ABSTRACTS from 16th International COnference on ... - CRRT Online

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<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT, SAN DIEGO, FEB 14-17, 2012 Patient factors potentially associated with AKI were investigated including: Apgar scores, cord pH and base deficit, delivery room complications, severity of illness (need for pressors, transfusions), and exposure to nephrotoxic medications. Results: AKI was found in 36 (38%) of 96 infants with 16, 7, and 13 fulfilling criteria for stage I, II, and III, respectively. Overall mortality was 7% for the cohort and was higher for those who suffered AKI compared to those who did not, but did not reach statistical significance (14% vs. 3%, p= .99). Patients with AKI stayed longer in the Neonatal Intensive Care unit (15.4±9.3 vs. 11±5.9 days, p=.14), and required prolonged mechanical ventilation (9.7±5.9 vs. 4.8±3.7 days, p46 ng/ml), the decreasing group (the 157
<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT, SAN DIEGO, FEB 14-17, 2012 lowest quartile, Δ< -22ng/ml), and the stable/persistent group (Δ was within IQR). In the stable/persistent group, urinary NGAL of day 1, day 2, their average, maximum and minimum values were all significantly associated with worsening kidney function (AUC-ROC > .9). On the other hand, only urinary NGAL at day 1, minimum values showed significant associations in the increasing group (AUC-ROC .75). In the decreasing group, urinary NGAL failed to show any significant association with worsening of AKI. However, relative reduction rate was able to predict recovery <strong>from</strong> AKI (AUC-ROC=.72). Conclusion: In the present study, absolute values of urinary NGAL can predict worsening AKI when increased or stable within 24 hr after ICU admission. Relative reduction rate can be used to predict recovery <strong>from</strong> AKI when urinary NGAL decreased after ICU admission. These data indicate serial measurement of urinary NGAL is useful for predicting AKI worsening and recovery 46. Transfusion Related Acute Kidney Injury: Result of a Prospective Cohort Study Ladan Zand, Rodrigo Cartin-Ceba, Kianoush Kashani Mayo Clinic, Rochester, MN Background: Acute kidney injury (AKI) occurs in up to two third of intensive care unit (ICU) patients. It has been shown that blood product transfusion increases risk of acute lung injury (TRALI). Considering strong association between ALI and AKI, we evaluated the association between transfusion and AKI in ICU patients. Methods: We performed a retrospective analysis of a prospectively collected cohort of consecutive adults (>18 years of age) who were admitted to the ICU and received blood product transfusion <strong>from</strong> March 24 to December 25. We excluded those who developed AKI prior to receiving transfusion or who were on chronic hemodialysis at time of admission. Results: A total of 127 patients met the inclusion criteria. The median age was 64 (IQR, 53-77), 65 were male (51%). A total of 49 (38%) patients developed AKI based on the AKIN criteria. In univariate analysis, there was no statistical significant difference in development of AKI based on the type of blood product that the patients received (cryoprecipitate, packed red blood cells, platelets or fresh frozen plasma). After adjustment for age, gender, baseline creatinine and presence of shock upon ICU admission, the transfusion of blood products was not independently associated with development of AKI (Odds ratio 1.6, 95% CI .95-1.18, p=.25). Conclusion: In a cohort of heterogenous group of ICU patient who received blood product transfusion, there was no increased risk of AKI. 158
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CRRT 2012 SEVENTEENTH INTERNATIONAL
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FACULTY DISCLOSURES CRRT 2012 Facul
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CRRT 2012 ORGANIZING COMMITTEE USA
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CRRT 2012 FACULTY Patrick Honoré,
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ACKNOWLEDGEMENTS CRRT 2012 ACKNOWLE
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PLENARY SESSIONS CRRT 2012 PROGRAM/
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WORKSHOPS CRRT 2012 PROGRAM/INDEX T
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WORKSHOPS CRRT 2012 PROGRAM/INDEX W
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POSTER ABSTRACTS C
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POSTER ABSTRACTS C
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NURSING FORUM LUNCHEON Communicatio
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Nutritional Support in ICU Patients
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Educational Objectives: The Endothe
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SPECIAL LECTURE Engineering Critica
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Nishimura R, Ornato JP, Page RL, Ri
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Do Vasoactive Drugs and Fluids Impr
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Blood Transfusions are Important fo
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Thinking Outside of the Box: A Nove
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Nursing Forum 2 Luncheon Benchmarki
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4. Mori K, Lee HT, Rapoport D, Drex
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Differential Diagnosis of AKI: Can
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Myocardial Stunning and Brain Edema
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4. Udy A, Roberts JA, Lipman J. Wha
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CRRT and ECMO: Techniques and Outco
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Management of Severe Heart Failure:
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Avoiding Anticoagulation for CRRT:
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Improving Outcomes from</st
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The Changing Face of AKI: Snapshots
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Alkaline Phosphatase Peter Pickkers
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creatinine (Cr) was measured using
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Surveillance and Early Recognition
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therapy admitted to general intensi
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A01 Assessing the Microcirculation
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A01 Assessing the Microcirculation
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C03 Critical Care Pharmacology: Vas
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D04 Biomarkers 1: Principles and Ap
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6. Ferguson JW, Dover AR, Chia S, C
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G07 Fluids and Solutions in the Cri
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A09 Vascular Access /Membrane and C
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A09 Vascular Access /Membrane and C
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C11 Critical Care Management: Nutri
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D12 Biomarkers 2: Application in AK
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Educational Objectives: E13 Liver a
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G15 Fluids and Solutions in the Cri
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Educational Objectives: 1) Discuss
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B18 Fluid Management Ravindra L. Me
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C19 Acid Base and Electrolyte Probl
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D20 Extracorporeal Techniques for S
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the mediatordelivery hypothesis. In
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F22 Ensuring Patient Safety and Qua
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H24 Patient Centered Care in the IC
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