ABSTRACTS from 16th International COnference on ... - CRRT Online

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<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT, SAN DIEGO, FEB 14-17, 2012 females), admitted to the Intensive Care Unit (ICU) <strong>from</strong> February to November, 211 with AKI requiring CRRT were monitored up to 5 consecutive days. All patients received CRRT using Prisma M1 set with AN69 hemofilter on citrate anticoagulation with an effluent rate of 25-3 ml/kg/hr. Data, including admission weight (WT), daily WT and daily fluid balance calculations, were obtained <strong>from</strong> electronic medical records and ICU flowsheets which were compared to physician prescription orders. Results: The mean pre-CRRT WT (99. + 25.6 kg) was markedly increased when compared to the mean admitting WT (8.2 + 24.9 kg). Mean net negative fluid balance achieved during the first 48 hours of CRRT was 36 mL, with a decrease in mean WT to 98+ 23.1 kg, however this was not statistically significant. By day 5, a mean reported fluid loss of 3.2 liters was associated with a significant mean weight reduction to 92.9+ 25.3 kg (p = .1). The mean prescribed ultrafiltration (UF) rate was 35.3+ 28.4 mL/hr while delivered UF rate was 52.7+ 48.6 mL/h(p=.2). On day 2, the mean fluid removal set on the Prisma machine was 6.5 L/day while mean net fluid removal was 6. L/day which was significantly lower (p=.3). In conclusion, actual delivered UF during CRRT treatments exceeded physician prescription orders. UF goals still need to be optimized. 28. The Effect Of Continuous Renal Replacement Therapy In Patients With Acute Kidney Injury on the serum levels of biomarkers usually used to indicate renal function Zhihong Zhang, Dehua Gong, Daxi Ji, Bin Xu, Zhihong Liu Research Insitute of Nephrology,Jinling Hospital Objective: Continuous veno-venous hemofiltration(CVVH) can affect the serum concentrations of usually used biomarkers to indicate renal function, like creatinine(Cr), urea(UN) and cystatin C(Cys-C). In this study we investigate to what extent CVVH affects the concentrations of Scr,BUN and Cys- C independent on renal function change. Methods: Eleven patients with oliguric acute kidney injury (AKI) requiring CVVH were enrolled. Four of them received CVVH at dose of 2L/hr and 7 received CVVH at dose of 4L/hr. Samples were obtained <strong>from</strong> the afferent and efferent lines of the extracorporeal circuit and <strong>from</strong> the ultrafiltrate line at 4 different time points(,4,12 and 24h) for measurement of Cr, UN and Cys C. Results: Concentrations of Scr, BUN and Cys-C before CVVH (2 L/hr) were 4.84±2.51, 57.35±31.33mg/dl and 4.34±1.33 mg/L. Levels of Scr, BUN and Cys-C at 4,12 and 24h during CVVH (2 L/hr) gradually decreased <strong>from</strong> the baseline values. The decreases of Scr, BUN and Cys-C were 49.7%,42.5% and 28.1%(all P>.5). The mean sieving coefficient of Scr,BUN and Cys-C were .89, .78 and .32;the mean clearance of Scr, BUN and Cys-C were 29.7, 26 and 1.7mL/min. Concentrations of Scr,BUN and Cys-C before CVVH (4 L/hr) were 6.9±4.13, 94.3±57.4 mg/dl and 3.7±1.4 mg/L. Levels of Scr, BUN and Cys-C at 4,12 and 24h during CVVH (4L/hr) were gradually decreased <strong>from</strong> the baseline values. The maximum decreases of Scr,BUN and Cys-C were 57.8%( P=.39),51.% and 26.6%(all P>.5). The mean the sieving coefficient of Scr, BUN and Cys-C were .82, .97and .51;the mean clearance of Scr,BUN and Cys-C were 54.7, 64.6 and34.mL/min. Conclusion: Compared with Scr and 143
<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT, SAN DIEGO, FEB 14-17, 2012 BUN, the alteration of levels of CysC caused by CVVH is slight, which suggests that it can be used to indicate the patient’s renal function change in some extent during CVVH. RESEARCH IN AKI 29. Urine Biomarkers Predict Acute Kidney Injury in Term Neonates with Perinatal Depression David J Askenazi, Rajesh Koralkar , Hayden E Hundley, Angela Montesanti, Pushkar Parwar, Srdjan Sonjara, Namasivayam Ambalavanan University of Alabama at Birmingham, University of South Alabama College of Medicine, Georgia State University Institute of Public Health, University of California San Diego Background: Acute kidney injury (AKI) is an independent risk factor for mortality in neonatal, pediatric and adult critically ill populations. As serum creatinine (SCr) is not ideal to diagnose AKI, urine AKI biomarkers may improve our ability to detect an injury early in the disease process. Objectives: To identify urine biomarkers that predict acute kidney injury (AKI) in term infants with perinatal depression (Apgar score
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CRRT 2012 SEVENTEENTH INTERNATIONAL
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FACULTY DISCLOSURES CRRT 2012 Facul
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CRRT 2012 ORGANIZING COMMITTEE USA
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CRRT 2012 FACULTY Patrick Honoré,
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ACKNOWLEDGEMENTS CRRT 2012 ACKNOWLE
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PLENARY SESSIONS CRRT 2012 PROGRAM/
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WORKSHOPS CRRT 2012 PROGRAM/INDEX T
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WORKSHOPS CRRT 2012 PROGRAM/INDEX W
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POSTER ABSTRACTS C
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POSTER ABSTRACTS C
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NURSING FORUM LUNCHEON Communicatio
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Nutritional Support in ICU Patients
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Educational Objectives: The Endothe
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SPECIAL LECTURE Engineering Critica
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Nishimura R, Ornato JP, Page RL, Ri
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Do Vasoactive Drugs and Fluids Impr
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Blood Transfusions are Important fo
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Thinking Outside of the Box: A Nove
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Nursing Forum 2 Luncheon Benchmarki
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4. Mori K, Lee HT, Rapoport D, Drex
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Differential Diagnosis of AKI: Can
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Myocardial Stunning and Brain Edema
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4. Udy A, Roberts JA, Lipman J. Wha
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CRRT and ECMO: Techniques and Outco
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Management of Severe Heart Failure:
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Avoiding Anticoagulation for CRRT:
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Improving Outcomes from</st
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The Changing Face of AKI: Snapshots
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Alkaline Phosphatase Peter Pickkers
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creatinine (Cr) was measured using
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Surveillance and Early Recognition
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therapy admitted to general intensi
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A01 Assessing the Microcirculation
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A01 Assessing the Microcirculation
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C03 Critical Care Pharmacology: Vas
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D04 Biomarkers 1: Principles and Ap
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6. Ferguson JW, Dover AR, Chia S, C
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G07 Fluids and Solutions in the Cri
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A09 Vascular Access /Membrane and C
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A09 Vascular Access /Membrane and C
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C11 Critical Care Management: Nutri
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D12 Biomarkers 2: Application in AK
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Educational Objectives: E13 Liver a
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G15 Fluids and Solutions in the Cri
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Page 114 and 115: E29 Heart Failure and Cardio-Renal
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Page 118 and 119: H32 Withdrawing & Withholding Suppo
Page 120 and 121: Patel SS, Holley JL. Withholding an
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ABSTRACTS FROM 17
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