ABSTRACTS from 16th International COnference on ... - CRRT Online

<strong>ABSTRACTS</strong> FROM 17 TH INTERNATIONAL CONFERENCE ON CRRT,
SAN DIEGO, FEB 14-17, 2012
This study aimed to investigate the
clinical efficacy of PMMA-CHDF in the
treatment of a patients with sepsis and
ARDS. Methods: Thirty- five patients
diagnosed with sepsis (ARDS[n=1],
Pyelonephritis [n=5], Cholangitis [n=5],
Tsutugamusi in Scrub typhus
disease[n=1],Snake Mamushi
bitten[n=1], haemophagocytic
syndrome[n=1],anti neutrophil
cytoplasmic antibody(ANCA )lung
disiese[n=1],beriberi heart disease[n=1]
and unknown causes[n=8] )were
enrolled in this study between August 21
and November211.The common cause
for ARDS in elderly patients aspiration
pneumonia in elderly patients. Our study
group composed 15men and 2women,
aged 35 -85 years (median age 68years).
Results: Before initiating treatment with
the PMMA-CHDF,the average
APACHEⅡscore of these patients was
17.5+/-3.6 ,whereas the average SOFA
score was 6.5+/-1.3. The duration of
PMMA-CHDF treatment was5.2+/-
2.3days. Following initiation of PMMA-
CHDF teatment, early improvement of
haemodynamics was observed,along
with an increase in the urine output. The
average survival rates of patients
were75.6%. The low survival rate
among diseases 35% belonged to the
Unknown group. The highest survival
rate for patients with ARDS was
95%.Moreover,the urine output
significantly increased in survival group.
Conclusion:The present study suggests
that cytokine-oriented critical care using
PMMA-CHDF might be effective the
treatment of sepsis and ARDS,
particularly,in the treatment of ARDS
associated with aspiration pneumonia in
elderly patients.
20. Prophylactic Peritoneal Dialysis
Improves Clinical Outcomes in
Children Following Open-Heart
Surgery with Cardiopulmonary
Bypass
William C Sasser III, David J Askenazi,
Ashley Moellinger, Santiago Borasino,
Kristal Hock, Robert J Dabal, James K
Kirklin, Jeffrey A Alten
University of Alabama at Birmingham,
Birmingham, AL, USA
Purpose: To investigate the impact of
prophylactic peritoneal dialysis (PD) on
clinical outcomes after open-heart
surgery in children with complex
congenital heart disease. We hypothesize
that compared to passive peritoneal
drainage and diuretic therapy,
prophylactic PD will lead to improved
clinical outcomes including shorter
duration of mechanical ventilation
(primary endpoint). Methods: We
performed a prospective before-and-after
cohort study of 52 consecutive children
at high risk for post-cardiopulmonary
bypass (CPB) fluid overload. 27 patients
that received diuretic therapy and
passive peritoneal drainage (-PD)
(before Jan 211) were compared to 25
patients that did not receive diuretics and
were initiated on prophylactic PD (+PD)
within the first 6hrs of admission (per
new CICU protocol starting Jan 211).
Results: There was no difference in
demographics, CPB time, surgical
diagnoses, lactate or hemodynamic
variables between groups. +PD
demonstrated significantly less positive
fluid balance after CICU admission at
both 24hrs [+PD -24.3mL/kg (IQR -
6.2,3) vs. -PD 17.5mL/kg (IQR -
24.8,61.7), p=.3] and 48hrs [+PD -
88mL/kg (IQR-132.1,-54.2 vs. -PD -
45.8mL/kg (IQR -82.3,-12.4), p=.4].
24hr urine output was similar between
groups but higher in -PD at 48hrs [+PD
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