ABSTRACTS from 16th International COnference on ... - CRRT Online

<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT,
SAN DIEGO, FEB 14-17, 2012
data of 89 ICU patients with AKI or
acute-on-chronic kidney disease who
received CRRT. We calculated the
SAPS 3 and APACHE II score at the
start of CRRT. Results: The average age
of the 89 patients was 64.4±13.9 years.
Fifty-nine (66.3%) patients were male.
Eighteen (2.2%) patients had chronic
kidney disease and thirty (33.7%)
patients had diabetes. Sixty-two (69.8%)
patients treated with mechanical
ventilation. The average systolic blood
pressure was 85.9±27.4 mmHg, and
sixty-four (71.9%) patients treated with
vasopressor. The overall mortality was
75.3%. The average SAPS 3 was
89.4±14.9 and the average APACHE II
score was 28.4±5.2. The SAPS 3 was
higher in non-survivors than survivors
(p=.38). Sepsis was more common in
non-survivors than survivors (p=.36).
There were no significant differences
between the two groups for other
conditions. The variables influencing
mortality on univariate analysis were
SAPS 3 and presence of sepsis. The area
under the receiver-operating
characteristic curve for SAPS 3 was .69
(95% CI. .54–.83). At a SAPS 3 of 84,
the sensitivity for predicting mortality
was 71.6% and the specificity was
69.2%. Patient survival estimated by
Kaplan-Meier method, patients with low
SAPS3 score (84)
significantly (p=.3). Conclusion: The
SAPS 3 determined before starting
CRRT could be a predictor of hospital
mortality in ICU patients with AKI.
42. Initiation of Acute Renal
Replacement Therapy in ICU
patients based on AKIN criteria in
the absence of conventional
indications fails to improve
survival
Cynthia C LIM, Chieh Suai TAN, Chian
Min LOO, Pang LEE, Han Khim TAN
Department of Renal Medicine,
Singapore General Hospital,
Department of Respiratory and Critical
Care Medicine, Singapore General
Hospital, Surgical Intensive Care Unit,
Singapore General HospitalDepartment
of Respiratory and Critical Care
Medicine, Singapore General Hospital
Introduction: Acute kidney injury
(AKI) in intensive care unit (ICU)
patients is associated with high
mortality. Yet optimal timing of acute
renal replacement therapy (ARRT)
initiation is uncertain. We report
preliminary results of outcomes of
critically ill patients with AKI initiated
on ARRT based on conventional
“absolute” indications (Group 2) versus
modified AKIN criteria (Group 1).
Method: This was a single-center;
prospective, observational study of
patients with AKI <strong>from</strong> Medical (MICU)
and Surgical ICU (SICU) referred
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