ABSTRACTS from 16th International COnference on ... - CRRT Online

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<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT, SAN DIEGO, FEB 14-17, 2012 meq/L of K and 12 received 4 meq/L of K. Those with the lower concentration of K required 52 mEq K replacement/day versus 7 mEq K replacement/day with the higher concentration (p
<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT, SAN DIEGO, FEB 14-17, 2012 Median estimated glomerular filtration rate based on serum creatinine (updated Schwartz formula) ranged <strong>from</strong> 19 – 24 ml/min/1.73m2, and median effluent rate ranged <strong>from</strong> 1832 – 2877 ml/min/1.73m2 (Q3 of 2327 – 497 ml/min/1.73m2) between age groups. T > MIC was decreased in younger age groups, but adequate for children above 15 years of age. Q3 effluent rates caused a 6 -14% reduction in T > MIC. (See table). Conclusion: Extracorporeal clearance and high effluent rates may render MP dosing recommendations of 2 mg/kg inadequate for younger age groups receiving CRRT. These in silico PK/PD models will need to be verified prospectively in children receiving MP and CRRT. Age Group < 1 year 1-5 years 5-1 years 1-15 years > 15 years Median Weight (kg) T > MIC (median effluent rate) T > MIC (Q3 effluent rate) 3.6 38% 28% 13.8 58% 52% 24.2 62% 52% 45. 88% 74% 59.9 94% 82% 16. Evaluation of the Potential Adverse Effects Associated with Calcium Carbonate Precipitate During Continuous Veno-Venous Hemofiltration (CVVH) David S Pantaleone, Benjamin Brooks, Justin Daller, Jerome Gass, Jeffrey McKee, Paul Zieske, Paola Mussi, Benoit Moreaux Baxter Healthcare Corporation Purpose: This study evaluated the potential adverse effects associated with exposure to calcium carbonate precipitate in Accusol 35 Solution (Accusol 35) during CVVH. The clinical use of Accusol 35 has been associated with occasional formation of calcium carbonate precipitate in the tubing set during therapy. Methods: 14 dogs were anesthetized, instrumented, and received CVVH with the test (6) or negative control article (8) for 6 hr. The test article was Accusol 35 with induced precipitate formation prior to CVVH, containing visible particles and subvisible particles 36X higher than the maximum concentration specified in European Pharmacopoeia (EP). The negative control article was Accusol 35 conforming to EP specification. Onehalf the dogs in the negative control article group received a central venous injection of Sephadex G-5 beads (1 mg/kg) following CVVH as positive control. Select cardiovascular (CV) parameters (systemic and pulmonary arterial pressures, central venous pressure, heart rate and cardiac output) were monitored continuously, and stroke volume and systemic and pulmonary vascular resistances were calculated at pre-determined times throughout CVVH. Arterial samples were obtained for blood gas analysis. Samples of the test and negative control articles were obtained hourly during CVVH for determination 134
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CRRT 2012 SEVENTEENTH INTERNATIONAL
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FACULTY DISCLOSURES CRRT 2012 Facul
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CRRT 2012 ORGANIZING COMMITTEE USA
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CRRT 2012 FACULTY Patrick Honoré,
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ACKNOWLEDGEMENTS CRRT 2012 ACKNOWLE
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PLENARY SESSIONS CRRT 2012 PROGRAM/
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WORKSHOPS CRRT 2012 PROGRAM/INDEX T
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WORKSHOPS CRRT 2012 PROGRAM/INDEX W
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POSTER ABSTRACTS C
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POSTER ABSTRACTS C
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NURSING FORUM LUNCHEON Communicatio
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Nutritional Support in ICU Patients
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Educational Objectives: The Endothe
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SPECIAL LECTURE Engineering Critica
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Nishimura R, Ornato JP, Page RL, Ri
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Do Vasoactive Drugs and Fluids Impr
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Blood Transfusions are Important fo
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Thinking Outside of the Box: A Nove
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Nursing Forum 2 Luncheon Benchmarki
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4. Mori K, Lee HT, Rapoport D, Drex
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Differential Diagnosis of AKI: Can
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Myocardial Stunning and Brain Edema
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4. Udy A, Roberts JA, Lipman J. Wha
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CRRT and ECMO: Techniques and Outco
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Management of Severe Heart Failure:
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Avoiding Anticoagulation for CRRT:
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Improving Outcomes from</st
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The Changing Face of AKI: Snapshots
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Alkaline Phosphatase Peter Pickkers
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creatinine (Cr) was measured using
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Surveillance and Early Recognition
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therapy admitted to general intensi
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A01 Assessing the Microcirculation
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A01 Assessing the Microcirculation
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C03 Critical Care Pharmacology: Vas
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D04 Biomarkers 1: Principles and Ap
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6. Ferguson JW, Dover AR, Chia S, C
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G07 Fluids and Solutions in the Cri
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A09 Vascular Access /Membrane and C
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Page 86 and 87: C11 Critical Care Management: Nutri
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Page 94 and 95: Educational Objectives: 1) Discuss
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Page 100 and 101: D20 Extracorporeal Techniques for S
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Page 108 and 109: B26 Starting and Stopping RRT for A
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Page 112 and 113: D28 Extracorporeal Techniques for S
Page 114 and 115: E29 Heart Failure and Cardio-Renal
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