan<br />

or surgical procedure. No adverse<br />

clinical events occurred as a result of<br />

CVVH. The Prismaflex ST 6 circuit is<br />

efficacious in infants as small as 8 kg.<br />

Mean circuit life for all reas<strong>on</strong>s was<br />

22.45 hours.<br />

7. Outcomes of Patients with End<br />

Stage Renal Disease (ESRD)<br />

Under Chr<strong>on</strong>ic Hemodialysis<br />

Requiring C<strong>on</strong>tinuous Renal<br />

Replacement Therapy (<strong>CRRT</strong>)<br />

and Patients without ESRD in<br />

Acute Renal Failure Requiring<br />

<strong>CRRT</strong><br />

Ye<strong>on</strong> So<strong>on</strong> Jung, Jin Hee Park, Sung Bin<br />

Kim, Ho Sik Shin, Hark Rim<br />

Kosin University College of Medicine<br />

Purpose: The purpose of this study were<br />

to (1) evaluate short-term patient<br />

survival and (2) compare the survival of<br />

c<strong>on</strong>venti<strong>on</strong>al hemodialysis (HD) patients<br />

needing <strong>CRRT</strong> with the survival of n<strong>on</strong>end<br />

stage renal disease (ESRD) patients<br />

in ARF requiring <strong>CRRT</strong>.<br />

Methods: We evaluated adults (> 18<br />

years) requiring <strong>CRRT</strong> who were treated<br />

in the intensive care unit (ICU) of Kosin<br />

University Gospel Hospital, Busan,<br />

Korea <str<strong>on</strong>g>from</str<strong>on</strong>g> January 1, 29 to December<br />

31, 21. A total of 1 (24 ESRD, 76 n<strong>on</strong>-<br />

ESRD) patients received <strong>CRRT</strong> during<br />

the study period. Patients were divided<br />

into two major groups: patients with<br />

ESRD requiring chr<strong>on</strong>ic dialysis and<br />

patients without ESRD (n<strong>on</strong>-ESRD)<br />

with ARF. Predictors of all-cause death<br />

were examined using Kaplan-Meier<br />

analysis and Cox proporti<strong>on</strong>al hazards<br />

analyses in both treatment groups.<br />

Results: Across all patients, the median<br />

survival time was 56 days, and the 9-day<br />

survival rate was 44.6%. For n<strong>on</strong>-ESRD<br />

patients, the 9-day survival rate was<br />

41.6%. For ESRD patients, the 9-day<br />

survival rate was 55.3%. Multivariate<br />

Cox proporti<strong>on</strong>al hazards analyses<br />

dem<strong>on</strong>strated that c<strong>on</strong>venti<strong>on</strong>al HD was<br />

not a significant predictor of mortality<br />

[hazard ratio (HR) .334, 95% c<strong>on</strong>fidence<br />

interval (CI) .63–1.763, P = .196], after<br />

adjustment for age, gender, presence of<br />

sepsis, APACHE score, use of<br />

126

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